{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:48:57Z","timestamp":1777513737196,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Pityriasis rubra pilaris (PRP) is a rare dermatosis of unknown etiology. Most cases of PRP are sporadic; however, rare cases of familial PRP have been reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To present a case of PRP inherited in an autosomal dominant (AD) fashion and to evaluate the current literature on familial PRP and formulate a comprehensive, up-to-date summary of this rare condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>PubMed was used to conduct a search for articles pertaining to familial PRP published through May 2011.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The first documented case was published in 1910, and 36 subsequent familial cases of PRP have been reported. Familial PRP typically presents very early in childhood, has a gradual onset, and persists throughout life. Given the rarity of this subtype, determining the best therapy has been a challenge. In the pediatric population, a conservative treatment approach, including topical therapy, is frequently used, whereas systemic treatments are reserved for patients with a severe disease that is refractory to therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Rare cases of PRP inherited in an AD fashion have been described and tend to have a chronic clinical course and are treatment refractory. Therefore, the awareness of familial PRP is important for early and accurate diagnosis and administration of appropriate therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2310\/7750.2012.12018","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"226-232","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Familial Pityriasis Rubra Pilaris: Case Report and Review"],"prefix":"10.1177","volume":"17","author":[{"given":"Joshua M.","family":"Mercer","sequence":"first","affiliation":[{"name":"From the Discipline of Medicine, Faculty of Medicine, Memorial University of Newfoundland, and Nexus Clinical Research, St. John's, NL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chitra","family":"Pushpanthan","sequence":"additional","affiliation":[{"name":"From the Discipline of Medicine, Faculty of Medicine, Memorial University of Newfoundland, and Nexus Clinical Research, St. John's, NL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Canagasundrum","family":"Anandakrishnan","sequence":"additional","affiliation":[{"name":"From the Discipline of Medicine, Faculty of Medicine, Memorial University of Newfoundland, and Nexus Clinical Research, St. John's, NL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian D.R.","family":"Landells","sequence":"additional","affiliation":[{"name":"From the Discipline of Medicine, Faculty of Medicine, Memorial University of Newfoundland, and Nexus Clinical Research, St. John's, NL"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,7,1]]},"reference":[{"key":"bibr1-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.2165\/11530070-000000000-00000"},{"key":"bibr2-7750.2012.12018","first-page":"448","volume":"17","author":"Pincus DJ","year":"2005","journal-title":"Dermatol Nurs"},{"key":"bibr3-7750.2012.12018","first-page":"844","volume":"9","author":"Vasher M","year":"2010","journal-title":"J Drugs Dermatol"},{"key":"bibr4-7750.2012.12018","first-page":"58","volume":"61","author":"Griffiths WA","year":"1975","journal-title":"Trans St Johns Hosp Dermatol Soc"},{"key":"bibr5-7750.2012.12018","first-page":"371","volume":"28","author":"Kint A","year":"1972","journal-title":"Arch Belg Dermatol Syphiligr"},{"key":"bibr6-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1958.tb13788.x"},{"key":"bibr7-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-9740.2002.01663.x"},{"key":"bibr8-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07938.x"},{"key":"bibr9-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1995.01690160076012"},{"key":"bibr10-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1923.02360080054004"},{"key":"bibr11-7750.2012.12018","first-page":"609","volume":"1","author":"De Beurmann","year":"1910","journal-title":"Ann Derm Syph"},{"key":"bibr12-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1976.tb01397.x"},{"key":"bibr13-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.02666.x"},{"key":"bibr14-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1980.tb01676.x"},{"key":"bibr15-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.124619"},{"key":"bibr16-7750.2012.12018","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198608000-00001"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2012.12018","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2012.12018","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2012.12018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:49:43Z","timestamp":1777391383000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2012.12018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.2310\/7750.2012.12018"],"URL":"https:\/\/doi.org\/10.2310\/7750.2012.12018","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}