{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T01:55:12Z","timestamp":1791078912034,"version":"4.1.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Cutaneous xanthomas develop as a result of intracellular and dermal deposition of lipids in either hyper- or normolipidemic patients. Plane xanthomas may signal the presence of an underlying monoclonal gammopathy, chronic myelomonocytic leukemia, or cutaneous T-cell lymphoma. Investigators have suggested that xanthomatized T cells may result in induction of plane xanthomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We report the case of a patient with mycosis fungoides (MF) and plane xanthomas who was treated with bexarotene for his MF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Significant improvement in the clinical signs of MF was observed within 3 months. We also observed a substantial regression of the xanthomas after 5 months of treatment. Complete clinical remission of both the MF and xanthomas was obtained after 6 months. The patient was still free of xanthomas after 3 years of follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Bexarotene led to the clearing of the cutaneous lesions of cutaneous T-cell lymphoma and plane xanthomas. This may be due to an effect of bexarotene on the aberrant T cells that may cause xanthomatization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2310\/7750.2012.12022","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"52-54","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Treatment of Mycosis Fungoides with Bexarotene Results in Remission of Diffuse Plane Xanthomas"],"prefix":"10.1177","volume":"17","author":[{"given":"Stamatis","family":"Gregoriou","sequence":"first","affiliation":[{"name":"From the University of Athens Medical School, Department of Dermatology, Attikon Hospital, and the 2nd Department of Dermatology, Andreas Sygros Hospital, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitris","family":"Rigopoulos","sequence":"additional","affiliation":[{"name":"From the University of Athens Medical School, Department of Dermatology, Attikon Hospital, and the 2nd Department of Dermatology, Andreas Sygros Hospital, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Stamou","sequence":"additional","affiliation":[{"name":"From the University of Athens Medical School, Department of Dermatology, Attikon Hospital, and the 2nd Department of Dermatology, Andreas Sygros Hospital, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliki","family":"Nikolaou","sequence":"additional","affiliation":[{"name":"From the University of Athens Medical School, Department of Dermatology, Attikon Hospital, and the 2nd Department of Dermatology, Andreas Sygros Hospital, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Kontochristopoulos","sequence":"additional","affiliation":[{"name":"From the University of Athens Medical School, Department of Dermatology, Attikon Hospital, and the 2nd Department of Dermatology, Andreas Sygros Hospital, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,1,1]]},"reference":[{"key":"bibr1-7750.2012.12022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2003.01829.x"},{"key":"bibr2-7750.2012.12022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07975.x"},{"key":"bibr3-7750.2012.12022","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2006.00051"},{"key":"bibr4-7750.2012.12022","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03557.x"},{"key":"bibr5-7750.2012.12022","first-page":"758","volume":"77","author":"Degos R","year":"1970","journal-title":"Bull Soc Fr Dermatol Syphiligr"},{"key":"bibr6-7750.2012.12022","first-page":"345","volume":"24","author":"Uno A","year":"1982","journal-title":"Rinsho Derma"},{"key":"bibr7-7750.2012.12022","first-page":"627","volume":"108","author":"Nishitani T","year":"1998","journal-title":"Jpm J Dermatol"},{"key":"bibr8-7750.2012.12022","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1992.01680210077011"},{"key":"bibr9-7750.2012.12022","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-7310(05)75060-2"},{"key":"bibr10-7750.2012.12022","first-page":"764","volume":"9","author":"Pothiawala SZ","year":"2010","journal-title":"J Drugs Dermatol"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2012.12022","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2012.12022","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2012.12022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:49:36Z","timestamp":1777391376000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2012.12022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.2310\/7750.2012.12022"],"URL":"https:\/\/doi.org\/10.2310\/7750.2012.12022","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}