{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:55:14Z","timestamp":1781744114490,"version":"3.54.5"},"reference-count":54,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the predictability of Invisalign First in achieving planned dental arch expansion in mixed dentition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Following PRISMA guidelines and a PROSPERO-registered protocol (CRD420251083929), electronic databases were searched up to July 2025. Eligible studies included data evaluating Invisalign First for dental arch expansion in mixed dentition. Predictability, defined as ratio of achieved to planned expansion, was the primary outcome. Meta-analyses of proportions were performed separately for maxillary and mandibular arches using binomial modeling on logit scale. Correlation analyses and univariate linear regression were conducted to assess the relationship between planned expansion and achieved predictability, globally and by arch and tooth group. Risk of bias was evaluated with ROBINS-I and publication bias by funnel plot and Egger\u2019s and Begg\u2019s tests. Certainty of evidence was assessed with GRADE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nine studies were included in the systematic review and eight in the meta-analysis. Pooled predictability of expansion in the maxilla was 65%, with the lowest at permanent first molars (58%) and the highest at deciduous canines (70%). Expansion in the mandible showed higher predictability (71%), peaking at deciduous canines (75%). Correlation and regression analyses found no significant association between amount of planned expansion and achieved predictability in any subgroup. No evidence of publication bias was found, and findings remained robust on sensitivity analysis. GRADE certainty was low (maxilla) and moderate (mandible).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Invisalign First demonstrates modest to moderate predictability for dental arch expansion in mixed dentition, particularly in the mandibular arch and anterior teeth, though limitations persist in the posterior maxilla.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2319\/072425-617.1","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T01:08:06Z","timestamp":1773623286000},"page":"469-481","source":"Crossref","is-referenced-by-count":0,"title":["Predictability of clear aligners in achieving planned dental arch expansion during mixed dentition: a systematic review and meta-analysis"],"prefix":"10.2319","volume":"96","author":[{"given":"Marco","family":"Serafin","sequence":"first","affiliation":[{"name":"Postdoc Fellow, School of Orthodontics, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Boccalari","sequence":"additional","affiliation":[{"name":"PhD Student in Clinical Research, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Caprioglio","sequence":"additional","affiliation":[{"name":"Full Professor and Chairman, School of Orthodontics, Department of Biomedical, Surgical and Dental Sciences, University of Milan; and Fondazione IRCCS Ca\u0300 Granda, Ospedale Maggiore Policlinico, Milan, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"key":"i1945-7103-96-4-469-b01","series-title":"Am J Orthod Dentofacial Orthop","first-page":"567","article-title":"Maxillary transverse deficiency","volume":"117","author":"McNamara","year":"2000","unstructured":"McNamara JA. Maxillary transverse deficiency. Am J Orthod Dentofacial Orthop. 2000;117:567\u2013570."},{"key":"i1945-7103-96-4-469-b02","series-title":"Prog Orthod","first-page":"1","article-title":"Comparison of rapid versus slow maxillary expansion on patient-reported outcome measures in growing patients: a systematic review and meta-analysis","volume":"23","author":"Rutili","year":"2022","unstructured":"Rutili V,\nNieri M,\nFranceschi D,\nPierleoni F,\nGiuntini V,\nFranchi L. Comparison of rapid versus slow maxillary expansion on patient-reported outcome measures in growing patients: a systematic review and meta-analysis. Prog Orthod. 2022;23:1\u201316."},{"key":"i1945-7103-96-4-469-b03","series-title":"Am J Orthod Dentofacial Orthop","first-page":"288","article-title":"Stability of transverse expansion in the mandibular arch","volume":"124","author":"Housley","year":"2003","unstructured":"Housley JA,\nNanda RS,\nCurrier GF,\nMcCune DE. Stability of transverse expansion in the mandibular arch. Am J Orthod Dentofacial Orthop. 2003;124:288\u2013293."},{"key":"i1945-7103-96-4-469-b04","series-title":"Semin Orthod","first-page":"3","article-title":"Design of the Invisalign system performance","volume":"23","author":"Morton","year":"2017","unstructured":"Morton J,\nDerakhshan M,\nKaza S,\nLi C. Design of the Invisalign system performance. Semin Orthod. 2017;23:3\u201311."},{"key":"i1945-7103-96-4-469-b05","series-title":"Children","first-page":"385","article-title":"Clear aligners in the growing patient: a systematic review","volume":"11","author":"Inchingolo","year":"2024","unstructured":"Inchingolo AD,\nDipalma G,\nFerrara I, et al. Clear aligners in the growing patient: a systematic review. Children. 2024;11:385."},{"key":"i1945-7103-96-4-469-b06","series-title":"Appl Sci","first-page":"7233","article-title":"Efficacy of maxillary expansion with clear aligner in the mixed dentition: a systematic review","volume":"15","author":"Levrini","year":"2025","unstructured":"Levrini L,\nZecca PA,\nBorgese M, et al. Efficacy of maxillary expansion with clear aligner in the mixed dentition: a systematic review. Appl Sci. 2025;15:7233."},{"key":"i1945-7103-96-4-469-b07","series-title":"BMC Oral Health","first-page":"1","article-title":"Clinical outcomes of arch expansion with Invisalign: a systematic review","volume":"23","author":"Ma","year":"2023","unstructured":"Ma S,\nWang Y. Clinical outcomes of arch expansion with Invisalign: a systematic review. BMC Oral Health. 2023;23:1\u201317."},{"key":"i1945-7103-96-4-469-b08","series-title":"Int Orthod","first-page":"100750","article-title":"Is maxillary arch expansion with Invisalign\u00ae efficient and predictable? A systematic review","volume":"21","author":"Bouchant","year":"2023","unstructured":"Bouchant M,\nSaade A,\nEl Helou M. Is maxillary arch expansion with Invisalign\u00ae efficient and predictable? A systematic review. Int Orthod. 2023;21:100750."},{"key":"i1945-7103-96-4-469-b09","series-title":"Syst Rev","first-page":"1","article-title":"An evaluation of the Invisalign\u00ae Aligner Technique and consideration of the force system: a systematic review","volume":"13","author":"Caruso","year":"2024","unstructured":"Caruso S,\nDe Felice ME,\nValenti C, et al. An evaluation of the Invisalign\u00ae Aligner Technique and consideration of the force system: a systematic review. Syst Rev. 2024;13:1\u201327."},{"key":"i1945-7103-96-4-469-b10","series-title":"BMJ","first-page":"372","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","author":"Page","year":"2021","unstructured":"Page MJ,\nMcKenzie JE,\nBossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372."},{"key":"i1945-7103-96-4-469-b11","series-title":"J Orofac Orthop","first-page":"33","article-title":"Upper arch dimensional changes with clear aligners in the early mixed dentition: a prospective study","volume":"84","author":"Lione","year":"2023","unstructured":"Lione R,\nCretella Lombardo E,\nPaoloni V,\nMeuli S,\nPavoni C,\nCozza P. Upper arch dimensional changes with clear aligners in the early mixed dentition: a prospective study. J Orofac Orthop. 2023;84:33\u201340."},{"key":"i1945-7103-96-4-469-b12","series-title":"Korean J Orthod","first-page":"85","article-title":"Predictability of maxillary dentoalveolar expansion with clear aligners in patients with mixed dentition","volume":"55","author":"Bruni","year":"2025","unstructured":"Bruni A,\nGallo V,\nParrini S, et al. Predictability of maxillary dentoalveolar expansion with clear aligners in patients with mixed dentition. Korean J Orthod. 2025;55:85\u201394."},{"key":"i1945-7103-96-4-469-b13","series-title":"Angle Orthod","first-page":"392","article-title":"Evaluation of maxillary dimensional changes in the mixed dentition: clear aligners vs acrylic expanders","volume":"94","author":"Pamuk\u00e7u","year":"2024","unstructured":"Pamuk\u00e7u H,\n\u00d6zsoy S,\nAksoy PC,\n\u00d6zsoy \u00d6P. Evaluation of maxillary dimensional changes in the mixed dentition: clear aligners vs acrylic expanders. Angle Orthod. 2024;94:392\u2013399."},{"key":"i1945-7103-96-4-469-b14","series-title":"Healthcare","first-page":"1508","article-title":"Efficacy and predictability of maxillary and mandibular dental arch expansion with clear aligners in prepuberal subjects: a digital retrospective analysis","volume":"13","author":"Caruso","year":"2025","unstructured":"Caruso S,\nNota A,\nTonelli C, et al. Efficacy and predictability of maxillary and mandibular dental arch expansion with clear aligners in prepuberal subjects: a digital retrospective analysis. Healthcare. 2025;13:1508."},{"key":"i1945-7103-96-4-469-b15","series-title":"BMC Oral Health","first-page":"694","article-title":"Predictability of expansion movements performed by clear aligners in mixed dentition in both arches: a retrospective study on digital casts","volume":"24","author":"Loberto","year":"2024","unstructured":"Loberto S,\nPavoni C,\nFanelli S,\nLugli L,\nCozza P,\nLione R. Predictability of expansion movements performed by clear aligners in mixed dentition in both arches: a retrospective study on digital casts. BMC Oral Health. 2024;24:694."},{"key":"i1945-7103-96-4-469-b16","series-title":"Angle Orthod","first-page":"496","article-title":"Vertical and transverse treatment effects of Invisalign First system compared to Hyrax maxillary expanders with fixed appliances in mixed dentition patients","volume":"94","author":"Torbaty","year":"2024","unstructured":"Torbaty PM,\nSuh H,\nTai SK,\nBaird M,\nBoyd RL,\nOh H. Vertical and transverse treatment effects of Invisalign First system compared to Hyrax maxillary expanders with fixed appliances in mixed dentition patients. Angle Orthod. 2024;94:496\u2013503."},{"key":"i1945-7103-96-4-469-b17","series-title":"J Clin Pediatr Dent","first-page":"91","article-title":"The predictability of arch expansion with the Invisalign First system in children with mixed dentition: a retrospective study","volume":"48","author":"Kim","year":"2024","unstructured":"Kim CH,\nMoon SJ,\nKang CM,\nSong JS. The predictability of arch expansion with the Invisalign First system in children with mixed dentition: a retrospective study. J Clin Pediatr Dent. 2024;48:91\u2013100."},{"key":"i1945-7103-96-4-469-b18","series-title":"Appl Sci","first-page":"9871","article-title":"Predictability of maxillary expansion with Invisalign\u00ae First: treatment planning vs. outcome","volume":"14","author":"Levrini","year":"2024","unstructured":"Levrini L,\nZecca PA,\nDeppieri A, et al. Predictability of maxillary expansion with Invisalign\u00ae First: treatment planning vs. outcome. Appl Sci. 2024;14:9871."},{"key":"i1945-7103-96-4-469-b19","series-title":"Eur J Paediatr Dent","first-page":"112","article-title":"Efficiency of Invisalign First\u00ae to promote expansion movement in mixed dentition: a retrospective study and systematic review","volume":"24","author":"Gon\u00e7alves","year":"2023","unstructured":"Gon\u00e7alves A,\nAyache S,\nMonteiro F,\nSilva FS,\nPinho T. Efficiency of Invisalign First\u00ae to promote expansion movement in mixed dentition: a retrospective study and systematic review. Eur J Paediatr Dent. 2023;24:112\u2013123."},{"key":"i1945-7103-96-4-469-b20","series-title":"Angle Orthod","first-page":"19","article-title":"The predictability of transverse changes with Invisalign","volume":"87","author":"Houle","year":"2016","unstructured":"Houle JP,\nPiedade L,\nTodescan R,\nPinheiro FHSL. The predictability of transverse changes with Invisalign. Angle Orthod. 2016;87:19\u201324."},{"key":"i1945-7103-96-4-469-b21","series-title":"Prog Orthod","first-page":"37","article-title":"Clinical effectiveness of Invisalign\u00ae orthodontic treatment: a systematic review","volume":"19","author":"Papadimitriou","year":"2018","unstructured":"Papadimitriou A,\nMousoulea S,\nGkantidis N,\nKloukos D. Clinical effectiveness of Invisalign\u00ae orthodontic treatment: a systematic review. Prog Orthod. 2018;19:37."},{"key":"i1945-7103-96-4-469-b22","series-title":"Angle Orthod","first-page":"881","article-title":"Efficacy of clear aligners in controlling orthodontic tooth movement: a systematic review","volume":"85","author":"Rossini","year":"2014","unstructured":"Rossini G,\nParrini S,\nCastroflorio T,\nDeregibus A,\nDebernardi CL. Efficacy of clear aligners in controlling orthodontic tooth movement: a systematic review. Angle Orthod. 2014;85:881\u2013889."},{"key":"i1945-7103-96-4-469-b23","series-title":"Dentistry Review","first-page":"100074","article-title":"Overview of systematic reviews and meta-analyses assessing the predictability and clinical effectiveness of clear aligner therapy","volume":"3","author":"Alwafi","year":"2023","unstructured":"Alwafi A,\nBichu YM,\nAvanessian A,\nAdel SM,\nVaid NR,\nZou B. Overview of systematic reviews and meta-analyses assessing the predictability and clinical effectiveness of clear aligner therapy. Dentistry Review. 2023;3:100074."},{"key":"i1945-7103-96-4-469-b24","series-title":"Clin Oral Investig","first-page":"257","article-title":"Factors affecting expansion predictability of clear aligner treatment","volume":"29","author":"de-la-Rosa-Gay","year":"2025","unstructured":"de-la-Rosa-Gay C,\nValmaseda-Castell\u00f3n E,\nFigueiredo R,\nCamps-Font O. Factors affecting expansion predictability of clear aligner treatment. Clin Oral Investig. 2025;29:257."},{"key":"i1945-7103-96-4-469-b25","series-title":"Korean J Orthod","first-page":"142","article-title":"Clinical expression of programmed maxillary buccal expansion and buccolingual crown inclination with Invisalign EX30 and SmartTrack aligners and the effect of 1-week vs. 2-week aligner change regimes: a retrospective cohort study","volume":"54","author":"O\u2019Connor","year":"2024","unstructured":"O\u2019Connor J,\nWeir T,\nFreer E,\nKerr B. Clinical expression of programmed maxillary buccal expansion and buccolingual crown inclination with Invisalign EX30 and SmartTrack aligners and the effect of 1-week vs. 2-week aligner change regimes: a retrospective cohort study. Korean J Orthod. 2024;54:142\u2013152."},{"key":"i1945-7103-96-4-469-b26","series-title":"Semin Orthod","first-page":"125","article-title":"The predictability of tooth movement with clear aligner systems","volume":"32","author":"Naoum","year":"2026","unstructured":"Naoum DS,\nLee DR. The predictability of tooth movement with clear aligner systems. Semin Orthod. 2026;32:125\u2013130."},{"key":"i1945-7103-96-4-469-b27","series-title":"Prog Orthod","first-page":"28","article-title":"Indications and limits of clear aligner therapy: an international modified Delphi consensus study","volume":"26","author":"D\u2019Ant\u00f2","year":"2025","unstructured":"D\u2019Ant\u00f2 V,\nOliva G,\nNieri M, et al. Indications and limits of clear aligner therapy: an international modified Delphi consensus study. Prog Orthod. 2025;26:28."},{"key":"i1945-7103-96-4-469-b01","series-title":"Am J Orthod Dentofacial Orthop","first-page":"567","article-title":"Maxillary transverse deficiency","volume":"117","author":"McNamara","year":"2000","unstructured":"McNamara JA. Maxillary transverse deficiency. Am J Orthod Dentofacial Orthop. 2000;117:567\u2013570."},{"key":"i1945-7103-96-4-469-b02","series-title":"Prog Orthod","first-page":"1","article-title":"Comparison of rapid versus slow maxillary expansion on patient-reported outcome measures in growing patients: a systematic review and meta-analysis","volume":"23","author":"Rutili","year":"2022","unstructured":"Rutili V,\nNieri M,\nFranceschi D,\nPierleoni F,\nGiuntini V,\nFranchi L. Comparison of rapid versus slow maxillary expansion on patient-reported outcome measures in growing patients: a systematic review and meta-analysis. Prog Orthod. 2022;23:1\u201316."},{"key":"i1945-7103-96-4-469-b03","series-title":"Am J Orthod Dentofacial Orthop","first-page":"288","article-title":"Stability of transverse expansion in the mandibular arch","volume":"124","author":"Housley","year":"2003","unstructured":"Housley JA,\nNanda RS,\nCurrier GF,\nMcCune DE. Stability of transverse expansion in the mandibular arch. Am J Orthod Dentofacial Orthop. 2003;124:288\u2013293."},{"key":"i1945-7103-96-4-469-b04","series-title":"Semin Orthod","first-page":"3","article-title":"Design of the Invisalign system performance","volume":"23","author":"Morton","year":"2017","unstructured":"Morton J,\nDerakhshan M,\nKaza S,\nLi C. Design of the Invisalign system performance. Semin Orthod. 2017;23:3\u201311."},{"key":"i1945-7103-96-4-469-b05","series-title":"Children","first-page":"385","article-title":"Clear aligners in the growing patient: a systematic review","volume":"11","author":"Inchingolo","year":"2024","unstructured":"Inchingolo AD,\nDipalma G,\nFerrara I, et al. Clear aligners in the growing patient: a systematic review. Children. 2024;11:385."},{"key":"i1945-7103-96-4-469-b06","series-title":"Appl Sci","first-page":"7233","article-title":"Efficacy of maxillary expansion with clear aligner in the mixed dentition: a systematic review","volume":"15","author":"Levrini","year":"2025","unstructured":"Levrini L,\nZecca PA,\nBorgese M, et al. Efficacy of maxillary expansion with clear aligner in the mixed dentition: a systematic review. Appl Sci. 2025;15:7233."},{"key":"i1945-7103-96-4-469-b07","series-title":"BMC Oral Health","first-page":"1","article-title":"Clinical outcomes of arch expansion with Invisalign: a systematic review","volume":"23","author":"Ma","year":"2023","unstructured":"Ma S,\nWang Y. Clinical outcomes of arch expansion with Invisalign: a systematic review. BMC Oral Health. 2023;23:1\u201317."},{"key":"i1945-7103-96-4-469-b08","series-title":"Int Orthod","first-page":"100750","article-title":"Is maxillary arch expansion with Invisalign\u00ae efficient and predictable? A systematic review","volume":"21","author":"Bouchant","year":"2023","unstructured":"Bouchant M,\nSaade A,\nEl Helou M. Is maxillary arch expansion with Invisalign\u00ae efficient and predictable? A systematic review. Int Orthod. 2023;21:100750."},{"key":"i1945-7103-96-4-469-b09","series-title":"Syst Rev","first-page":"1","article-title":"An evaluation of the Invisalign\u00ae Aligner Technique and consideration of the force system: a systematic review","volume":"13","author":"Caruso","year":"2024","unstructured":"Caruso S,\nDe Felice ME,\nValenti C, et al. An evaluation of the Invisalign\u00ae Aligner Technique and consideration of the force system: a systematic review. Syst Rev. 2024;13:1\u201327."},{"key":"i1945-7103-96-4-469-b10","series-title":"BMJ","first-page":"372","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","author":"Page","year":"2021","unstructured":"Page MJ,\nMcKenzie JE,\nBossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372."},{"key":"i1945-7103-96-4-469-b11","series-title":"J Orofac Orthop","first-page":"33","article-title":"Upper arch dimensional changes with clear aligners in the early mixed dentition: a prospective study","volume":"84","author":"Lione","year":"2023","unstructured":"Lione R,\nCretella Lombardo E,\nPaoloni V,\nMeuli S,\nPavoni C,\nCozza P. Upper arch dimensional changes with clear aligners in the early mixed dentition: a prospective study. J Orofac Orthop. 2023;84:33\u201340."},{"key":"i1945-7103-96-4-469-b12","series-title":"Korean J Orthod","first-page":"85","article-title":"Predictability of maxillary dentoalveolar expansion with clear aligners in patients with mixed dentition","volume":"55","author":"Bruni","year":"2025","unstructured":"Bruni A,\nGallo V,\nParrini S, et al. Predictability of maxillary dentoalveolar expansion with clear aligners in patients with mixed dentition. Korean J Orthod. 2025;55:85\u201394."},{"key":"i1945-7103-96-4-469-b13","series-title":"Angle Orthod","first-page":"392","article-title":"Evaluation of maxillary dimensional changes in the mixed dentition: clear aligners vs acrylic expanders","volume":"94","author":"Pamuk\u00e7u","year":"2024","unstructured":"Pamuk\u00e7u H,\n\u00d6zsoy S,\nAksoy PC,\n\u00d6zsoy \u00d6P. Evaluation of maxillary dimensional changes in the mixed dentition: clear aligners vs acrylic expanders. Angle Orthod. 2024;94:392\u2013399."},{"key":"i1945-7103-96-4-469-b14","series-title":"Healthcare","first-page":"1508","article-title":"Efficacy and predictability of maxillary and mandibular dental arch expansion with clear aligners in prepuberal subjects: a digital retrospective analysis","volume":"13","author":"Caruso","year":"2025","unstructured":"Caruso S,\nNota A,\nTonelli C, et al. Efficacy and predictability of maxillary and mandibular dental arch expansion with clear aligners in prepuberal subjects: a digital retrospective analysis. Healthcare. 2025;13:1508."},{"key":"i1945-7103-96-4-469-b15","series-title":"BMC Oral Health","first-page":"694","article-title":"Predictability of expansion movements performed by clear aligners in mixed dentition in both arches: a retrospective study on digital casts","volume":"24","author":"Loberto","year":"2024","unstructured":"Loberto S,\nPavoni C,\nFanelli S,\nLugli L,\nCozza P,\nLione R. Predictability of expansion movements performed by clear aligners in mixed dentition in both arches: a retrospective study on digital casts. BMC Oral Health. 2024;24:694."},{"key":"i1945-7103-96-4-469-b16","series-title":"Angle Orthod","first-page":"496","article-title":"Vertical and transverse treatment effects of Invisalign First system compared to Hyrax maxillary expanders with fixed appliances in mixed dentition patients","volume":"94","author":"Torbaty","year":"2024","unstructured":"Torbaty PM,\nSuh H,\nTai SK,\nBaird M,\nBoyd RL,\nOh H. Vertical and transverse treatment effects of Invisalign First system compared to Hyrax maxillary expanders with fixed appliances in mixed dentition patients. Angle Orthod. 2024;94:496\u2013503."},{"key":"i1945-7103-96-4-469-b17","series-title":"J Clin Pediatr Dent","first-page":"91","article-title":"The predictability of arch expansion with the Invisalign First system in children with mixed dentition: a retrospective study","volume":"48","author":"Kim","year":"2024","unstructured":"Kim CH,\nMoon SJ,\nKang CM,\nSong JS. The predictability of arch expansion with the Invisalign First system in children with mixed dentition: a retrospective study. J Clin Pediatr Dent. 2024;48:91\u2013100."},{"key":"i1945-7103-96-4-469-b18","series-title":"Appl Sci","first-page":"9871","article-title":"Predictability of maxillary expansion with Invisalign\u00ae First: treatment planning vs. outcome","volume":"14","author":"Levrini","year":"2024","unstructured":"Levrini L,\nZecca PA,\nDeppieri A, et al. Predictability of maxillary expansion with Invisalign\u00ae First: treatment planning vs. outcome. Appl Sci. 2024;14:9871."},{"key":"i1945-7103-96-4-469-b19","series-title":"Eur J Paediatr Dent","first-page":"112","article-title":"Efficiency of Invisalign First\u00ae to promote expansion movement in mixed dentition: a retrospective study and systematic review","volume":"24","author":"Gon\u00e7alves","year":"2023","unstructured":"Gon\u00e7alves A,\nAyache S,\nMonteiro F,\nSilva FS,\nPinho T. Efficiency of Invisalign First\u00ae to promote expansion movement in mixed dentition: a retrospective study and systematic review. Eur J Paediatr Dent. 2023;24:112\u2013123."},{"key":"i1945-7103-96-4-469-b20","series-title":"Angle Orthod","first-page":"19","article-title":"The predictability of transverse changes with Invisalign","volume":"87","author":"Houle","year":"2016","unstructured":"Houle JP,\nPiedade L,\nTodescan R,\nPinheiro FHSL. The predictability of transverse changes with Invisalign. Angle Orthod. 2016;87:19\u201324."},{"key":"i1945-7103-96-4-469-b21","series-title":"Prog Orthod","first-page":"37","article-title":"Clinical effectiveness of Invisalign\u00ae orthodontic treatment: a systematic review","volume":"19","author":"Papadimitriou","year":"2018","unstructured":"Papadimitriou A,\nMousoulea S,\nGkantidis N,\nKloukos D. Clinical effectiveness of Invisalign\u00ae orthodontic treatment: a systematic review. Prog Orthod. 2018;19:37."},{"key":"i1945-7103-96-4-469-b22","series-title":"Angle Orthod","first-page":"881","article-title":"Efficacy of clear aligners in controlling orthodontic tooth movement: a systematic review","volume":"85","author":"Rossini","year":"2014","unstructured":"Rossini G,\nParrini S,\nCastroflorio T,\nDeregibus A,\nDebernardi CL. Efficacy of clear aligners in controlling orthodontic tooth movement: a systematic review. Angle Orthod. 2014;85:881\u2013889."},{"key":"i1945-7103-96-4-469-b23","series-title":"Dentistry Review","first-page":"100074","article-title":"Overview of systematic reviews and meta-analyses assessing the predictability and clinical effectiveness of clear aligner therapy","volume":"3","author":"Alwafi","year":"2023","unstructured":"Alwafi A,\nBichu YM,\nAvanessian A,\nAdel SM,\nVaid NR,\nZou B. Overview of systematic reviews and meta-analyses assessing the predictability and clinical effectiveness of clear aligner therapy. Dentistry Review. 2023;3:100074."},{"key":"i1945-7103-96-4-469-b24","series-title":"Clin Oral Investig","first-page":"257","article-title":"Factors affecting expansion predictability of clear aligner treatment","volume":"29","author":"de-la-Rosa-Gay","year":"2025","unstructured":"de-la-Rosa-Gay C,\nValmaseda-Castell\u00f3n E,\nFigueiredo R,\nCamps-Font O. Factors affecting expansion predictability of clear aligner treatment. Clin Oral Investig. 2025;29:257."},{"key":"i1945-7103-96-4-469-b25","series-title":"Korean J Orthod","first-page":"142","article-title":"Clinical expression of programmed maxillary buccal expansion and buccolingual crown inclination with Invisalign EX30 and SmartTrack aligners and the effect of 1-week vs. 2-week aligner change regimes: a retrospective cohort study","volume":"54","author":"O\u2019Connor","year":"2024","unstructured":"O\u2019Connor J,\nWeir T,\nFreer E,\nKerr B. 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