{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:07:26Z","timestamp":1792166846054,"version":"4.4.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We report two cases of mosaic generalized neurofibromatosis 1 (NF1) and review the history of the classification of segmental neurofibromatosis (SNF; Ricardi type NF-V). Somatic mutations giving rise to limited disease, such as segmental neurofibromatosis are manifestations of mosaicism. If the mutation occurs before tissue differentiation, the clinical phenotype will be generalized disease. Mutations that occur later in development give rise to disease that is confined to a single region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Segmental neurofibromatosis is caused by a somatic mutation of neurofibromatosis type 1, and should not be regarded as a distinct entity from neurofibromatosis 1. Cases previously referred to as unilateral or bilateral segmental neurofibromatosis are now best referred to as mosaic generalized or mosaic localized neurofibromatosis 1.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2310\/7750.2013.13116","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"271-274","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Mosaic Generalized Neurofibromatosis 1: Report of Two Cases"],"prefix":"10.1177","volume":"18","author":[{"given":"Jori","family":"Hardin","sequence":"first","affiliation":[{"name":"From the Division of Dermatology, University of Calgary, Calgary, AB"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Behm","sequence":"additional","affiliation":[{"name":"From the Division of Dermatology, University of Calgary, Calgary, AB"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard M.","family":"Haber","sequence":"additional","affiliation":[{"name":"From the Division of Dermatology, University of Calgary, Calgary, AB"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,7]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.11.1433"},{"key":"e_1_3_2_3_2","first-page":"712","article-title":"Localized neurofibromatosis","volume":"24","author":"Gammel J","year":"1931","unstructured":"Gammel J. Localized neurofibromatosis. Arch Dermatol Syphilol 1931;24:712, doi:10.1001\/archderm.1931.01450010722022.","journal-title":"Arch Dermatol Syphilol"},{"key":"e_1_3_2_4_2","first-page":"1","volume-title":"A clinical, pathological, and genetic study of multiple neurofibromatosis","author":"Crowe F","year":"1956","unstructured":"Crowe F, Schull W, Neel J. A clinical, pathological, and genetic study of multiple neurofibromatosis. Springfield, IL: Charles C Thomas Publishers; 1956. p. 1\u2013181."},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-11-200606060-00010"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015550510033165"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1977.01640060133020"},{"key":"e_1_3_2_8_2","first-page":"35","article-title":"Early manifestations of neurofibromatosis: diagnosis and management","volume":"8","author":"Riccardi VM","year":"1982","unstructured":"Riccardi VM. Early manifestations of neurofibromatosis: diagnosis and management. Compr Ther 1982;8:35\u201340.","journal-title":"Compr Ther"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1987.01660310085020"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.5070\/D38M71W0WH"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.5070\/D34TP6Q507"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)71917-8"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962012000600012"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/120347540400800505"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5200493"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/088307380401900515"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21418"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.60366"},{"key":"e_1_3_2_19_2","first-page":"65","article-title":"Segmental neurofibromatosis associated with renal angiomyolipomas","volume":"82","author":"Nguyen KT","year":"2008","unstructured":"Nguyen KT, Chiu M. Segmental neurofibromatosis associated with renal angiomyolipomas. Cutis 2008;82:65\u20138.","journal-title":"Cutis"},{"key":"e_1_3_2_20_2","first-page":"399","article-title":"[Segmental neurofibromatosis in children. presentation of 43 patients]","volume":"47","author":"Pascual-Castroviejo I","year":"2008","unstructured":"Pascual-Castroviejo I, Pascual-Pascual SI, Velazquez-Fragua R, . [Segmental neurofibromatosis in children. presentation of 43 patients]. Rev Neurol 2008;47:399\u2013403.","journal-title":"Rev Neurol"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015550510040022"},{"key":"e_1_3_2_22_2","first-page":"43","article-title":"Bilateral segmental neurofibromatosis with gastric carcinoma","volume":"32","author":"Kajimoto A","year":"2007","unstructured":"Kajimoto A, Oiso N, Fukai K, Ishii M. Bilateral segmental neurofibromatosis with gastric carcinoma. Clin Exp Dermatol 2007;32:43\u20134.","journal-title":"Clin Exp Dermatol"}],"container-title":["Journal of Cutaneous Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2013.13116","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.2310\/7750.2013.13116","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.2310\/7750.2013.13116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:50:09Z","timestamp":1777391409000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.2310\/7750.2013.13116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.2310\/7750.2013.13116"],"URL":"https:\/\/doi.org\/10.2310\/7750.2013.13116","relation":{},"ISSN":["1203-4754","1615-7109"],"issn-type":[{"value":"1203-4754","type":"print"},{"value":"1615-7109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}