{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:29:23Z","timestamp":1782602963928,"version":"3.54.5"},"reference-count":21,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Med Surg"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      A permanent, unpleasant atrophic leishmaniasis scar is a potentially disfiguring condition that causes social stigma with limited treatment choices. Fractionated carbon dioxide (CO\n                      <jats:sub>2<\/jats:sub>\n                      ) laser resurfacing is expected to be a safe and effective treatment for leishmaniasis scars.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>\n                      To assess the safety and efficacy of ablative fractional resurfacing (AFR) with a CO\n                      <jats:sub>2<\/jats:sub>\n                      laser for facial leishmaniasis atrophic scars.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Eleven patients (five males, age 18\u201347 years) underwent the fractional CO\n                      <jats:sub>2<\/jats:sub>\n                      laser procedure. The mean duration for scars was 18.3 years. Three to five treatment sessions with the fractional laser eCO2 (10,600 nm, Lutronic Corporation, Gyeonggi-do, Korea) were performed for each patient, at 2-month intervals, under topical anesthesia. Two passes (with tip type 120, density 150 spots\/cm\n                      <jats:sup>2<\/jats:sup>\n                      in static mode, and peak power of 30 watts) were performed on each leishmaniasis scar. Pulse energies ranged between 100 and 140 mJ. Posttreatment improvements in texture, atrophy, and overall satisfaction with appearance were graded on a quartile scale 1 month after the second session and 3 months after the final session. Scar improvement was graded using a 4-point score with a maximum score of 20.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>At the 3-month posttreatment follow-up, all subjects were rated as having at least 50% improvement in texture, atrophy, borders, and overall appearance of scars. The median score of improvement was 18 of 20 (range 11\u201319). Mild postinflammatory hyperpigmentation was the only adverse effect, observed in 18% (2 of 11) of subjects. After the procedure, moderate to severe erythema and edema typically resolved within 24 to 48 hours. No additional adverse effects were observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Fractional CO\n                      <jats:sub>2<\/jats:sub>\n                      resurfacing represents a safe, effective, and well-tolerated potential treatment for atrophic facial leishmaniasis scars in ethnic skin.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2310\/7750.2014.13175","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T15:01:24Z","timestamp":1426086084000},"page":"379-384","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Successful Treatment of Atrophic Facial Leishmaniasis Scars by CO\n                    <sub>2<\/sub>\n                    Fractional Laser"],"prefix":"10.1177","volume":"18","author":[{"given":"Khalid","family":"AlGhamdi","sequence":"first","affiliation":[{"name":"From Department of Dermatology, College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huma","family":"Khurrum","sequence":"additional","affiliation":[{"name":"From Department of Dermatology, College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,11,1]]},"reference":[{"key":"bibr1-7750.2014.13175","first-page":"24","volume":"2","author":"Solish N","year":"1998","journal-title":"Cutan Med Surg"},{"key":"bibr2-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1080\/14764170310001258"},{"key":"bibr3-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1998.tb04060.x"},{"key":"bibr4-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1996.tb00497.x"},{"key":"bibr5-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1997.tb00677.x"},{"key":"bibr6-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20310"},{"key":"bibr7-7750.2014.13175","first-page":"298","volume":"32","author":"Behroozan DS","year":"2006","journal-title":"Dermatol Surg"},{"key":"bibr8-7750.2014.13175","first-page":"295","volume":"33","author":"Alster TS","year":"2007","journal-title":"Dermatol Surg"},{"key":"bibr9-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20468"},{"key":"bibr10-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20254"},{"key":"bibr11-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20659"},{"key":"bibr12-7750.2014.13175","first-page":"103","volume":"69","author":"Babajev KB","year":"1991","journal-title":"Bull World Health Organ"},{"key":"bibr13-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02349.x"},{"key":"bibr14-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2010.09070"},{"key":"bibr15-7750.2014.13175","first-page":"171","volume":"56","author":"Nilforoushzadeh MA","year":"2011","journal-title":"Indian J Dermatol"},{"key":"bibr16-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000049647.65948.50"},{"key":"bibr17-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1159\/000328243"},{"key":"bibr18-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2007.00173.x"},{"key":"bibr19-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2006.00143.x"},{"key":"bibr20-7750.2014.13175","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20048"},{"key":"bibr21-7750.2014.13175","unstructured":"Ortiz A, Elkeeb L, Truitt A, Evaluation of a novel fractional resurfacing device for the treatment of acne scarring [abstract]. 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