{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T01:49:42Z","timestamp":1784166582070,"version":"3.55.0"},"reference-count":54,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec id=\"st1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The purpose of this study was to investigate the diagnostic aspects, contributing conditions, and predictive key factors associated with ectopic eruption of maxillary second molars.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Material and Methods:<\/jats:title>\n                    <jats:p>\n                      This retrospective study evaluated the study models, lateral cephalographs, and panoramic radiographs of 40 adult subjects (20 men, 20 women) with bilateral ectopic eruption and 40 subjects (20 men, 20 women) with normal eruption of the maxillary second molars. Studied variables were analyzed statistically by independent\n                      <jats:italic>t<\/jats:italic>\n                      -tests, univariate and multivariate logistic regression analysis, followed by receiver-operating characteristic analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Tooth widths of bilateral lateral incisors, canines, and premolars were wider in the ectopic group, which resulted in greater arch lengths. The ANB angle and maxillary tuberosity distance (PTV-M1, PTV-M2) were smaller in the ectopic group. The long axes of the maxillary molars showed significant distal inclination in the ectopic group. The multivariate logistic regression analysis showed that three key factors\u2014arch length, ANB angle, and PTV-M1 distance\u2014were significantly associated with ectopic eruption of the second molars. The area under the curve (AUC) was the largest for the combination of the three key factors with an AUC greater than 0.75. PTV-M1 alone was the single factor that showed the strongest association with ectopic eruption (AUC = 0.7363).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>An increase in arch length, decrease in ANB angle, and decrease in maxillary tuberosity distance to the distal aspect of the maxillary first molar (PTV-M1) were the most predictive factors associated with ectopic eruption of maxillary second molars.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2319\/020917-95","type":"journal-article","created":{"date-parts":[[2017,5,3]],"date-time":"2017-05-03T09:36:14Z","timestamp":1493804174000},"page":"583-589","source":"Crossref","is-referenced-by-count":12,"title":["Ectopic eruption of the maxillary second molar: Predictive factors"],"prefix":"10.2319","volume":"87","author":[{"given":"Soonshin","family":"Hwang","sequence":"first","affiliation":[{"name":"Clinical Assistant Professor, Department of Orthodontics, Gangnam Severance Dental Hospital, Institute of Craniofacial Deformity, College of Dentistry, Yonsei University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoon Jeong","family":"Choi","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Orthodontics, Institute of Craniofacial Deformity, College of Dentistry, Yonsei University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Yeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Private Practice, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chooryung","family":"Chung","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Orthodontics, Gangnam Severance Dental Hospital, Institute of Craniofacial Deformity, College of Dentistry, Yonsei University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-Ho","family":"Kim","sequence":"additional","affiliation":[{"name":"Professor and Chair, Department of Orthodontics, Gangnam Severance Dental Hospital, Institute of Craniofacial Deformity, College of Dentistry, Yonsei University, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"key":"i0003-3219-87-4-583-b01","series-title":"Ann Anat","first-page":"353","article-title":"Morphological and clinical considerations of first and second permanent molar eruption disorders","volume":"188","author":"Proff \n              P,","year":"2006","unstructured":"Proff \n              P, \n            \n            \n              Bayerlein \n              T, \n            \n            \n              Fanghanel \n              J, \n            \n            \n              Allegrini \n              S\n              Jr, \n            \n            \n              Gedrange \n              T. \n            \n          \n          Morphological and clinical considerations of first and second permanent molar eruption disorders. Ann Anat. 2006;188:353\u2013361."},{"key":"i0003-3219-87-4-583-b02","series-title":"Oral Surg Oral Med Oral Pathol","first-page":"420","article-title":"The incidence of unerupted permanent teeth and related clinical cases","volume":"59","author":"Grover \n              PS,","year":"1985","unstructured":"Grover \n              PS, \n            \n            \n              Lorton \n              L. \n            \n          \n          The incidence of unerupted permanent teeth and related clinical cases. Oral Surg Oral Med Oral Pathol. 1985;59:420\u2013425."},{"key":"i0003-3219-87-4-583-b03","series-title":"ASDC J Dent Child","first-page":"138","article-title":"The etiology and prevalence of ectopic eruption of the maxillary first permanent molar","volume":"35","author":"Pulver \n              F.","year":"1968","unstructured":"Pulver \n              F. \n            \n          \n          The etiology and prevalence of ectopic eruption of the maxillary first permanent molar. ASDC J Dent Child. 1968;35:138\u2013146."},{"key":"i0003-3219-87-4-583-b04","series-title":"ASDC J Dent Child","first-page":"114","article-title":"Disturbed eruption of the lower second molar: clinical appearance, prevalence, and etiology","volume":"55","author":"Varpio \n              M,","year":"1988","unstructured":"Varpio \n              M, \n            \n            \n              Wellfelt \n              B. \n            \n          \n          Disturbed eruption of the lower second molar: clinical appearance, prevalence, and etiology. ASDC J Dent Child. 1988;55:114\u2013118."},{"key":"i0003-3219-87-4-583-b05","series-title":"Am J Orthod","first-page":"147","article-title":"Ectopic eruption of the maxillary first permanent molar: etiologic factors","volume":"84","author":"Bjerklin \n              K,","year":"1983","unstructured":"Bjerklin \n              K, \n            \n            \n              Kurol \n              J. \n            \n          \n          Ectopic eruption of the maxillary first permanent molar: etiologic factors. Am J Orthod. 1983;84:147\u2013155."},{"key":"i0003-3219-87-4-583-b06","series-title":"J Am Dent Assoc","first-page":"774","article-title":"Impaction of permanent first molar with resorption and space loss in region of deciduous second molar","volume":"35","author":"Cheyne \n              VD,","year":"1947","unstructured":"Cheyne \n              VD, \n            \n            \n              Wessels \n              KE. \n            \n          \n          Impaction of permanent first molar with resorption and space loss in region of deciduous second molar. J Am Dent Assoc. 1947;35:774\u2013787."},{"key":"i0003-3219-87-4-583-b07","series-title":"Angle Orthod","first-page":"422","article-title":"Impaction and retention of second molars: diagnosis, treatment and outcome. A retrospective follow-up study","volume":"79","author":"Magnusson \n              C,","year":"2009","unstructured":"Magnusson \n              C, \n            \n            \n              Kjellberg \n              H. \n            \n          \n          Impaction and retention of second molars: diagnosis, treatment and outcome. A retrospective follow-up study. Angle Orthod. 2009;79:422\u2013427."},{"key":"i0003-3219-87-4-583-b08","series-title":"Angle Orthod","first-page":"773","article-title":"Prevalence of ectopic eruption, impaction, retention and agenesis of the permanent second molar","volume":"77","author":"Bondemark \n              L,","year":"2007","unstructured":"Bondemark \n              L, \n            \n            \n              Tsiopa \n              J. \n            \n          \n          Prevalence of ectopic eruption, impaction, retention and agenesis of the permanent second molar. 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St Louis, MO: Mosby;1999."},{"key":"i0003-3219-87-4-583-b10","series-title":"J Oral Rehabil","first-page":"484","article-title":"Changes in occlusal force and occlusal contact area after active orthodontic treatment: a pilot study using pressure-sensitive sheets","volume":"29","author":"Sultana \n              MH,","year":"2002","unstructured":"Sultana \n              MH, \n            \n            \n              Yamada \n              K, \n            \n            \n              Hanada \n              K. \n            \n          \n          Changes in occlusal force and occlusal contact area after active orthodontic treatment: a pilot study using pressure-sensitive sheets. J Oral Rehabil. 2002;29:484\u2013491."},{"key":"i0003-3219-87-4-583-b11","series-title":"Angle Orthod","first-page":"175","article-title":"Equilibrium theory revisited: factors influencing position of the teeth","volume":"48","author":"Proffit \n              WR.","year":"1978","unstructured":"Proffit \n              WR. \n            \n          \n          Equilibrium theory revisited: factors influencing position of the teeth. Angle Orthod. 1978;48:175\u2013186."},{"key":"i0003-3219-87-4-583-b12","series-title":"J Clin Orthod","first-page":"380","article-title":"The vari-simplex discipline. Part 1. Concept and appliance design","volume":"17","author":"Alexander \n              RG.","year":"1983","unstructured":"Alexander \n              RG. \n            \n          \n          The vari-simplex discipline. Part 1. Concept and appliance design. 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ASDC J Dent Child. 1992;59:228\u2013230."},{"key":"i0003-3219-87-4-583-b15","series-title":"Eur J Orthod","first-page":"309","article-title":"The development of an index of orthodontic treatment priority","volume":"11","author":"Brook \n              PH,","year":"1989","unstructured":"Brook \n              PH, \n            \n            \n              Shaw \n              WC. \n            \n          \n          The development of an index of orthodontic treatment priority. Eur J Orthod. 1989;11:309\u2013320."},{"key":"i0003-3219-87-4-583-b16","series-title":"Am J Orthod","first-page":"554","article-title":"The irregularity index: a quantitative score of mandibular anterior alignment","volume":"68","author":"Little \n              RM.","year":"1975","unstructured":"Little \n              RM. \n            \n          \n          The irregularity index: a quantitative score of mandibular anterior alignment. Am J Orthod. 1975;68:554\u2013563."},{"key":"i0003-3219-87-4-583-b17","series-title":"Eur J Orthod","first-page":"109","article-title":"Dentoalveolar development in subjects with normal occlusion. A longitudinal study between the ages of 5 and 31 years","volume":"31","author":"Thilander \n              B.","year":"2009","unstructured":"Thilander \n              B. \n            \n          \n          Dentoalveolar development in subjects with normal occlusion. A longitudinal study between the ages of 5 and 31 years. Eur J Orthod. 2009;31:109\u2013120."},{"key":"i0003-3219-87-4-583-b18","series-title":"Biometrics","first-page":"837","article-title":"Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach","volume":"44","author":"DeLong \n              ER,","year":"1988","unstructured":"DeLong \n              ER, \n            \n            \n              DeLong \n              DM, \n            \n            \n              Clarke-Pearson \n              DL. \n            \n          \n          Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics. 1988;44:837\u2013845."},{"key":"i0003-3219-87-4-583-b19","series-title":"Funct Orthod","first-page":"34","article-title":"Chewing and occlusal function","volume":"17","author":"Broadbent \n              JM.","year":"2000","unstructured":"Broadbent \n              JM. \n            \n          \n          Chewing and occlusal function. Funct Orthod. 2000;17:34\u201339."},{"key":"i0003-3219-87-4-583-b20","series-title":"N Y State Dent J","first-page":"343","article-title":"The malposed first permanent molar","volume":"35","author":"Herman \n              E.","year":"1969","unstructured":"Herman \n              E. \n            \n          \n          The malposed first permanent molar. N Y State Dent J. 1969;35:343\u2013350."},{"key":"i0003-3219-87-4-583-b21","series-title":"Am J Orthod","first-page":"326","article-title":"A biometric study of tooth size and dental crowding","volume":"79","author":"Doris \n              JM,","year":"1981","unstructured":"Doris \n              JM, \n            \n            \n              Bernard \n              BW, \n            \n            \n              Kuftinec \n              MM, \n            \n            \n              Stom \n              D. \n            \n          \n          A biometric study of tooth size and dental crowding. Am J Orthod. 1981;79:326\u2013336."},{"key":"i0003-3219-87-4-583-b22","series-title":"Prakt Zubn Lek","first-page":"245","article-title":"[Diagnostic method for assessment of possible distalization of the first upper molars]","volume":"38","author":"Jedlickova \n              O.","year":"1990","unstructured":"Jedlickova \n              O. \n            \n          \n          [Diagnostic method for assessment of possible distalization of the first upper molars]. Prakt Zubn Lek. 1990;38:245\u2013249."},{"key":"i0003-3219-87-4-583-b23","series-title":"Acta Odontol. Scand","first-page":"109","article-title":"Sutural growth of the upper face studied by the implant method","volume":"24","author":"Bjork \n              A.","year":"1966","unstructured":"Bjork \n              A. \n            \n          \n          Sutural growth of the upper face studied by the implant method. Acta Odontol. Scand. 1966;24:109\u2013127."},{"key":"i0003-3219-87-4-583-b24","series-title":"Br J Orthod","first-page":"53","article-title":"Growth of the maxilla in three dimensions as revealed radiographically by the implant method","volume":"4","author":"Bjork \n              A,","year":"1977","unstructured":"Bjork \n              A, \n            \n            \n              Skieller \n              V. \n            \n          \n          Growth of the maxilla in three dimensions as revealed radiographically by the implant method. Br J Orthod. 1977;4:53\u201364."},{"key":"i0003-3219-87-4-583-b25","series-title":"Angle Orthod","first-page":"610","article-title":"Ectopic eruption of the maxillary first permanent molar: characteristics and occurrence in growing children","volume":"75","author":"Barberia-Leache \n              E,","year":"2005","unstructured":"Barberia-Leache \n              E, \n            \n            \n              Suarez-Clua \n              MC, \n            \n            \n              Saavedra-Ontiveros \n              D. \n            \n          \n          Ectopic eruption of the maxillary first permanent molar: characteristics and occurrence in growing children. Angle Orthod. 2005;75:610\u2013615."},{"key":"i0003-3219-87-4-583-b26","series-title":"Am J Orthod","first-page":"142","article-title":"Changes in the position of posterior teeth in relation to ruga points","volume":"74","author":"van der Linden \n              FP.","year":"1978","unstructured":"van der Linden \n              FP. \n            \n          \n          Changes in the position of posterior teeth in relation to ruga points. Am J Orthod. 1978;74:142\u2013161."},{"key":"i0003-3219-87-4-583-b27","series-title":"Eur J Orthod","first-page":"249","article-title":"Morphological analysis of cases with ectopic eruption of the maxillary first permanent molar","volume":"5","author":"Canut \n              JA,","year":"1983","unstructured":"Canut \n              JA, \n            \n            \n              Raga \n              C. \n            \n          \n          Morphological analysis of cases with ectopic eruption of the maxillary first permanent molar. Eur J Orthod. 1983;5:249\u2013253."},{"key":"i0003-3219-87-4-583-b01","series-title":"Ann Anat","first-page":"353","article-title":"Morphological and clinical considerations of first and second permanent molar eruption disorders","volume":"188","author":"Proff \n              P,","year":"2006","unstructured":"Proff \n              P, \n            \n            \n              Bayerlein \n              T, \n            \n            \n              Fanghanel \n              J, \n            \n            \n              Allegrini \n              S\n              Jr, \n            \n            \n              Gedrange \n              T. \n            \n          \n          Morphological and clinical considerations of first and second permanent molar eruption disorders. 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St Louis, MO: Mosby;1999."},{"key":"i0003-3219-87-4-583-b10","series-title":"J Oral Rehabil","first-page":"484","article-title":"Changes in occlusal force and occlusal contact area after active orthodontic treatment: a pilot study using pressure-sensitive sheets","volume":"29","author":"Sultana \n              MH,","year":"2002","unstructured":"Sultana \n              MH, \n            \n            \n              Yamada \n              K, \n            \n            \n              Hanada \n              K. \n            \n          \n          Changes in occlusal force and occlusal contact area after active orthodontic treatment: a pilot study using pressure-sensitive sheets. 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Am J Orthod. 1975;68:554\u2013563."},{"key":"i0003-3219-87-4-583-b17","series-title":"Eur J Orthod","first-page":"109","article-title":"Dentoalveolar development in subjects with normal occlusion. A longitudinal study between the ages of 5 and 31 years","volume":"31","author":"Thilander \n              B.","year":"2009","unstructured":"Thilander \n              B. \n            \n          \n          Dentoalveolar development in subjects with normal occlusion. A longitudinal study between the ages of 5 and 31 years. Eur J Orthod. 2009;31:109\u2013120."},{"key":"i0003-3219-87-4-583-b18","series-title":"Biometrics","first-page":"837","article-title":"Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach","volume":"44","author":"DeLong \n              ER,","year":"1988","unstructured":"DeLong \n              ER, \n            \n            \n              DeLong \n              DM, \n            \n            \n              Clarke-Pearson \n              DL. \n            \n          \n          Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics. 1988;44:837\u2013845."},{"key":"i0003-3219-87-4-583-b19","series-title":"Funct Orthod","first-page":"34","article-title":"Chewing and occlusal function","volume":"17","author":"Broadbent \n              JM.","year":"2000","unstructured":"Broadbent \n              JM. \n            \n          \n          Chewing and occlusal function. Funct Orthod. 2000;17:34\u201339."},{"key":"i0003-3219-87-4-583-b20","series-title":"N Y State Dent J","first-page":"343","article-title":"The malposed first permanent molar","volume":"35","author":"Herman \n              E.","year":"1969","unstructured":"Herman \n              E. \n            \n          \n          The malposed first permanent molar. N Y State Dent J. 1969;35:343\u2013350."},{"key":"i0003-3219-87-4-583-b21","series-title":"Am J Orthod","first-page":"326","article-title":"A biometric study of tooth size and dental crowding","volume":"79","author":"Doris \n              JM,","year":"1981","unstructured":"Doris \n              JM, \n            \n            \n              Bernard \n              BW, \n            \n            \n              Kuftinec \n              MM, \n            \n            \n              Stom \n              D. \n            \n          \n          A biometric study of tooth size and dental crowding. 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