{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T15:05:03Z","timestamp":1780067103406,"version":"3.54.0"},"reference-count":60,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess color and fluorescence changes in post-orthodontic white spot lesions (WSLs) using different surface conditioning methods from prior to resin infiltration to a 24-month follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Thirty patients, each with a minimum of four WSLs with ICDAS (International Caries Detection and Assessment System) II code 1 and 2 after bracket debonding were included. After baseline (T0), the lesions were randomly divided into four groups: regular brushing, 15% HCl (hydrogen chloride) gel, 37% H\n                      <jats:sub>3<\/jats:sub>\n                      PO\n                      <jats:sub>4<\/jats:sub>\n                      (phosphoric acid) gel, and Er:YAG (erbium-doped yttrium aluminium garnet) laser. Icon resin infiltration was applied. In the treatment groups, color and fluorescence were reexamined just after the resin infiltration treatment (T1), and after 6 (T2) and 24 months (T3).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no significant fluorescence or color changes between the treatment groups for the different time intervals. The control group showed a significantly lower color change from T0 to T2 and T0 to T3 than all the treatment groups whereas, at T2\u2013T3, the control group showed the greatest improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Resin infiltration caused greater esthetic improvement and more revival of the lost fluorescence than daily brushing. HCl gel, H\n                      <jats:sub>3<\/jats:sub>\n                      PO\n                      <jats:sub>4<\/jats:sub>\n                      gel, and Er:YAG laser are adequate conditioning methods for resin infiltration of post-orthodontic WSLs with ICDAS II code 1 and 2.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2319\/022825-165.1","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T01:16:11Z","timestamp":1770858971000},"page":"311-317","source":"Crossref","is-referenced-by-count":0,"title":["Aesthetic efficacy of resin infiltration on post-orthodontic white spot lesions using different conditioning methods: 24-month randomized control follow-up"],"prefix":"10.2319","volume":"96","author":[{"given":"Emel","family":"Karaman","sequence":"first","affiliation":[{"name":"Professor, Ondokuz May\u0131s University, Faculty of Dentistry, Department of Restorative Dentistry, Samsun, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kubra","family":"Alan Unsal","sequence":"additional","affiliation":[{"name":"Dental Specialist, Private practice, London, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aslihan Zeynep","family":"Oz","sequence":"additional","affiliation":[{"name":"Associate Professor, Ondokuz May\u0131s University, Faculty of Dentistry, Department of Orthodontics, Samsun, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah Alper","family":"Oz","sequence":"additional","affiliation":[{"name":"Professor, \u0130stanbul Galata University, Faculty of Dentistry, Department of Orthodontics, \u0130stanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozlem","family":"Ercin","sequence":"additional","affiliation":[{"name":"Associate Professor, \u0130stanbul Kent University, Faculty of Dentistry, Department of Restorative Dentistry, \u0130stanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"key":"i1945-7103-96-3-311-b01","series-title":"Int J Environ Res Pub Health","first-page":"9460","article-title":"The effect of regime oral-hygiene intervention on the incidence of new white spot lesions in teenagers treated with fixed orthodontic appliances","volume":"17","author":"Kozak","year":"2020","unstructured":"Kozak U,\nS\u0119kowska A,\nCha\u0142as R. The effect of regime oral-hygiene intervention on the incidence of new white spot lesions in teenagers treated with fixed orthodontic appliances. Int J Environ Res Pub Health. 2020;17:9460."},{"key":"i1945-7103-96-3-311-b02","series-title":"Oral Sci Rev","first-page":"100","article-title":"Structure of carious enamel, including the early lesion","volume":"3","author":"Silverstone","year":"1973","unstructured":"Silverstone LM. Structure of carious enamel, including the early lesion. Oral Sci Rev. 1973;3:100\u2013160."},{"key":"i1945-7103-96-3-311-b03","series-title":"Aust Dent J","first-page":"3","article-title":"Minimum intervention dentistry principles and objectives","volume":"58","author":"Walsh","year":"2013","unstructured":"Walsh L,\nBrostek A. Minimum intervention dentistry principles and objectives. Aust Dent J. 2013;58:3\u201316."},{"key":"i1945-7103-96-3-311-b04","series-title":"J Dent","first-page":"1","article-title":"Effectiveness of professional fluorides against enamel white spot lesions during fixed orthodontic treatment: a systematic review and meta-analysis","volume":"82","author":"Sardana","year":"2019","unstructured":"Sardana D,\nZhang J,\nEkambaram M,\nYang Y,\nMcGrath CP,\nYiu CK. Effectiveness of professional fluorides against enamel white spot lesions during fixed orthodontic treatment: a systematic review and meta-analysis. J Dent. 2019;82:1\u201310."},{"key":"i1945-7103-96-3-311-b05","series-title":"Int J Clin Pediatr Dent","first-page":"150","article-title":"Spectrophotometric evaluation of color change in tooth enamel defects using resin infiltrate: An in vivo study","volume":"13","author":"Dogra","year":"2020","unstructured":"Dogra S,\nGoyal V,\nGupta A,\nJoshi S,\nKataria V,\nSaini J et al. Spectrophotometric evaluation of color change in tooth enamel defects using resin infiltrate: An in vivo study. Int J Clin Pediatr Dent. 2020;13:150."},{"key":"i1945-7103-96-3-311-b06","series-title":"Quintessence Int","first-page":"40","article-title":"Closing the gap between oral hygiene and minimally invasive dentistry: a review on the resin infiltration technique of incipient (proximal) enamel lesions","author":"Kielbassa","year":"2009","unstructured":"Kielbassa AM,\nMueller J,\nGernhardt CR. Closing the gap between oral hygiene and minimally invasive dentistry: a review on the resin infiltration technique of incipient (proximal) enamel lesions. Quintessence Int. 2009;40."},{"issue":"9","key":"i1945-7103-96-3-311-b07","series-title":"J Am Dent Assoc","first-page":"997","article-title":"Minimally invasive resin infiltration of arrested white-spot lesions: a randomized clinical trial","volume":"144","author":"Senestraro,","year":"2013","unstructured":"Senestraro, SV,\nCrowe JJ,\nWang M, et al. Minimally invasive resin infiltration of arrested white-spot lesions: a randomized clinical trial. J Am Dent Assoc. 2013;144(9):997\u20131005."},{"key":"i1945-7103-96-3-311-b08","series-title":"Am J Orthod Dentofacial Orthop","first-page":"86","article-title":"Durability of esthetic improvement following Icon resin infiltration of multibracket-induced white spot lesions compared with no therapy over 6 months: a single-center, split-mouth, randomized clinical trial","volume":"144","author":"Knosel","year":"2013","unstructured":"Knosel M,\nEckstein A,\nHelms HJ. Durability of esthetic improvement following Icon resin infiltration of multibracket-induced white spot lesions compared with no therapy over 6 months: a single-center, split-mouth, randomized clinical trial. Am J Orthod Dentofacial Orthop. 2013;144:86\u201396."},{"key":"i1945-7103-96-3-311-b09","series-title":"Angle Orthod","first-page":"33","article-title":"Long-term follow-up of camouflage effects following resin infiltration of post orthodontic white-spot lesions in vivo","volume":"89","author":"Kn\u00f6sel","year":"2019","unstructured":"Kn\u00f6sel M,\nEckstein A,\nHelms HJ. Long-term follow-up of camouflage effects following resin infiltration of post orthodontic white-spot lesions in vivo. Angle Orthod. 2019;89:33\u201339."},{"key":"i1945-7103-96-3-311-b10","series-title":"Caries Res","first-page":"223","article-title":"Surface layer erosion of natural caries lesions with phosphoric and hydrochloric acid gels in preparation for resin infiltration","volume":"41","author":"Meyer-Lueckel","year":"2007","unstructured":"Meyer-Lueckel H,\nParis S,\nKielbassa A. Surface layer erosion of natural caries lesions with phosphoric and hydrochloric acid gels in preparation for resin infiltration. Caries Res. 2007;41:223\u2013230."},{"key":"i1945-7103-96-3-311-b11","series-title":"J Dent","first-page":"103243","article-title":"Evaluation of the value of re-wetting prior to resin infiltration of post-orthodontic caries lesions","volume":"91","author":"Kobbe","year":"2019","unstructured":"Kobbe C,\nFritz U,\nWierichs R,\nMeyer-L\u00fcckel H. Evaluation of the value of re-wetting prior to resin infiltration of post-orthodontic caries lesions. J Dent. 2019;91:103243."},{"key":"i1945-7103-96-3-311-b12","series-title":"Korean J Orthod","first-page":"195","article-title":"Modification of surface pretreatment of white spot lesions to improve the safety and efficacy of resin infiltration","volume":"44","author":"Yim","year":"2014","unstructured":"Yim H-K,\nMin J-H,\nKwon H-K,\nKim B-I. Modification of surface pretreatment of white spot lesions to improve the safety and efficacy of resin infiltration. Korean J Orthod. 2014;44:195\u2013202."},{"key":"i1945-7103-96-3-311-b13","series-title":"Caries Res","first-page":"203","article-title":"Infiltration of natural caries lesions in relation to their activity status and acid pretreatment in vitro","volume":"47","author":"Neuhaus","year":"2013","unstructured":"Neuhaus KW,\nSchlafer S,\nLussi A,\nNyvad B. Infiltration of natural caries lesions in relation to their activity status and acid pretreatment in vitro. Caries Res. 2013;47:203\u2013210."},{"key":"i1945-7103-96-3-311-b14","series-title":"Oper Dent","first-page":"E10","article-title":"Assessing the appearance and fluorescence of resin-infiltrated white spot lesions with caries detection devices","volume":"43","author":"Markowitz","year":"2018","unstructured":"Markowitz K,\nCarey K. Assessing the appearance and fluorescence of resin-infiltrated white spot lesions with caries detection devices. Oper Dent. 2018;43:E10\u2013E18."},{"key":"i1945-7103-96-3-311-b15","series-title":"Clin Oral Investig","first-page":"1945","article-title":"Evaluation of the masking efficacy of caries infiltration in post-orthodontic initial caries lesions: 1-year follow-up","volume":"27","author":"Wierichs","year":"2023","unstructured":"Wierichs RJ,\nAbou-Ayash B,\nKobbe C, et al. Evaluation of the masking efficacy of caries infiltration in post-orthodontic initial caries lesions: 1-year follow-up. Clin Oral Investig. 2023;27:1945\u20131952."},{"key":"i1945-7103-96-3-311-b16","series-title":"Quintessence Int","article-title":"Improving oral health: a short-term split-mouth randomized clinical trial revealing the superiority of resin infiltration over remineralization of white spot lesions","volume":"51","author":"Youssef","year":"2020","unstructured":"Youssef A,\nFarid M,\nZayed M,\nLynch E,\nAlam MK,\nKielbassa AM. Improving oral health: a short-term split-mouth randomized clinical trial revealing the superiority of resin infiltration over remineralization of white spot lesions. Quintessence Int. 2020;51."},{"key":"i1945-7103-96-3-311-b17","series-title":"Oper Dent","first-page":"258","article-title":"Effectiveness and color stability of resin infiltration on demineralized and hypomineralized (MIH) enamel in children: six-month results of a prospective trial","volume":"48","author":"Ozgur","year":"2023","unstructured":"Ozgur B,\nUnverdi GE,\nErtan A,\nCehreli Z. Effectiveness and color stability of resin infiltration on demineralized and hypomineralized (MIH) enamel in children: six-month results of a prospective trial. Oper Dent. 2023;48:258\u2013267."},{"key":"i1945-7103-96-3-311-b18","article-title":"International Caries Detection and Assessment System (ICDAS II)","author":"Committee IC","year":"2009","unstructured":"Committee IC. International Caries Detection and Assessment System (ICDAS II); 2009."},{"key":"i1945-7103-96-3-311-b19","series-title":"Clin Oral Investig","first-page":"5957","article-title":"Comparative evaluation of four treatments for postorthodontic white spot lesions: a randomized controlled trial","volume":"27","author":"Wang","year":"2023","unstructured":"Wang Q,\nZhou Y,\nCui T, et al. Comparative evaluation of four treatments for postorthodontic white spot lesions: a randomized controlled trial. 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J Dent Res. 1955;34:849\u2013853."},{"key":"i1945-7103-96-3-311-b22","series-title":"Caries Res","first-page":"90","article-title":"The effect of brushing time and dentifrice quantity on fluoride delivery in vivo and enamel surface microhardness in situ","volume":"44","author":"Zero","year":"2010","unstructured":"Zero D,\nCreeth J,\nBosma M, et al. The effect of brushing time and dentifrice quantity on fluoride delivery in vivo and enamel surface microhardness in situ. Caries Res. 2010;44:90\u2013100."},{"key":"i1945-7103-96-3-311-b23","series-title":"Caries Res","first-page":"408","article-title":"Infiltration of natural lesions with experimental resins differing in penetration coefficients and ethanol addition","volume":"44","author":"Meyer-Lueckel","year":"2010","unstructured":"Meyer-Lueckel H,\nParis S. Infiltration of natural lesions with experimental resins differing in penetration coefficients and ethanol addition. Caries Res. 2010;44:408\u2013414."},{"key":"i1945-7103-96-3-311-b24","series-title":"Clin Oral Investig","first-page":"4711","article-title":"Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis\u2014a systematic review and meta-analysis","volume":"25","author":"Bourouni","year":"2021","unstructured":"Bourouni S,\nDritsas K,\nKloukos D,\nWierichs RJ. Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis\u2014a systematic review and meta-analysis. Clin Oral Investig. 2021;25:4711\u20134719."},{"key":"i1945-7103-96-3-311-b25","series-title":"J Dent Res","first-page":"662","article-title":"Resin infiltration of natural caries lesions","volume":"86","author":"Paris","year":"2007","unstructured":"Paris S,\nMeyer-Lueckel H,\nKielbassa A. Resin infiltration of natural caries lesions. J Dent Res. 2007;86:662\u2013666."},{"key":"i1945-7103-96-3-311-b26","series-title":"Dent Mater","first-page":"723","article-title":"How much do resin-based dental materials release? A meta-analytical approach","volume":"27","author":"Van Landuyt","year":"2011","unstructured":"Van Landuyt K,\nNawrot T,\nGeebelen B,\nDe Munck J,\nSnauwaert J,\nYoshihara K et al. How much do resin-based dental materials release? A meta-analytical approach. Dent Mater. 2011;27:723\u2013747."},{"key":"i1945-7103-96-3-311-b27","series-title":"J Dent","first-page":"65","article-title":"Surface conditioning of natural enamel caries lesions in deciduous teeth in preparation for resin infiltration","volume":"38","author":"Paris","year":"2010","unstructured":"Paris S,\nD\u00f6rfer CE,\nMeyer-Lueckel H. Surface conditioning of natural enamel caries lesions in deciduous teeth in preparation for resin infiltration. J Dent. 2010;38:65\u201371."},{"key":"i1945-7103-96-3-311-b28","series-title":"J Dent","first-page":"588","article-title":"Modification of surface pre-treatment for resin infiltration to mask natural white spot lesions","volume":"42","author":"Yim","year":"2014","unstructured":"Yim H-K,\nKwon H-K,\nKim B-I. Modification of surface pre-treatment for resin infiltration to mask natural white spot lesions. J Dent. 2014;42:588\u2013594."},{"key":"i1945-7103-96-3-311-b29","series-title":"Eur J Prosthodont Restor Dent","first-page":"73","article-title":"Microtomographic analysis of subsurface enamel and dentine following Er: YAG laser and acid etching","volume":"9","author":"Groth","year":"2001","unstructured":"Groth E,\nMercer C,\nAnderson P. Microtomographic analysis of subsurface enamel and dentine following Er: YAG laser and acid etching. Eur J Prosthodont Restor Dent. 2001;9:73\u201379."},{"key":"i1945-7103-96-3-311-b30","series-title":"Oper Dent","first-page":"443","article-title":"The effect of resin infiltration technique on the calculated color change of demineralized lesions of different severities","volume":"49","author":"Kabeel","year":"2024","unstructured":"Kabeel D,\nNour K,\nSedky R. The effect of resin infiltration technique on the calculated color change of demineralized lesions of different severities. Oper Dent. 2024;49:443\u2013454."},{"key":"i1945-7103-96-3-311-b01","series-title":"Int J Environ Res Pub Health","first-page":"9460","article-title":"The effect of regime oral-hygiene intervention on the incidence of new white spot lesions in teenagers treated with fixed orthodontic appliances","volume":"17","author":"Kozak","year":"2020","unstructured":"Kozak U,\nS\u0119kowska A,\nCha\u0142as R. The effect of regime oral-hygiene intervention on the incidence of new white spot lesions in teenagers treated with fixed orthodontic appliances. Int J Environ Res Pub Health. 2020;17:9460."},{"key":"i1945-7103-96-3-311-b02","series-title":"Oral Sci Rev","first-page":"100","article-title":"Structure of carious enamel, including the early lesion","volume":"3","author":"Silverstone","year":"1973","unstructured":"Silverstone LM. Structure of carious enamel, including the early lesion. Oral Sci Rev. 1973;3:100\u2013160."},{"key":"i1945-7103-96-3-311-b03","series-title":"Aust Dent J","first-page":"3","article-title":"Minimum intervention dentistry principles and objectives","volume":"58","author":"Walsh","year":"2013","unstructured":"Walsh L,\nBrostek A. Minimum intervention dentistry principles and objectives. Aust Dent J. 2013;58:3\u201316."},{"key":"i1945-7103-96-3-311-b04","series-title":"J Dent","first-page":"1","article-title":"Effectiveness of professional fluorides against enamel white spot lesions during fixed orthodontic treatment: a systematic review and meta-analysis","volume":"82","author":"Sardana","year":"2019","unstructured":"Sardana D,\nZhang J,\nEkambaram M,\nYang Y,\nMcGrath CP,\nYiu CK. Effectiveness of professional fluorides against enamel white spot lesions during fixed orthodontic treatment: a systematic review and meta-analysis. J Dent. 2019;82:1\u201310."},{"key":"i1945-7103-96-3-311-b05","series-title":"Int J Clin Pediatr Dent","first-page":"150","article-title":"Spectrophotometric evaluation of color change in tooth enamel defects using resin infiltrate: An in vivo study","volume":"13","author":"Dogra","year":"2020","unstructured":"Dogra S,\nGoyal V,\nGupta A,\nJoshi S,\nKataria V,\nSaini J et al. Spectrophotometric evaluation of color change in tooth enamel defects using resin infiltrate: An in vivo study. Int J Clin Pediatr Dent. 2020;13:150."},{"key":"i1945-7103-96-3-311-b06","series-title":"Quintessence Int","first-page":"40","article-title":"Closing the gap between oral hygiene and minimally invasive dentistry: a review on the resin infiltration technique of incipient (proximal) enamel lesions","author":"Kielbassa","year":"2009","unstructured":"Kielbassa AM,\nMueller J,\nGernhardt CR. Closing the gap between oral hygiene and minimally invasive dentistry: a review on the resin infiltration technique of incipient (proximal) enamel lesions. Quintessence Int. 2009;40."},{"issue":"9","key":"i1945-7103-96-3-311-b07","series-title":"J Am Dent Assoc","first-page":"997","article-title":"Minimally invasive resin infiltration of arrested white-spot lesions: a randomized clinical trial","volume":"144","author":"Senestraro,","year":"2013","unstructured":"Senestraro, SV,\nCrowe JJ,\nWang M, et al. Minimally invasive resin infiltration of arrested white-spot lesions: a randomized clinical trial. J Am Dent Assoc. 2013;144(9):997\u20131005."},{"key":"i1945-7103-96-3-311-b08","series-title":"Am J Orthod Dentofacial Orthop","first-page":"86","article-title":"Durability of esthetic improvement following Icon resin infiltration of multibracket-induced white spot lesions compared with no therapy over 6 months: a single-center, split-mouth, randomized clinical trial","volume":"144","author":"Knosel","year":"2013","unstructured":"Knosel M,\nEckstein A,\nHelms HJ. Durability of esthetic improvement following Icon resin infiltration of multibracket-induced white spot lesions compared with no therapy over 6 months: a single-center, split-mouth, randomized clinical trial. Am J Orthod Dentofacial Orthop. 2013;144:86\u201396."},{"key":"i1945-7103-96-3-311-b09","series-title":"Angle Orthod","first-page":"33","article-title":"Long-term follow-up of camouflage effects following resin infiltration of post orthodontic white-spot lesions in vivo","volume":"89","author":"Kn\u00f6sel","year":"2019","unstructured":"Kn\u00f6sel M,\nEckstein A,\nHelms HJ. Long-term follow-up of camouflage effects following resin infiltration of post orthodontic white-spot lesions in vivo. Angle Orthod. 2019;89:33\u201339."},{"key":"i1945-7103-96-3-311-b10","series-title":"Caries Res","first-page":"223","article-title":"Surface layer erosion of natural caries lesions with phosphoric and hydrochloric acid gels in preparation for resin infiltration","volume":"41","author":"Meyer-Lueckel","year":"2007","unstructured":"Meyer-Lueckel H,\nParis S,\nKielbassa A. Surface layer erosion of natural caries lesions with phosphoric and hydrochloric acid gels in preparation for resin infiltration. Caries Res. 2007;41:223\u2013230."},{"key":"i1945-7103-96-3-311-b11","series-title":"J Dent","first-page":"103243","article-title":"Evaluation of the value of re-wetting prior to resin infiltration of post-orthodontic caries lesions","volume":"91","author":"Kobbe","year":"2019","unstructured":"Kobbe C,\nFritz U,\nWierichs R,\nMeyer-L\u00fcckel H. Evaluation of the value of re-wetting prior to resin infiltration of post-orthodontic caries lesions. J Dent. 2019;91:103243."},{"key":"i1945-7103-96-3-311-b12","series-title":"Korean J Orthod","first-page":"195","article-title":"Modification of surface pretreatment of white spot lesions to improve the safety and efficacy of resin infiltration","volume":"44","author":"Yim","year":"2014","unstructured":"Yim H-K,\nMin J-H,\nKwon H-K,\nKim B-I. Modification of surface pretreatment of white spot lesions to improve the safety and efficacy of resin infiltration. Korean J Orthod. 2014;44:195\u2013202."},{"key":"i1945-7103-96-3-311-b13","series-title":"Caries Res","first-page":"203","article-title":"Infiltration of natural caries lesions in relation to their activity status and acid pretreatment in vitro","volume":"47","author":"Neuhaus","year":"2013","unstructured":"Neuhaus KW,\nSchlafer S,\nLussi A,\nNyvad B. Infiltration of natural caries lesions in relation to their activity status and acid pretreatment in vitro. Caries Res. 2013;47:203\u2013210."},{"key":"i1945-7103-96-3-311-b14","series-title":"Oper Dent","first-page":"E10","article-title":"Assessing the appearance and fluorescence of resin-infiltrated white spot lesions with caries detection devices","volume":"43","author":"Markowitz","year":"2018","unstructured":"Markowitz K,\nCarey K. Assessing the appearance and fluorescence of resin-infiltrated white spot lesions with caries detection devices. Oper Dent. 2018;43:E10\u2013E18."},{"key":"i1945-7103-96-3-311-b15","series-title":"Clin Oral Investig","first-page":"1945","article-title":"Evaluation of the masking efficacy of caries infiltration in post-orthodontic initial caries lesions: 1-year follow-up","volume":"27","author":"Wierichs","year":"2023","unstructured":"Wierichs RJ,\nAbou-Ayash B,\nKobbe C, et al. Evaluation of the masking efficacy of caries infiltration in post-orthodontic initial caries lesions: 1-year follow-up. Clin Oral Investig. 2023;27:1945\u20131952."},{"key":"i1945-7103-96-3-311-b16","series-title":"Quintessence Int","article-title":"Improving oral health: a short-term split-mouth randomized clinical trial revealing the superiority of resin infiltration over remineralization of white spot lesions","volume":"51","author":"Youssef","year":"2020","unstructured":"Youssef A,\nFarid M,\nZayed M,\nLynch E,\nAlam MK,\nKielbassa AM. Improving oral health: a short-term split-mouth randomized clinical trial revealing the superiority of resin infiltration over remineralization of white spot lesions. Quintessence Int. 2020;51."},{"key":"i1945-7103-96-3-311-b17","series-title":"Oper Dent","first-page":"258","article-title":"Effectiveness and color stability of resin infiltration on demineralized and hypomineralized (MIH) enamel in children: six-month results of a prospective trial","volume":"48","author":"Ozgur","year":"2023","unstructured":"Ozgur B,\nUnverdi GE,\nErtan A,\nCehreli Z. Effectiveness and color stability of resin infiltration on demineralized and hypomineralized (MIH) enamel in children: six-month results of a prospective trial. Oper Dent. 2023;48:258\u2013267."},{"key":"i1945-7103-96-3-311-b18","article-title":"International Caries Detection and Assessment System (ICDAS II)","author":"Committee IC","year":"2009","unstructured":"Committee IC. International Caries Detection and Assessment System (ICDAS II); 2009."},{"key":"i1945-7103-96-3-311-b19","series-title":"Clin Oral Investig","first-page":"5957","article-title":"Comparative evaluation of four treatments for postorthodontic white spot lesions: a randomized controlled trial","volume":"27","author":"Wang","year":"2023","unstructured":"Wang Q,\nZhou Y,\nCui T, et al. Comparative evaluation of four treatments for postorthodontic white spot lesions: a randomized controlled trial. Clin Oral Investig. 2023;27:5957\u20135968."},{"key":"i1945-7103-96-3-311-b20","series-title":"Eur J Orthod","first-page":"595","article-title":"Colour improvement and stability of white spot lesions following infiltration, micro-abrasion, or fluoride treatments in vitro","volume":"36","author":"Yetkiner","year":"2014","unstructured":"Yetkiner E,\nWegehaupt F,\nWiegand A,\nAttin R,\nAttin T. Colour improvement and stability of white spot lesions following infiltration, micro-abrasion, or fluoride treatments in vitro. Eur J Orthod. 2014;36:595\u2013602."},{"key":"i1945-7103-96-3-311-b21","series-title":"J Dent Res","first-page":"849","article-title":"A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces","volume":"34","author":"Buonocore","year":"1955","unstructured":"Buonocore MG. A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. 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