{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:30:36Z","timestamp":1784647836266,"version":"3.55.0"},"reference-count":78,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec id=\"st1\">\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To assess alterations in respiratory muscle strength and inspiratory and expiratory peak flow, as well as skeletal and dental changes in patients diagnosed with transverse maxillary deficiency before and after microimplant-assisted rapid maxillary expansion (MARPE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Twenty patients (13 female and 7 male) were assessed by respiratory tests in three different periods: T0 initial, T1 immediately after expansion, and T2 after 5 months. Tests included: maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP), oral expiratory peak flow, and inspiratory nasal flow. Cone-beam computed tomography measurements were performed in the maxillary arch, nasal cavity, and airway before and immediately after expansion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      There was a significant increase in MIP between T0 and T2 and MEP between T0 and T1 (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.05). Oral and nasal peak flow increased immediately after and 5 months later, especially in patients with initial signs of airway obstruction (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.05). In addition, after expansion there was a significant enlargement of the nasal cavity, alveolar bone, and interdental widths at the premolar and molar region. Molars tipped buccally (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.05) but no difference was found in premolar inclination. MARPE increased airway volume significantly.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st4\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Skeletal changes promoted by MARPE directly affected airway volume, resulting in a significant improvement in muscle strength and nasal and oral peak flow.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2319\/070518-504.1","type":"journal-article","created":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T11:52:45Z","timestamp":1553169165000},"page":"713-720","source":"Crossref","is-referenced-by-count":45,"title":["Assessment of respiratory muscle strength and airflow before and after microimplant-assisted rapid palatal expansion"],"prefix":"10.2319","volume":"89","author":[{"given":"Camilla Juliana","family":"Storto","sequence":"first","affiliation":[{"name":"Student, Department of Postgraduate Orthodontics, S\u00e3o Leopoldo Mandic Institute and Research Center, Campinas, SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aguinaldo Silva","family":"Garcez","sequence":"additional","affiliation":[{"name":"Professor, Department of Microbiology, S\u00e3o Leopoldo Mandic Institute and Research Center, Campinas, SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Professor and Department Chair, Department of Postgraduate Orthodontics, S\u00e3o Leopoldo Mandic Institute and Research Center, Campinas, SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla Garcez","family":"Cusmanich","sequence":"additional","affiliation":[{"name":"Professor, Department of Graduate Physical Therapy, University of Taubat\u00e9, Taubat\u00e9, SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Islam","family":"Elkenawy","sequence":"additional","affiliation":[{"name":"MSc student and Resident, Section of Orthodontics, School of Dentistry, University of California Los Angeles, Los Angeles, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won","family":"Moon","sequence":"additional","affiliation":[{"name":"Professor and Program Director, Section of Orthodontics, School of Dentistry, University of California Los Angeles, Los Angeles, CA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selly Sayuri","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Professor, Department of Postgraduate Orthodontics, S\u00e3o Leopoldo Mandic Institute and Research Center, Campinas, SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"issue":"3","key":"i0003-3219-89-5-713-b01","series-title":"Eur J Orthod","first-page":"173","article-title":"Longitudinal study and cost-benefit analysis of the effect of early treatment of posterior cross-bites in the primary dentition","volume":"14","author":"Kurol \n              J,","year":"1992","unstructured":"Kurol \n              J, \n            \n            \n              Berglund \n              L. \n            \n          \n          Longitudinal study and cost-benefit analysis of the effect of early treatment of posterior cross-bites in the primary dentition. 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Respir Care. 2009;54(10):1348\u20131359."},{"issue":"1","key":"i0003-3219-89-5-713-b08","series-title":"MedicalExpress","first-page":"1","article-title":"Evaluation of the effect of learning on the full extent of inspiratory and expiratory pressure in healthy adults","volume":"3","author":"Giuliani \n              BB,","year":"2016","unstructured":"Giuliani \n              BB, \n            \n            \n              Olavo \n              GC, \n            \n            \n              Machado \n              KS, \n            \n            \n              Abreu \n              LC, \n            \n            \n              Valenti \n              VE, \n            \n            \n              Raimundo \n              RD. \n            \n          \n          Evaluation of the effect of learning on the full extent of inspiratory and expiratory pressure in healthy adults. MedicalExpress. 2016;3(1)1\u20135."},{"issue":"3","key":"i0003-3219-89-5-713-b09","series-title":"J Bras Pneumol","first-page":"306","article-title":"Novos valores de refer\u00eancia para press\u00f5es respirat\u00f3rias m\u00e1ximas na popula\u00e7\u00e3o brasileira","volume":"36","author":"Costa \n              D,","year":"2010","unstructured":"Costa \n              D, \n            \n            \n              Gon\u00e7alves \n              HA, \n            \n            \n              Lima \n              LP, \n            \n            \n              Ike \n              D, \n            \n            \n              Cancelliero \n              KM, \n            \n            \n              Montebelo \n              MIL. \n            \n          \n          Novos valores de refer\u00eancia para press\u00f5es respirat\u00f3rias m\u00e1ximas na popula\u00e7\u00e3o brasileira. 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Dental Press J Orthod. 2013;18(3):12\u201328."},{"issue":"5","key":"i0003-3219-89-5-713-b11","series-title":"Angle Orthod","first-page":"713","article-title":"Nonsurgical miniscrew-assisted rapid maxillary expansion results in acceptable stability in young adults","volume":"86","author":"Choi \n              SH,","year":"2016","unstructured":"Choi \n              SH, \n            \n            \n              Shi \n              KK, \n            \n            \n              Cha \n              JY, \n            \n            \n              Park \n              YC, \n            \n            \n              Lee \n              KJ. \n            \n          \n          Nonsurgical miniscrew-assisted rapid maxillary expansion results in acceptable stability in young adults. Angle Orthod. 2016;86(5):713\u2013720."},{"issue":"4","key":"i0003-3219-89-5-713-b12","series-title":"Dental Press J Orthod","first-page":"17","article-title":"Miniscrew-assisted rapid palatal expander (MARPE): the quest for pure orthopedic movement","volume":"21","author":"Suzuki \n              H,","year":"2016","unstructured":"Suzuki \n              H, \n            \n            \n              Moon \n              W, \n            \n            \n              Previdente \n              LH, \n            \n            \n              Suzuki \n              SS, \n            \n            \n              Garcez \n              AS, \n            \n            \n              Consolaro \n              A. \n            \n          \n          Miniscrew-assisted rapid palatal expander (MARPE): the quest for pure orthopedic movement. 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Prog Orthod. 2014;15(52):1\u201315."},{"issue":"2","key":"i0003-3219-89-5-713-b14","series-title":"Korean J Orthod","first-page":"77","article-title":"Skeletal and dentoalveolar changes after miniscrew-assisted rapid palatal expansion in young adults: A cone-beam computed tomography study","volume":"47","author":"Park \n              JJ,","year":"2017","unstructured":"Park \n              JJ, \n            \n            \n              Park \n              YC, \n            \n            \n              Lee \n              KJ, \n            \n            \n              Cha \n              JY, \n            \n            \n              Tahk \n              JH, \n            \n            \n              Choi \n              YJ. \n            \n          \n          Skeletal and dentoalveolar changes after miniscrew-assisted rapid palatal expansion in young adults: A cone-beam computed tomography study. Korean J Orthod. 2017;47(2):77\u201386."},{"issue":"4","key":"i0003-3219-89-5-713-b15","series-title":"Angle Orthod","first-page":"435","article-title":"Assessment of changes in the nasal airway after nonsurgical miniscrew-assisted rapid maxillary expansion in young adults","volume":"88","author":"Kim \n              SY,","year":"2018","unstructured":"Kim \n              SY, \n            \n            \n              Park \n              YC, \n            \n            \n              Lee \n              KJ, \n            \n            et al. \n          Assessment of changes in the nasal airway after nonsurgical miniscrew-assisted rapid maxillary expansion in young adults. 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Angle Orthod. 2014;84(2):265\u2013273."},{"issue":"5","key":"i0003-3219-89-5-713-b32","series-title":"Int J Oral Maxillofac Surg","first-page":"681","article-title":"Volumetric upper airway assessment in patients with transverse maxillary deficiency after surgically assisted rapid maxillary expansion","volume":"43","author":"Pereira-Filho \n              VA,","year":"2014","unstructured":"Pereira-Filho \n              VA, \n            \n            \n              Monnazzi \n              MS, \n            \n            \n              Gabrielli \n              MAC, \n            \n            et al. \n          Volumetric upper airway assessment in patients with transverse maxillary deficiency after surgically assisted rapid maxillary expansion. Int J Oral Maxillofac Surg. 2014;43(5):681\u2013686."},{"issue":"5","key":"i0003-3219-89-5-713-b33","series-title":"Dental Press J Orthod","first-page":"79","article-title":"Transverse effects on the nasomaxillary complex one year after rapid maxillary expansion as the only intervention: A controlled study","volume":"19","author":"Baratieri \n              CL,","year":"2014","unstructured":"Baratieri \n              CL, \n            \n            \n              Alves \n              Jr\n              M, \n            \n            \n              Mattos \n              CT, \n            \n            \n              Lau \n              GWT, \n            \n            \n              Nojima \n              LI, \n            \n            \n              Souza \n              MMG. \n            \n          \n          Transverse effects on the nasomaxillary complex one year after rapid maxillary expansion as the only intervention: A controlled study. 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Int J Oral Maxillofac Surg. 2012;41(9):1120\u20131126."},{"issue":"3","key":"i0003-3219-89-5-713-b36","series-title":"Eur J Orthod","first-page":"281","article-title":"Effects on nasal airflow and resistance using two different RME appliances: a randomized controlled trial","volume":"40","author":"Bazargani \n              F,","year":"2017","unstructured":"Bazargani \n              F, \n            \n            \n              Magnuson \n              A, \n            \n            \n              Ludwig \n              B. \n            \n          \n          Effects on nasal airflow and resistance using two different RME appliances: a randomized controlled trial. 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Angle Orthod. 2018;88:649\u2013664."},{"issue":"5","key":"i0003-3219-89-5-713-b03","series-title":"Rev. CEFAC","first-page":"1432","article-title":"Nasal aeration and respiratory muscle strength in mouth breathers'' children","volume":"17","author":"Cunha \n              RA,","year":"2015","unstructured":"Cunha \n              RA, \n            \n            \n              Cunha \n              DA, \n            \n            \n              Bezerra \n              LA, \n            \n            et al. \n          Nasal aeration and respiratory muscle strength in mouth breathers'' children. Rev. 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Respir Care. 2009;54(10):1348\u20131359."},{"issue":"1","key":"i0003-3219-89-5-713-b08","series-title":"MedicalExpress","first-page":"1","article-title":"Evaluation of the effect of learning on the full extent of inspiratory and expiratory pressure in healthy adults","volume":"3","author":"Giuliani \n              BB,","year":"2016","unstructured":"Giuliani \n              BB, \n            \n            \n              Olavo \n              GC, \n            \n            \n              Machado \n              KS, \n            \n            \n              Abreu \n              LC, \n            \n            \n              Valenti \n              VE, \n            \n            \n              Raimundo \n              RD. \n            \n          \n          Evaluation of the effect of learning on the full extent of inspiratory and expiratory pressure in healthy adults. 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Prog Orthod. 2014;15(52):1\u201315."},{"issue":"2","key":"i0003-3219-89-5-713-b14","series-title":"Korean J Orthod","first-page":"77","article-title":"Skeletal and dentoalveolar changes after miniscrew-assisted rapid palatal expansion in young adults: A cone-beam computed tomography study","volume":"47","author":"Park \n              JJ,","year":"2017","unstructured":"Park \n              JJ, \n            \n            \n              Park \n              YC, \n            \n            \n              Lee \n              KJ, \n            \n            \n              Cha \n              JY, \n            \n            \n              Tahk \n              JH, \n            \n            \n              Choi \n              YJ. \n            \n          \n          Skeletal and dentoalveolar changes after miniscrew-assisted rapid palatal expansion in young adults: A cone-beam computed tomography study. Korean J Orthod. 2017;47(2):77\u201386."},{"issue":"4","key":"i0003-3219-89-5-713-b15","series-title":"Angle Orthod","first-page":"435","article-title":"Assessment of changes in the nasal airway after nonsurgical miniscrew-assisted rapid maxillary expansion in young adults","volume":"88","author":"Kim \n              SY,","year":"2018","unstructured":"Kim \n              SY, \n            \n            \n              Park \n              YC, \n            \n            \n              Lee \n              KJ, \n            \n            et al. \n          Assessment of changes in the nasal airway after nonsurgical miniscrew-assisted rapid maxillary expansion in young adults. Angle Orthod. 2018;88(4):435\u2013441."},{"issue":"34","key":"i0003-3219-89-5-713-b16","series-title":"Prog Orthod","first-page":"1","article-title":"Changes in the midpalatal and pterygopalatine sutures induced by micro-implant-supported skeletal expander, analyzed with a novel 3D method based on CBCT imaging","volume":"18","author":"Cantarella \n              D,","year":"2017","unstructured":"Cantarella \n              D, \n            \n            \n              Dominguez-Mompell \n              R, \n            \n            \n              Mallya \n              SM, \n            \n            et al. \n          Changes in the midpalatal and pterygopalatine sutures induced by micro-implant-supported skeletal expander, analyzed with a novel 3D method based on CBCT imaging. Prog Orthod. 2017;18(34):1\u201312."},{"issue":"4","key":"i0003-3219-89-5-713-b17","series-title":"Angle Orthod","first-page":"316","article-title":"An improved version of the cervical vertebral maturation (CVM) method for the assessment of mandibular growth","volume":"72","author":"Baccetti \n              T,","year":"2002","unstructured":"Baccetti \n              T, \n            \n            \n              Franchi \n              L, \n            \n            \n              Mcnamara \n              Jr\n              J. \n            \n          \n          An improved version of the cervical vertebral maturation (CVM) method for the assessment of mandibular growth. Angle Orthod. 2002;72(4):316\u2013323."},{"issue":"5","key":"i0003-3219-89-5-713-b18","series-title":"Am J Orthod Dentofac Orthop","first-page":"716","article-title":"Microimplant-assisted rapid palatal expansion appliance to orthopedically correct transverse maxillary deficiency in an adult","volume":"149","author":"Carlson \n              C,","year":"2016","unstructured":"Carlson \n              C, \n            \n            \n              Sung \n              J, \n            \n            \n              McComb \n              RW, \n            \n            \n              MacHado \n              AW, \n            \n            \n              Moon \n              W. \n            \n          \n          Microimplant-assisted rapid palatal expansion appliance to orthopedically correct transverse maxillary deficiency in an adult. Am J Orthod Dentofac Orthop. 2016;149(5):716\u2013728."},{"issue":"1","key":"i0003-3219-89-5-713-b19","series-title":"Dental Press J Orthod","first-page":"110","article-title":"Non-surgical treatment of transverse deficiency in adults using microimplant-assisted rapid palatal expansion (MARPE)","volume":"22","author":"Brunetto \n              DP,","year":"2017","unstructured":"Brunetto \n              DP, \n            \n            \n              Sant'Anna \n              EF, \n            \n            \n              Machado \n              AW, \n            \n            \n              Moon \n              W. \n            \n          \n          Non-surgical treatment of transverse deficiency in adults using microimplant-assisted rapid palatal expansion (MARPE). 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Am J Orthod Dentofac Orthop. 2008;134(1):16\u201321."},{"issue":"1","key":"i0003-3219-89-5-713-b26","series-title":"Surgeon","first-page":"1","article-title":"Does rapid maxillary expansion affect nasopharyngeal airway? A prospective Cone Beam Computerised Tomography (CBCT) based study","volume":"16","author":"Almuzian \n              M,","year":"2018","unstructured":"Almuzian \n              M, \n            \n            \n              Ju \n              X, \n            \n            \n              Almukhtar \n              A, \n            \n            \n              Ayoub \n              A, \n            \n            \n              Al-Muzian \n              L, \n            \n            \n              McDonald \n              JP. \n            \n          \n          Does rapid maxillary expansion affect nasopharyngeal airway? A prospective Cone Beam Computerised Tomography (CBCT) based study. Surgeon. 2018;16(1):1\u201311."},{"key":"i0003-3219-89-5-713-b27","series-title":"Am J Orthod Dentofac Orthop","first-page":"79","article-title":"Effects of bonded rapid palatal expansion on the transverse dimensions of the maxilla: A cone-beam computed tomography study","volume":"137","author":"Christie \n              KF,","year":"2010","unstructured":"Christie \n              KF, \n            \n            \n              Boucher \n              N, \n            \n            \n              Chung \n              CH. \n            \n          \n          Effects of bonded rapid palatal expansion on the transverse dimensions of the maxilla: A cone-beam computed tomography study. 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Angle Orthod. 2015;85(2):253\u2013262."},{"issue":"5","key":"i0003-3219-89-5-713-b30","series-title":"Eur J Orthod","first-page":"556","article-title":"Comparison of short-term effects of mini-implant-supported maxillary expansion appliance with two conventional expansion protocols","volume":"37","author":"Yilmaz \n              A,","year":"2015","unstructured":"Yilmaz \n              A, \n            \n            \n              Arman-\u00d6z\u00e7lrplcl \n              A, \n            \n            \n              Erken \n              S, \n            \n            \n              Polat-\u00d6zsoy \n              \u00d6. \n            \n          \n          Comparison of short-term effects of mini-implant-supported maxillary expansion appliance with two conventional expansion protocols. 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