{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:30:45Z","timestamp":1791912645292,"version":"4.3.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2007,11]]},"abstract":"\n Background:<\/jats:title>\n Although more than 25 acne grading systems exist, only 2 are inclusive of truncal acne. There is neither a gold standard nor a consistently used standardized system.<\/jats:p>\n <\/jats:sec>\n \n Purpose:<\/jats:title>\n Our purpose was to develop and validate an acne grading system incorporating severity at the face, chest, and back.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n We developed a comprehensive acne severity scale (CASS) by modifying a preexisting facial acne scale, the Investigator Global Assessment, to include truncal acne. The validity and responsiveness of CASS grades were correlated with Leeds scores at baseline and after 6 months of standard acne treatment.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Spearman correlations were significant between Leeds and CASS grades for the face (0.823), chest (0.854), and back (0.872), respectively ( p < .001). After 6 months of therapy, changes in these scores were also significantly correlated ( p < .001) at all three sites.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Concurrent validity of CASS is demonstrated by a very strong correlation with Leeds grading. CASS is simpler to use than the Leeds system and more appropriate for translation of research trial results to clinical practice.<\/jats:p>\n <\/jats:sec>","DOI":"10.2310\/7750.2007.00037","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"211-216","source":"Crossref","is-referenced-by-count":125,"title":["Development and Validation of a Comprehensive Acne Severity Scale"],"prefix":"10.1177","volume":"11","author":[{"given":"Jerry K.L.","family":"Tan","sequence":"first","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Tang","sequence":"additional","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Fung","sequence":"additional","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya K.","family":"Gupta","sequence":"additional","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Richard","family":"Thomas","sequence":"additional","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheetal","family":"Sapra","sequence":"additional","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Lynde","sequence":"additional","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Poulin","sequence":"additional","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Gulliver","sequence":"additional","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf J.","family":"Sebaldt","sequence":"additional","affiliation":[{"name":"From the University of Western Ontario, London, ON, Windsor Clinical Research Inc., Windsor, ON; Department of Mathematics and Statistics, University of Windsor, Windsor, ON; Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, ON, and Mediprobe Research Inc., London, ON; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Institute of Cosmetic and Laser Suregery, Oakville, ON; University of..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2007,11,1]]},"reference":[{"key":"bibr1-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.120912"},{"key":"bibr2-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.1997.tb01126.x"},{"key":"bibr3-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.3109\/09546639809160698"},{"key":"bibr4-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1997.00099.x"},{"key":"bibr5-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1982.01650130027012"},{"key":"bibr6-7750.2007.00037","unstructured":"US Department of Health and Human Services, Food and Drug Administration (November 2002). Dermatologic and Ophthalmic Drugs Advisory Committee Briefing. Available at: http:\/\/www.fda.gov\/ohrms\/dockets\/ac\/02\/briefing\/3904B1_02_Executive%20Summary.htm (accessed July 1, 2004)."},{"key":"bibr7-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2004.03.008"},{"key":"bibr8-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(08)80076-X"},{"key":"bibr9-7750.2007.00037","unstructured":"US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). Guidance for industry; acne vulgaris: developing drugs for treatment; September 2005; 1\u201314. Available at: http:\/\/www.fda.gov\/Cder\/guidance\/6499dft.htm (accessed February 12, 2005)."},{"key":"bibr10-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90680-5"},{"key":"bibr11-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2006.00044"},{"key":"bibr12-7750.2007.00037","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-006-0063-3"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2007.00037","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2007.00037","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2007.00037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:48:03Z","timestamp":1777391283000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2007.00037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["10.2310\/7750.2007.00037"],"URL":"https:\/\/doi.org\/10.2310\/7750.2007.00037","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}