{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:16:44Z","timestamp":1780481804163,"version":"3.54.1"},"reference-count":58,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To propose a better statistical method of predicting postsurgery soft tissue response in Class II patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>The subjects comprise 80 patients who had undergone surgical correction of severe Class II malocclusions. Using 228 predictor and 64 soft tissue response variables, we applied two multivariate methods of forming prediction equations, the conventional ordinary least squares (OLS) method and the partial least squares (PLS) method. After fitting the equation, the bias and a mean absolute prediction error were calculated. To evaluate the predictive performance of the prediction equations, a leave-one-out cross-validation method was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The multivariate PLS method provided a significantly more accurate prediction than the conventional OLS method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The multivariate PLS method was more satisfactory than the OLS method in accurately predicting the soft tissue profile change after surgical correction of severe Class II malocclusions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2319\/050313-338.1","type":"journal-article","created":{"date-parts":[[2013,8,8]],"date-time":"2013-08-08T13:46:41Z","timestamp":1375969601000},"page":"322-328","source":"Crossref","is-referenced-by-count":12,"title":["A better statistical method of predicting postsurgery soft tissue response in Class II patients"],"prefix":"10.2319","volume":"84","author":[{"given":"Ho-Jin","family":"Lee","sequence":"first","affiliation":[{"name":"Graduate Student, Department of Orthodontics, Seoul National University School of Dentistry & Dental Research Institute, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee-Yeon","family":"Suh","sequence":"additional","affiliation":[{"name":"Graduate Student, Department of Orthodontics, Seoul National University School of Dentistry & Dental Research Institute, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Sik","family":"Lee","sequence":"additional","affiliation":[{"name":"Graduate Student, Department of Orthodontics, Seoul National University School of Dentistry & Dental Research Institute, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-Jae","family":"Lee","sequence":"additional","affiliation":[{"name":"Professor and Chair, Department of Orthodontics, Seoul National University School of Dentistry & Dental Research Institute, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Donatelli","sequence":"additional","affiliation":[{"name":"Clinical Assistant Professor, Department of Orthodontics, University of Florida College of Dentistry, Gainesville, Fla"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calogero","family":"Dolce","sequence":"additional","affiliation":[{"name":"Professor and Chair, Department of Orthodontics, University of Florida College of Dentistry, Gainesville, Fla"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy T.","family":"Wheeler","sequence":"additional","affiliation":[{"name":"Professor, Department of Orthodontics, University of Florida College of Dentistry, Gainesville, Fla"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"key":"i0003-3219-84-2-322-b01","series-title":"J Oral Maxillofac Surg","first-page":"e553","article-title":"A more accurate method of predicting soft tissue changes after mandibular setback surgery","volume":"70","author":"Suh\n              HY,","year":"2012","unstructured":"Suh\n              HY, \n            \n              Lee\n              SJ, \n            \n              Lee\n              YS, \n            et al\n          . A more accurate method of predicting soft tissue changes after mandibular setback surgery. J Oral Maxillofac Surg. 2012;70:e553\u2013e562."},{"key":"i0003-3219-84-2-322-b02","series-title":"J Oral Maxillofac Surg","first-page":"1260","article-title":"Soft tissue profile changes after bilateral sagittal split osteotomy for mandibular advancement: a systematic review","volume":"68","author":"Joss\n              CU,","year":"2010","unstructured":"Joss\n              CU, \n            \n              Joss-Vassalli\n              IM, \n            \n              Kiliaridis\n              S, \n            \n              Kuijpers-Jagtman\n              AM. \n          \n          Soft tissue profile changes after bilateral sagittal split osteotomy for mandibular advancement: a systematic review. J Oral Maxillofac Surg. 2010;68:1260\u20131269."},{"key":"i0003-3219-84-2-322-b03","series-title":"Semin Orthod","first-page":"161","article-title":"Soft-tissue changes related to mandibular advancement surgery","volume":"15","author":"McCollum\n              AGH,","year":"2009","unstructured":"McCollum\n              AGH, \n            \n              Gardener\n              GJM, \n            \n              Evans\n              WG, \n            \n              Becker\n              PJ. \n          \n          Soft-tissue changes related to mandibular advancement surgery. Semin Orthod. 2009;15:161\u2013171."},{"key":"i0003-3219-84-2-322-b04","series-title":"Semin Orthod","first-page":"185","article-title":"Sagittal soft-tissue changes of the lower lip and chin associated with surgical maxillary impaction and consequent mandibular autorotation","volume":"15","author":"Ksiezycki-Ostoya\n              BK,","year":"2009","unstructured":"Ksiezycki-Ostoya\n              BK, \n            \n              McCollum\n              AGH, \n            \n              Becker\n              PJ. \n          \n          Sagittal soft-tissue changes of the lower lip and chin associated with surgical maxillary impaction and consequent mandibular autorotation. Semin Orthod. 2009;15:185\u2013195."},{"key":"i0003-3219-84-2-322-b05","series-title":"Eur J Orthod","first-page":"359","article-title":"Soft tissue profile changes after vertical ramus osteotomy","volume":"30","author":"Naoumova\n              J,","year":"2008","unstructured":"Naoumova\n              J, \n            \n              Soderfeldt\n              B, \n            \n              Lindman\n              R. \n          \n          Soft tissue profile changes after vertical ramus osteotomy. 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Am J Orthod Dentofacial Orthop. 2006;130:8\u201317."},{"key":"i0003-3219-84-2-322-b07","series-title":"Am J Orthod Dentofacial Orthop","first-page":"249","article-title":"Five-year outcome and predictability of soft tissue profiles when wire or rigid fixation is used in mandibular advancement surgery","volume":"124","author":"Dolce\n              C,","year":"2003","unstructured":"Dolce\n              C, \n            \n              Hatch\n              JP, \n            \n              Van Sickels\n              JE, \n            \n              Rugh\n              JD. \n          \n          Five-year outcome and predictability of soft tissue profiles when wire or rigid fixation is used in mandibular advancement surgery. Am J Orthod Dentofacial Orthop. 2003;124:249\u2013256."},{"key":"i0003-3219-84-2-322-b08","series-title":"J Craniofac Surg","first-page":"593","article-title":"How the lower face soft tissue changes after mandibular advancement or setback","volume":"19","author":"Alves\n              PV,","year":"2008","unstructured":"Alves\n              PV, \n            \n              Mazucheli\n              J, \n            \n              Vogel\n              CJ, \n            \n              Bolognese\n              AM. \n          \n          How the lower face soft tissue changes after mandibular advancement or setback. J Craniofac Surg. 2008;19:593\u2013598."},{"key":"i0003-3219-84-2-322-b09","series-title":"Am J Orthod Dentofacial Orthop","first-page":"657","article-title":"Prediction of soft-tissue changes after mandibular advancement surgery with an equation developed with multivariable regression","volume":"134","author":"Kneafsey\n              LC,","year":"2008","unstructured":"Kneafsey\n              LC, \n            \n              Cunningham\n              SJ, \n            \n              Petrie\n              A, \n            \n              Hutton\n              TJ. \n          \n          Prediction of soft-tissue changes after mandibular advancement surgery with an equation developed with multivariable regression. Am J Orthod Dentofacial Orthop. 2008;134:657\u2013664."},{"key":"i0003-3219-84-2-322-b10","series-title":"J Chemometr","first-page":"320","article-title":"Computational performance and cross-validation error precision of five PLS algorithms using designed and real data sets","volume":"24","author":"Martins\n              JPA,","year":"2010","unstructured":"Martins\n              JPA, \n            \n              Teofilo\n              RF, \n            \n              Ferreira\n              MMC. \n          \n          Computational performance and cross-validation error precision of five PLS algorithms using designed and real data sets. J Chemometr. 2010;24:320\u2013332."},{"key":"i0003-3219-84-2-322-b11","series-title":"Pharm Res","first-page":"1989","article-title":"Quantitative structure-activity relationship and quantitative structure-pharmacokinetics relationship of 1,4-dihydropyridines and pyridines as multidrug resistance modulators","volume":"22","author":"Zhou\n              XF,","year":"2005","unstructured":"Zhou\n              XF, \n            \n              Shao\n              Q, \n            \n              Coburn\n              RA, \n            \n              Morris\n              ME. \n          \n          Quantitative structure-activity relationship and quantitative structure-pharmacokinetics relationship of 1,4-dihydropyridines and pyridines as multidrug resistance modulators. Pharm Res. 2005;22:1989\u20131996."},{"key":"i0003-3219-84-2-322-b12","series-title":"Chemometric With R: Multivariate Data Analysis in the Natural Sciences and Life Sciences. 1st ed","author":"Wehrens\n              R.","year":"2011","unstructured":"Wehrens\n              R. \n          \n          Chemometric With R: Multivariate Data Analysis in the Natural Sciences and Life Sciences. 1st ed. Heidelberg: Springer; 2011."},{"key":"i0003-3219-84-2-322-b13","series-title":"The Elements of Statistical Learning. Data Mining, Inference, and Prediction. 2nd ed","author":"Hastie\n              T,","year":"2009","unstructured":"Hastie\n              T, \n            \n              Tibshirani\n              R, \n            \n              Friedman\n              J. \n          \n          The Elements of Statistical Learning. Data Mining, Inference, and Prediction. 2nd ed. New York: Springer Verlag; 2009."},{"key":"i0003-3219-84-2-322-b14","series-title":"Wiley Interdiscip Rev Comput Stat","first-page":"97","article-title":"Partial least squares regression and projection on latent structure regression (PLS regression)","volume":"2","author":"Abdi\n              H.","year":"2010","unstructured":"Abdi\n              H. \n          \n          Partial least squares regression and projection on latent structure regression (PLS regression). 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Pharm Res. 2005;22:1989\u20131996."},{"key":"i0003-3219-84-2-322-b12","series-title":"Chemometric With R: Multivariate Data Analysis in the Natural Sciences and Life Sciences. 1st ed","author":"Wehrens\n              R.","year":"2011","unstructured":"Wehrens\n              R. \n          \n          Chemometric With R: Multivariate Data Analysis in the Natural Sciences and Life Sciences. 1st ed. Heidelberg: Springer; 2011."},{"key":"i0003-3219-84-2-322-b13","series-title":"The Elements of Statistical Learning. Data Mining, Inference, and Prediction. 2nd ed","author":"Hastie\n              T,","year":"2009","unstructured":"Hastie\n              T, \n            \n              Tibshirani\n              R, \n            \n              Friedman\n              J. \n          \n          The Elements of Statistical Learning. Data Mining, Inference, and Prediction. 2nd ed. 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