{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:43:43Z","timestamp":1777513423743,"version":"3.51.4"},"reference-count":5,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>With increasing use of immunosuppressive therapy, including tumor necrosis factor a inhibitors, there is concern about infectious complications, including reactivation of latent Mycobacterium tuberculosis infection. Routine testing prior to administration of systemic immunosuppression includes the tuberculin skin test, which lacks sensitivity and specificity and may be difficult to interpret in the presence of extensive cutaneous disease. Treatment of individuals with latent tuberculosis infection is recommended when immunosuppressive medications are to be employed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Observations:<\/jats:title>\n                    <jats:p>We report a case in which a diagnosis of latent tuberculosis infection in a patient with extensive bullous pemphigoid was clarified by the use of an interferon-\u03b3 release assay after equivocal tuberculin skin test results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Interferon-\u03b3 release assays are useful adjuncts to the tuberculin skin test in the diagnosis of latent tuberculosis infection in the setting of extensive cutaneous disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2310\/7750.2009.08062","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"280-282","source":"Crossref","is-referenced-by-count":1,"title":["Utility of an Interferon-\u03b3 Release Assay for Latent Tuberculosis Diagnosis in a Case of Bullous Pemphigoid"],"prefix":"10.1177","volume":"13","author":[{"given":"Alfred","family":"Goodfellow","sequence":"first","affiliation":[{"name":"From the Department of Dermatology; Department of Infectious Disease, Saint John Regional Hospital, Saint John, NB"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas N.","family":"Keeling","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology; Department of Infectious Disease, Saint John Regional Hospital, Saint John, NB"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Hayes","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology; Department of Infectious Disease, Saint John Regional Hospital, Saint John, NB"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duncan","family":"Webster","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology; Department of Infectious Disease, Saint John Regional Hospital, Saint John, NB"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,9,1]]},"reference":[{"key":"bibr1-7750.2009.08062","volume":"3","author":"Khamalo N","year":"2005","journal-title":"Cochrane Database of Syst Rev"},{"key":"bibr2-7750.2009.08062","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-146-5-200703060-00006"},{"key":"bibr3-7750.2009.08062","first-page":"1","volume":"33","author":"Gardam M","year":"2007","journal-title":"Can Commun Dis Rep"},{"key":"bibr4-7750.2009.08062","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02742-2"},{"key":"bibr5-7750.2009.08062","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011592"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2009.08062","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2009.08062","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2009.08062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:48:26Z","timestamp":1777391306000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2009.08062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":5,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["10.2310\/7750.2009.08062"],"URL":"https:\/\/doi.org\/10.2310\/7750.2009.08062","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9]]}}}