{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:50:31Z","timestamp":1777513831195,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Interferon alfa-2b is a treatment option for select patients with stage 3 melanoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To highlight the potential complication of acute rhabdomyolysis from interferon alfa-2b in this patient population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We present a case of a 63-year-old female with stage IIIc melanoma who developed acute rhabdomyolysis after completing 2 of 4 weeks of induction with high-dose interferon alfa-2b. She recovered after hydration with intravenous fluids and discontinuation of interferon alfa-2b.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Review of the literature revealed eight cases of reported rhabdomyolysis triggered by interferon use, including four cases of melanoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In patients treated with interferon, especially at high doses, screening for creatine kinase and myoglobinuria should be performed if the patient develops symptoms suggestive of acute rhabdomyolysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2310\/7750.2013.13115","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"277-279","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Acute Rhabdomyolysis as a Complication of Interferon Treatment for Stage IIIc Melanoma"],"prefix":"10.1177","volume":"18","author":[{"given":"Genevi\u00e8ve","family":"Gavigan","sequence":"first","affiliation":[{"name":"From the Ottawa Hospital Research Institute and Departments of Dermatology and Medical Oncology, University of Ottawa, Ottawa, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alana","family":"McEvoy","sequence":"additional","affiliation":[{"name":"From the Ottawa Hospital Research Institute and Departments of Dermatology and Medical Oncology, University of Ottawa, Ottawa, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vince","family":"Young","sequence":"additional","affiliation":[{"name":"From the Ottawa Hospital Research Institute and Departments of Dermatology and Medical Oncology, University of Ottawa, Ottawa, ON"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,7,1]]},"reference":[{"key":"bibr1-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.09.041"},{"key":"bibr2-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2011.12.002"},{"key":"bibr3-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V1181553"},{"key":"bibr4-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.309.6953.512a"},{"key":"bibr5-7750.2013.13115","first-page":"940","volume":"98","author":"Gabrielli M","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"bibr6-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)80091-8"},{"key":"bibr7-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.03995.x"},{"key":"bibr8-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1080\/09546630152607916"},{"key":"bibr9-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.72.2.274"},{"key":"bibr10-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19950815)76:4<678::AID-CNCR2820760422>3.0.CO;2-Q"},{"key":"bibr11-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.17.3794"},{"key":"bibr12-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp090299"},{"key":"bibr13-7750.2013.13115","doi-asserted-by":"publisher","DOI":"10.4103\/0971-4065.111853"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2013.13115","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2013.13115","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2013.13115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:50:08Z","timestamp":1777391408000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2013.13115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.2310\/7750.2013.13115"],"URL":"https:\/\/doi.org\/10.2310\/7750.2013.13115","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}