{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:41:03Z","timestamp":1777513263260,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T00:00:00Z","timestamp":1157068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2006,9]]},"abstract":"\n Background:<\/jats:title>\n Current therapeutic options for the treatment of pemphigus vulgaris (PV) are prednisone and immunosuppressants. Patients unresponsive to high-dose systemic corticosteroids and conventional immunosuppressants may respond to intravenous immunoglobulin (IVIG).<\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n The primary outcome was the change in prednisone dose at 6 months and 1 year post-IVIG administration.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A retrospective chart review of PV patients treated at Sunnybrook and Women's College Health Sciences Centre between January 1999 and October 2004 was conducted. Demographic information, corticosteroid and IVIG use, dosage, and the timing of administration for all patients were obtained.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Eight PV patients, mean age of 50 years (\u00b1 14.7 years), were reviewed. There was a significant decrease in mean prednisone dose at 6 months (45%) and 12 months (71%) compared with the mean dose at the start of treatment ( p < .05).<\/jats:p>\n <\/jats:sec>\n \n Limitations:<\/jats:title>\n Concomitant medication use may influence results.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n This study demonstrates that IVIG can lower prednisone doses in PV patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.2310\/7750.2006.00053","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"222-227","source":"Crossref","is-referenced-by-count":8,"title":["Effect of Intravenous Immunoglobulin on Prednisone Dose in Patients with Pemphigus Vulgaris"],"prefix":"10.1177","volume":"10","author":[{"given":"Nicole","family":"Mittmann","sequence":"first","affiliation":[{"name":"From the Division of Clinical Pharmacology, Department of Medicine, Sunnybrook Health Sciences Centre; Department of Pharmacology, University of Toronto; Health Outcomes and Pharmacoeconomics Research Centre, Toronto, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Chan","sequence":"additional","affiliation":[{"name":"From the Division of Clinical Pharmacology, Department of Medicine, Sunnybrook Health Sciences Centre; Department of Pharmacology, University of Toronto; Health Outcomes and Pharmacoeconomics Research Centre, Toronto, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Knowles","sequence":"additional","affiliation":[{"name":"From the Division of Clinical Pharmacology, Department of Medicine, Sunnybrook Health Sciences Centre; Department of Pharmacology, University of Toronto; Health Outcomes and Pharmacoeconomics Research Centre, Toronto, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. R\u00e9gine","family":"Mydlarski","sequence":"additional","affiliation":[{"name":"From the Division of Clinical Pharmacology, Department of Medicine, Sunnybrook Health Sciences Centre; Department of Pharmacology, University of Toronto; Health Outcomes and Pharmacoeconomics Research Centre, Toronto, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"Cosentino","sequence":"additional","affiliation":[{"name":"From the Division of Clinical Pharmacology, Department of Medicine, Sunnybrook Health Sciences Centre; Department of Pharmacology, University of Toronto; Health Outcomes and Pharmacoeconomics Research Centre, Toronto, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Shear","sequence":"additional","affiliation":[{"name":"From the Division of Clinical Pharmacology, Department of Medicine, Sunnybrook Health Sciences Centre; Department of Pharmacology, University of Toronto; Health Outcomes and Pharmacoeconomics Research Centre, Toronto, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,9,1]]},"reference":[{"key":"bibr1-7750.2006.00053","first-page":"654","volume-title":"Fitzpatrick's dermatology in general medicine","author":"Stanley JR","year":"1999","edition":"5"},{"key":"bibr2-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(74)90365-X"},{"key":"bibr3-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.2340\/0001555562491496"},{"key":"bibr4-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1980.01640330073017"},{"key":"bibr5-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2003.05665.x"},{"key":"bibr6-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1984.01650370050009"},{"key":"bibr7-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1990.tb04765.x"},{"key":"bibr8-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(08)81506-X"},{"key":"bibr9-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1984.01650430127024"},{"key":"bibr10-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.7.868"},{"key":"bibr11-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90213-5"},{"key":"bibr12-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.8.1051"},{"key":"bibr13-7750.2006.00053","volume-title":"Principles of corticosteroid therapy","author":"Lin AN","year":"2002","edition":"1"},{"key":"bibr14-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.116339"},{"key":"bibr15-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.138.9.1158"},{"key":"bibr16-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2005.02834.x"},{"key":"bibr17-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2005.02947.x"},{"key":"bibr18-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.139.8.1051"},{"key":"bibr19-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.108366"},{"key":"bibr20-7750.2006.00053","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01540.x"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2006.00053","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2006.00053","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2006.00053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:47:51Z","timestamp":1777391271000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2006.00053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["10.2310\/7750.2006.00053"],"URL":"https:\/\/doi.org\/10.2310\/7750.2006.00053","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9]]}}}