{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:43:02Z","timestamp":1777513382319,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2009,1]]},"abstract":"\n Background:<\/jats:title>\n Alopecia areata is a nonscarring hair loss characterized by well-circumscribed patchy areas, most often on the scalp. The inflammatory cytokine tumor necrosis factor alpha (TNF-\u03b1), has been connected with the development of alopecia areata in vivo; thus, the TNF-\u03b1 inhibitors have been cited as possible treatments for this autoimmune condition.<\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n We report a case of alopecia areata that developed in a 52-year-old woman who was recently started on adalimumab for treatment of her psoriatic arthritis.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n We discuss the previously published cases in the literature linking alopecia areata to TNF-\u03b1 inhibitor administration. Our case is the first report of a new-onset alopecia areata following adalimumab.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Even though TNF-\u03b1 is implicated in causing alopecia areata, TNF-\u03b1 inhibitors have paradoxically been associated with new cases of alopecia areata. It is possible that TNF-\u03b1 may not be involved in the pathogenesis of alopecia areata, as in vitro studies have suggested.<\/jats:p>\n <\/jats:sec>","DOI":"10.2310\/7750.2008.07095","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"48-50","source":"Crossref","is-referenced-by-count":35,"title":["Alopecia Areata following Adalimumab"],"prefix":"10.1177","volume":"13","author":[{"given":"Carly","family":"Kirshen","sequence":"first","affiliation":[{"name":"From the Department of Dermatology, University of Ottawa, Ottawa, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nordau","family":"Kanigsberg","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, University of Ottawa, Ottawa, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,1,1]]},"reference":[{"key":"bibr1-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2007.03193.x"},{"key":"bibr2-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12471877"},{"key":"bibr3-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)06943-4"},{"key":"bibr4-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jidsp.5640212"},{"key":"bibr5-7750.2008.07095","first-page":"1806","volume":"29","author":"Gottenberg JE","year":"2002","journal-title":"J Rheumatol"},{"key":"bibr6-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1017\/S146239940601101X"},{"key":"bibr7-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1996.d01-1099.x"},{"key":"bibr8-7750.2008.07095","first-page":"218","volume":"140","author":"Kreuger G","year":"2004","journal-title":"Arch Dermatol"},{"key":"bibr9-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.6.759"},{"key":"bibr10-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07682.x"},{"key":"bibr11-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1159\/000069965"},{"key":"bibr12-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.8.1012-a"},{"key":"bibr13-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.142.12.1653"},{"key":"bibr14-7750.2008.07095","first-page":"1654","volume":"142","author":"Bartels NG","year":"2006","journal-title":"Arch Dermatol"},{"key":"bibr15-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.03.039"},{"key":"bibr16-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-9740.2006.05443.x"},{"key":"bibr17-7750.2008.07095","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12395722"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2008.07095","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2008.07095","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2008.07095","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:48:16Z","timestamp":1777391296000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2008.07095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["10.2310\/7750.2008.07095"],"URL":"https:\/\/doi.org\/10.2310\/7750.2008.07095","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}