{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:10:06Z","timestamp":1789092606225,"version":"build-2803163510"},"reference-count":52,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec id=\"st1\">\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To compare growth-related changes of skeletal and upper airway features of unilateral cleft lip and palate subjects (UCLP) with non-cleft control (NCC) subjects by using lateral cephalograms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>The sample comprised 238 subjects, collected cross-sectionally, divided into 2 groups: 94 with UCLP, and 144 NCC, subdivided into 4 groups according to their growth stages by using cervical vertebral maturation stage (CVMS). The subgroups were defined as early childhood (stage 1), prepubertal (stage 2: CVMS I and II), pubertal (stage 3: CVMS III and IV), and postpubertal (stage 4: CVMS V and VI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The maxilla was more retrognathic at stages 2, 3, and 4 in females with UCLP. The mandible was more retrognathic in UCLP at stage 1 in males, and stages 2 and 3 in females. ANB (angle between NA plane and NB plane) was significantly smaller in UCLP subjects at stage 4 for both sexes. A vertical growth pattern was seen in UCLP subjects except males at stages 2 and 3, and females at stage 2. Posterior airway space was significantly narrower at all stages in males and after stage 1 in females. Middle airway space was significantly wider at all stages in females and after stage 1 in males. Epiglottic airway space was significantly narrower in males at stage 3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Age- and sex-dependent differences in skeletal morphology and upper-airway widths of the UCLP subjects were identified when compared with controls.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2319\/022518-155.1","type":"journal-article","created":{"date-parts":[[2019,1,29]],"date-time":"2019-01-29T13:50:22Z","timestamp":1548769822000},"page":"575-582","source":"Crossref","is-referenced-by-count":13,"title":["Upper airway features of unilateral cleft lip and palate patients in different growth stages"],"prefix":"10.2319","volume":"89","author":[{"given":"Bengisu","family":"Akarsu-Guven","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Orthodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jale","family":"Karakaya","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Biostatistics, Faculty of Medicine, Hacettepe University, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Figen","family":"Ozgur","sequence":"additional","affiliation":[{"name":"Professor, Department of Plastic, Reconstructive and Esthetic Surgery, Faculty of Medicine, Hacettepe University, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muge","family":"Aksu","sequence":"additional","affiliation":[{"name":"Professor, Department of Orthodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"key":"i0003-3219-89-4-575-b01","series-title":"Cleft Palate Craniofac J","first-page":"618","article-title":"Dentocraniofacial morphology of 21 patients with unilateral cleft lip and palate: a cephalometric study","volume":"42","author":"Corbo \n              M,","year":"2005","unstructured":"Corbo \n              M, \n            \n            \n              Dujardin \n              T, \n            \n            \n              de Maertelaer \n              V, \n            \n            \n              Malevez \n              C, \n            \n            \n              Glineur \n              R. \n            \n          \n          Dentocraniofacial morphology of 21 patients with unilateral cleft lip and palate: a cephalometric study. 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Br J Oral Maxillofac Surg. 2006;44:28\u201333."},{"key":"i0003-3219-89-4-575-b03","series-title":"Cleft Palate Craniofac J","first-page":"512","article-title":"Vertical and sagittal growth in patients with unilateral and bilateral cleft lip and palate-a retrospective cephalometric evaluation","volume":"46","author":"Holst \n              AI,","year":"2009","unstructured":"Holst \n              AI, \n            \n            \n              Holst \n              S, \n            \n            \n              Nkenke \n              E, \n            \n            \n              Fenner \n              M, \n            \n            \n              Hirschfelder \n              U. \n            \n          \n          Vertical and sagittal growth in patients with unilateral and bilateral cleft lip and palate-a retrospective cephalometric evaluation. 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Cleft Palate Craniofac J. 2012;49:e75\u201381."},{"key":"i0003-3219-89-4-575-b11","series-title":"Am J Orthod Dentofacial Orthop","first-page":"780","article-title":"Three-dimensional evaluation of the pharyngeal airway volumes in patients affected by unilateral cleft lip and palate","volume":"145","author":"Celikoglu \n              M,","year":"2014","unstructured":"Celikoglu \n              M, \n            \n            \n              Buyuk \n              SK, \n            \n            \n              Sekerci \n              AE, \n            \n            \n              Ucar \n              FI, \n            \n            \n              Cantekin \n              K. \n            \n          \n          Three-dimensional evaluation of the pharyngeal airway volumes in patients affected by unilateral cleft lip and palate. 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Am J Orthod Dentofacial Orthop. 2002;122:189\u2013194."},{"issue":"4 Suppl","key":"i0003-3219-89-4-575-b13","series-title":"Am J Orthod Dentofacial Orthop","first-page":"S92","article-title":"Three-dimensional analysis of the pharyngeal airway morphology in growing Japanese girls with and without cleft lip and palate","volume":"141","author":"Yoshihara \n              M,","year":"2012","unstructured":"Yoshihara \n              M, \n            \n            \n              Terajima \n              M, \n            \n            \n              Yanagita \n              N, \n            \n            et al. \n          Three-dimensional analysis of the pharyngeal airway morphology in growing Japanese girls with and without cleft lip and palate. 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Orthod Craniofac Res. 2004;7:189\u2013197."},{"key":"i0003-3219-89-4-575-b18","series-title":"Am J Orthod Dentofacial Orthop","first-page":"576","article-title":"Growth-related changes of skeletal and upper-airway features in bilateral cleft lip and palate patients","volume":"148","author":"Akarsu-Guven \n              B,","year":"2015","unstructured":"Akarsu-Guven \n              B, \n            \n            \n              Karakaya \n              J, \n            \n            \n              Ozgur \n              F, \n            \n            \n              Aksu \n              M. \n            \n          \n          Growth-related changes of skeletal and upper-airway features in bilateral cleft lip and palate patients. 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Angle Orthod. 2012;82:985\u2013992."},{"key":"i0003-3219-89-4-575-b09","series-title":"Cleft Palate Craniofac J","first-page":"282","article-title":"Nasopharyngeal characteristics in children with cleft lip and palate","volume":"29","author":"Smahel \n              Z,","year":"1992","unstructured":"Smahel \n              Z, \n            \n            \n              M\u00fcllerov\u00e1 \n              I. \n            \n          \n          Nasopharyngeal characteristics in children with cleft lip and palate. 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