{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:44:27Z","timestamp":1777513467307,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Erythema nodosum leprosum (ENL) is a disease rarely encountered in Canada. It is characterized by multiple remissions and recurrences, often requires long-term treatment, and can result in debilitating sequelae.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To promote rapid recognition and adequate therapy for ENL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Case report of a 39-year-old man diagnosed with an ENL. The clinical and histopathologic features, treatment provided, and response to treatment are detailed in this article.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>ENL presented itself as painful cutaneous lesions on the face and limbs, bilateral paresthesia of the fourth and fifth fingers, and systemic symptoms. Prednisone 40 mg daily for a week and then 60 mg daily for another week reduced the lesions by 80% and the pain by 50%. Although prednisone 60 mg daily was continued for one more week and then stopped, thalidomide was started at a dose of 300 mg daily for 4 weeks and then reduced gradually, which led to complete resolution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>At the 7\u00bd-month follow-up, the patient remained completely asymptomatic.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2310\/7750.2009.08094","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"95-99","source":"Crossref","is-referenced-by-count":4,"title":["Canadian Case Report of Erythema Nodosum Leprosum Successfully Treated with Prednisone and Thalidomide"],"prefix":"10.1177","volume":"14","author":[{"given":"M\u00e9lissa","family":"Saber","sequence":"first","affiliation":[{"name":"From the Departments of Dermatology and Pathology, CHUM, University of Montreal, Montreal, QC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Bourassa-Fulop","sequence":"additional","affiliation":[{"name":"From the Departments of Dermatology and Pathology, CHUM, University of Montreal, Montreal, QC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Bouffard","sequence":"additional","affiliation":[{"name":"From the Departments of Dermatology and Pathology, CHUM, University of Montreal, Montreal, QC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Provost","sequence":"additional","affiliation":[{"name":"From the Departments of Dermatology and Pathology, CHUM, University of Montreal, Montreal, QC"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,3,1]]},"reference":[{"key":"bibr1-7750.2009.08094","first-page":"71","volume":"170","author":"Boggild AK","year":"2004","journal-title":"CMAJ"},{"key":"bibr2-7750.2009.08094","first-page":"55","volume":"170","author":"Boggild AK","year":"2004","journal-title":"CMAJ"},{"key":"bibr3-7750.2009.08094","doi-asserted-by":"publisher","DOI":"10.1016\/S1286-4579(02)01645-3"},{"key":"bibr4-7750.2009.08094","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2006.05.012"},{"key":"bibr5-7750.2009.08094","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15952-7"},{"key":"bibr6-7750.2009.08094","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2006.74.868"},{"key":"bibr7-7750.2009.08094","doi-asserted-by":"publisher","DOI":"10.1086\/498216"},{"key":"bibr8-7750.2009.08094","first-page":"49","volume":"79","author":"Girdhar BK","year":"2007","journal-title":"Indian J Lepr"},{"key":"bibr9-7750.2009.08094","first-page":"199","volume":"46","author":"Pearson JMH","year":"1975","journal-title":"Lepr Rev"},{"key":"bibr10-7750.2009.08094","doi-asserted-by":"publisher","DOI":"10.47276\/lr.78.3.197"},{"key":"bibr11-7750.2009.08094","unstructured":"ILEP. The management of erythema nodosum leprosum. Technical bulletin 9. Available at: http:\/\/www.ilep.org.uk\/technical-advice\/guidelines-practice\/technical-bulletin-9\/ (accessed October 2008)."},{"key":"bibr12-7750.2009.08094","first-page":"2886","volume-title":"Principles and practice of infectious diseases","author":"Levis WR","year":"2005","edition":"6"},{"key":"bibr13-7750.2009.08094","doi-asserted-by":"publisher","DOI":"10.47276\/lr.75.1.86"},{"key":"bibr14-7750.2009.08094","unstructured":"World Health Organization. Leprosy: the treatment. Available at: http:\/\/www.searo.who.int\/EN\/Section10\/Section20\/Section57_9882.htm (accessed September 2008)."},{"key":"bibr15-7750.2009.08094","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2007.02.010"},{"key":"bibr16-7750.2009.08094","first-page":"287","volume-title":"Textbook of dermatopathology","author":"Barnhill RL","year":"2003","edition":"2"},{"key":"bibr17-7750.2009.08094","doi-asserted-by":"crossref","first-page":"1","DOI":"10.47102\/annals-acadmedsg.V37N1p1","volume":"37","author":"Scollard DM","year":"2008","journal-title":"Ann Acad Med Singapore"},{"key":"bibr18-7750.2009.08094","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2005.72.518"},{"key":"bibr19-7750.2009.08094","first-page":"290","volume":"74","author":"Lockwood DN","year":"2003","journal-title":"Lepr Rev"},{"key":"bibr20-7750.2009.08094","unstructured":"World Health Organization. WHO guidelines for the management of severe erythema nodosum leprosum (ENL) reactions. Available at: http:\/\/www.who.int\/lep\/research\/WHOenlguide.pdf (accessed October 2008)."}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2009.08094","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2009.08094","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2009.08094","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:48:36Z","timestamp":1777391316000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2009.08094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["10.2310\/7750.2009.08094"],"URL":"https:\/\/doi.org\/10.2310\/7750.2009.08094","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3]]}}}