{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T18:56:57Z","timestamp":1791053817704,"version":"4.1.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background\/Objectives:<\/jats:title>\n                    <jats:p>There are limited data on the clinical presentation and progression of pediatric cutaneous lymphoma. This study focuses on the clinical characteristics of pediatric patients with mycosis fungoides (MF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This descriptive study presents clinical characteristics of 22 pediatric patients with MF, enrolled in the international Childhood Registry for Cutaneous Lymphomas (CRCL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean ages at onset and at diagnosis were 7.5 (SD 3.8 years) years and 9.9 (SD 3.4) years, respectively. The most common MF presentation was patch stage (68%), followed by hypopigmentation (59%) and plaque stage disease (50%). Epidermotropism and lymphocytic atypia were the most common pathologic features, found in 89% and 85%, respectively. Cerebriform nuclei were noted in 42%, and Pautrier microabscesses were seen in 16% of cases. A cytotoxic pattern was more commonly seen (67% vs 33%), and clonality was detected in 21% (3 of 14) of patients. All patients presented with early-stage disease and received skin-directed therapy (topical steroids, 73%; light therapy, 54%; or combination therapy, 35%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Pediatric patients with MF present in the first decade of life, with early-stage disease and unusual forms such as hypopigmented variant. Further patient enrolment will provide information regarding natural history, treatment response, and overall prognosis of pediatric cutaneous T-cell lymphoma (CTCL).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2310\/7750.2009.08091","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"1-6","source":"Crossref","is-referenced-by-count":85,"title":["Mycosis Fungoides in the Pediatric Population: Report from an International Childhood Registry of Cutaneous Lymphoma"],"prefix":"10.1177","volume":"14","author":[{"given":"Elena","family":"Pope","sequence":"first","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Weitzman","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Ngan","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Walsh","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Morel","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Williams","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Stein","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Garzon","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Knobler","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colette","family":"Lieber","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Turchan","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orli","family":"Wargon","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arline","family":"Tsuchiya","sequence":"additional","affiliation":[{"name":"From the Section of Dermatology, Division of Hematology\/Oncology, and Department of Laboratory Medicine, The Hospital for Sick Children, Toronto, ON; Columbia University\/Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY; Eastern Virginia Medical School, Norfolk, VA; Section of Dermatology, University of Chicago, Chicago, IL; Columbia University, New York, NY; Private Practice, Englewood, NJ; Community Hospital North Professionals, Indianapolis, IN; School of Women's and Children's..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,1,1]]},"reference":[{"key":"bibr1-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03410010050033"},{"key":"bibr2-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.7.854"},{"key":"bibr3-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.89.8.1240"},{"key":"bibr4-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2006.00494.x"},{"key":"bibr5-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06905.x"},{"key":"bibr6-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"bibr7-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1159\/000063906"},{"key":"bibr8-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1990.01670350063008"},{"key":"bibr9-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.03232.x"},{"key":"bibr10-7750.2009.08091","first-page":"725","volume":"63","author":"Bunn PA","year":"1979","journal-title":"Cancer Treat Rep"},{"key":"bibr11-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.08.057"},{"key":"bibr12-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1111\/j.0736-8046.2004.21500.x"},{"key":"bibr13-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)70243-3"},{"key":"bibr14-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11780"},{"key":"bibr15-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1080\/00015550310020530"},{"key":"bibr16-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1097\/01.dad.0000144161.49294.5a"},{"key":"bibr17-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2007.00858.x"},{"key":"bibr18-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06760.x"},{"key":"bibr19-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.12.1483"},{"key":"bibr20-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1053\/hupa.2002.125381"},{"key":"bibr21-7750.2009.08091","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08761.x"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2009.08091","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2009.08091","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2009.08091","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:48:35Z","timestamp":1777391315000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2009.08091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["10.2310\/7750.2009.08091"],"URL":"https:\/\/doi.org\/10.2310\/7750.2009.08091","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1]]}}}