{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T16:13:31Z","timestamp":1758125611980,"version":"3.40.5"},"reference-count":45,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:sec>\n          <jats:title>Objective:<\/jats:title>\n          <jats:p>To determine the effect of Ankaferd Blood Stopper (ABS) on the shear bond strength (SBS) of orthodontic attachments.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Materials and Methods:<\/jats:title>\n          <jats:p>The study material consisted of 60 freshly extracted bovine permanent mandibular incisor teeth. All teeth were cleaned and randomly divided into three groups of 20 specimens and etched with 37% phosphoric acid for 15 seconds, washed, and air-dried. Teeth in groups 1 and 2 were contaminated with ABS and blood, respectively. Teeth in group 3 were only air-dried. Roth Generous maxillary central incisor brackets were bonded with Transbond XT to all teeth. SBS was applied using a universal test machine. The one-way analysis of variance (ANOVA) test was used to determine significant differences in SBS between the three groups, and Tukey honestly significant post hoc test was used to compare subgroups.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Results:<\/jats:title>\n          <jats:p>The mean bond strengths and standard deviations of groups 1, 2, and 3 were 9.58 \u00b1 0.95, 4.04 \u00b1 0.69, and 19.56 \u00b1 1.84 MPa, respectively.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Conclusions:<\/jats:title>\n          <jats:p>Specimens contaminated with blood showed a statistically significant lower in vitro SBS than those contaminated with ABS. ABS may be used clinically for obtaining a blood-free tooth surface during application of the brackets on surgically exposed, impacted teeth.<\/jats:p>\n        <\/jats:sec>","DOI":"10.2319\/080809-448.1","type":"journal-article","created":{"date-parts":[[2010,1,5]],"date-time":"2010-01-05T15:19:40Z","timestamp":1262704780000},"page":"570-574","source":"Crossref","is-referenced-by-count":12,"title":["Plant Extract Ankaferd Blood Stopper Effect on Bond Strength"],"prefix":"10.2319","volume":"80","author":[{"given":"Goksu","family":"Trakyali","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Orthodontics, Faculty of Dentistry, Yeditepe University, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Oguz","family":"Oztoprak","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Orthodontics, Faculty of Dentistry, Yeditepe University, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1164","reference":[{"key":"i0003-3219-80-3-570-b01","series-title":"J Am Dent Assoc","first-page":"497","article-title":"Surgical management of ankylosed impacted maxillary canines.","volume":"102","author":"Shaw, B.","year":"1982","unstructured":"Shaw, B., S. S.Schneider, and J.Zeyer. Surgical management of ankylosed impacted maxillary canines.J Am Dent Assoc1982. 102:497\u2013500."},{"key":"i0003-3219-80-3-570-b02","series-title":"Am J Orthod Dentofacial Orthop","first-page":"149","article-title":"Transalveolar transplantation of maxillary canines.","volume":"90","author":"Sayne, S.","year":"1986","unstructured":"Sayne, S., B.Lennartsson, and B.Thilander. 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Effect of blood and saliva contamination on shear bond strength of brackets bonded with 4 adhesives.Am J Orthod Dentofacial Orthop2007. 131:238\u2013242."},{"key":"i0003-3219-80-3-570-b17","series-title":"J Int Med Res","first-page":"163","article-title":"Haemostatic actions of the folkloric medicinal plant extract Ankaferd Blood Stopper.","volume":"36","author":"Goker, H.","year":"2008","unstructured":"Goker, H., I. C.Haznedaroglu, S.Ercetin, S.Kirazli, U.Akman, Y.Ozturk, and H. C.Firat. 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Angiogenic and proliferative effects of the cytokine VEGF in Ehrlich ascites tumor cells is inhibited by Glycyrrhiza glabra.Int Immunopharmacol2006. 6:494\u2013498."},{"key":"i0003-3219-80-3-570-b22","series-title":"FEMS Microbiol Lett","first-page":"91","article-title":"Enhancement of in vitro growth and resistance to gray mould of Vitis vinifera co-cultured with plant growth-promoting rhizobacteria.","volume":"186","author":"Barka, E. A.","year":"2000","unstructured":"Barka, E. A., A.Belarbi, C.Hachet, J.Nowak, and J. C.Audran. 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Effect of water and saliva contamination on shear bond strength of brackets bonded with conventional, hydrophilic, and self-etching primers.Am J Orthod Dentofacial Orthop2003. 123:633\u2013640."},{"key":"i0003-3219-80-3-570-b26","series-title":"Am J Orthod Dentofacial Orthop","first-page":"207","article-title":"Effects of blood contamination on the shear bond strengths of conventional and hydrophilic primers.","volume":"126","author":"Cacciafesta, V.","year":"2004","unstructured":"Cacciafesta, V., M. F.Sfondrini, A.Scribante, M.De Angelis, and C.Klersy. Effects of blood contamination on the shear bond strengths of conventional and hydrophilic primers.Am J Orthod Dentofacial Orthop2004. 126:207\u2013212."},{"key":"i0003-3219-80-3-570-b27","series-title":"Am J Orthod Dentofacial Orthop","first-page":"514","article-title":"The use of bovine enamel in bonding studies.","volume":"113","author":"Oesterle, L. J.","year":"1998","unstructured":"Oesterle, L. J., W. C.Shellhart, and G. K.Belanger. The use of bovine enamel in bonding studies.Am J Orthod Dentofacial Orthop1998. 113:514\u2013519."},{"key":"i0003-3219-80-3-570-b28","series-title":"Br Dent J","first-page":"171","article-title":"A review of direct orthodontic bonding.","volume":"2","author":"Reynolds, I. R.","year":"1975","unstructured":"Reynolds, I. R.\n          \n          A review of direct orthodontic bonding.\n          Br Dent J\n          1975. 2:171\u2013178."},{"key":"i0003-3219-80-3-570-b29","series-title":"Orthodontic Materials: Scientific and Clinical Aspects","first-page":"107","article-title":"Enamel etching and bond strength.","author":"Powers, J. M.","year":"2001","unstructured":"Powers, J. M. and M. L.Messersmith. Enamel etching and bond strength.InBrantley, W. A. and T.Eliades. Orthodontic Materials: Scientific and Clinical Aspects. 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Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two stage initiation-promotion protocol and identification of procyanidin B5-3\u2032-gallate as the most effective antioxidant constituent.Carcinogenesis1999. 20:1737\u20131745."},{"key":"i0003-3219-80-3-570-b31","series-title":"Atherosclerosis","first-page":"142","article-title":"Proanthocyanidin-rich extract from grape seeds attenuates the development of aortic atherosclerosis in cholesterol-fed rabbits.","author":"Yamakoshi, J.","year":"1999","unstructured":"Yamakoshi, J., S.Kataoka, T.Koga, and T.Ariga. Proanthocyanidin-rich extract from grape seeds attenuates the development of aortic atherosclerosis in cholesterol-fed rabbits.Atherosclerosis1999. 142\u2013149."},{"key":"i0003-3219-80-3-570-b32","series-title":"Am J Gastroenterol","first-page":"2156","article-title":"Endoscopic application of ankaferd blood stopper as a novel experimental treatment modality for upper gastrointestinal bleeding: a case report.","volume":"103","author":"Kurt, M. D. S.","year":"2008","unstructured":"Kurt, M. D. S., M.Akdogan, N.Sasmaz, S.Aksu, and I. C.Haznedaroglu. Endoscopic application of ankaferd blood stopper as a novel experimental treatment modality for upper gastrointestinal bleeding: a case report.Am J Gastroenterol2008. 103:2156\u20132158."},{"issue":"suppl 2","key":"i0003-3219-80-3-570-b33","series-title":"Endoscopy","first-page":"E262","article-title":"Ankaferd Blood Stopper as an effective adjunctive hemostatic agent for the management of life-threatening arterial bleeding of the digestive tract.","volume":"40","author":"Kurt, M.","year":"2008","unstructured":"Kurt, M., S.Kacar, I. K.Onal, M.Akdogan, and I. C.Haznedaroglu. Ankaferd Blood Stopper as an effective adjunctive hemostatic agent for the management of life-threatening arterial bleeding of the digestive tract.Endoscopy2008. 40 (suppl 2):E262."},{"key":"i0003-3219-80-3-570-b34","series-title":"Med Princ Pract","first-page":"165","article-title":"Hemostatic efficacy of Ankaferd Blood Stopper in a swine bleeding model.","volume":"18","author":"Bilgili, H.","year":"2009","unstructured":"Bilgili, H., A.Kosar, M.Kurt, et al. Hemostatic efficacy of Ankaferd Blood Stopper in a swine bleeding model.Med Princ Pract2009. 18:165\u2013169."},{"key":"i0003-3219-80-3-570-b35","series-title":"J Urol","first-page":"2349","article-title":"Hemostatic role of a folkloric medicinal plant extract in a rat partial nephrectomy model: controlled experimental trial.","volume":"181","author":"Huri, E.","year":"2009","unstructured":"Huri, E., T.Akgul, A.Ayyildiz, H.Ustun, and C.Germiyanoglu. Hemostatic role of a folkloric medicinal plant extract in a rat partial nephrectomy model: controlled experimental trial.J Urol2009. 181:2349\u20132354."},{"key":"i0003-3219-80-3-570-b36","series-title":"Clin Appl Thromb Hemost","first-page":"270","article-title":"In vivo hemostatic effect of the medicinal plant extract Ankaferd Blood Stopper in rats pretreated with warfarin.","volume":"15","author":"Cipil, H.","year":"2009","unstructured":"Cipil, H., A.Kosar, A.Kaya, et al. In vivo hemostatic effect of the medicinal plant extract Ankaferd Blood Stopper in rats pretreated with warfarin.Clin Appl Thromb Hemost2009. 15:270\u2013276."},{"key":"i0003-3219-80-3-570-b37","series-title":"Blood Coagul Fibrinolysis","first-page":"185","article-title":"The efficacy of Ankaferd Blood Stopper in antithrombotic drug-induced primary and secondary hemostatic abnormalities of a rat-bleeding model.","volume":"20","author":"Kosar, A.","year":"2009","unstructured":"Kosar, A., H. S.Cipil, A.Kaya, et al. The efficacy of Ankaferd Blood Stopper in antithrombotic drug-induced primary and secondary hemostatic abnormalities of a rat-bleeding model.Blood Coagul Fibrinolysis2009. 20:185\u2013190."},{"key":"i0003-3219-80-3-570-b38","series-title":"Clin Appl Thromb Hemost","article-title":"Oral systemic adminstration of Ankaferd Blood Stopper has no short-term toxicity in an in vivo rabbit experimental model.","author":"Bilgili, H.","year":"2009 Jul 14","unstructured":"Bilgili, H., O.Captug, A.Kosar, et al. Oral systemic adminstration of Ankaferd Blood Stopper has no short-term toxicity in an in vivo rabbit experimental model.Clin Appl Thromb Hemost2009 Jul 14. [Epub ahead of print]."},{"key":"i0003-3219-80-3-570-b39","series-title":"Annual Review of Ankaferd 80-09","first-page":"1","author":"Firat, H.","year":"2009","unstructured":"Firat, H., O.Ozdemir, A.Kosar, H.Goker, and I.Haznedaroglu. Annual Review of Ankaferd 80-09. Istanbul, TurkeyNaviga Scientific Publications. 2009. 1\u2013175."},{"key":"i0003-3219-80-3-570-b40","series-title":"Dig Liver Dis","article-title":"Endoscopic topical application of Ankaferd Blood Stopper for neoplastic gastrointestinal bleeding: a retrospective analysis.","author":"Kurt, M.","year":"2009 Jun 18","unstructured":"Kurt, M., M.Akdogan, I. K.Onal, et al. Endoscopic topical application of Ankaferd Blood Stopper for neoplastic gastrointestinal bleeding: a retrospective analysis.Dig Liver Dis2009 Jun 18. [Epub ahead of print]."},{"key":"i0003-3219-80-3-570-b41","series-title":"IUBMB Life","first-page":"290","article-title":"Molecular basis of the pleiotropic effect of Ankaferd Blood Stopper.","volume":"61","author":"Haznedaroglu, I. C.","year":"2009","unstructured":"Haznedaroglu, I. C.\n          \n          Molecular basis of the pleiotropic effect of Ankaferd Blood Stopper.\n          IUBMB Life\n          2009. 61:290."},{"key":"i0003-3219-80-3-570-b42","series-title":"Blood","first-page":"4203","article-title":"Functional proteomics of Ankaferd Blood Stopper.","volume":"112","author":"Akar, N.","year":"2008","unstructured":"Akar, N., D. O.Demiralp, I. C.Haznedaroglu, and H.Goker. Functional proteomics of Ankaferd Blood Stopper.Blood2008. 112:4203."},{"key":"i0003-3219-80-3-570-b43","series-title":"J Can Dent Assoc","first-page":"827","article-title":"Bleeding disorders: characterization, dental considerations and management.","volume":"72","author":"Israels, S.","year":"2006","unstructured":"Israels, S., N.Schwertz, R.Boyar, and A.McNicol. Bleeding disorders: characterization, dental considerations and management.J Can Dent Assoc2006. 72:827."},{"key":"i0003-3219-80-3-570-b44","series-title":"Fitoterapia","first-page":"48","article-title":"Antimicrobial activity of plant extract Ankaferd Blood Stopper.","volume":"80","author":"Fisgin, N. T.","year":"2009","unstructured":"Fisgin, N. T., Y. T.Cayci, A. Y.Coban, D.Ozatli, E.Tanyel, B.Durupinar, and N.Tulek. Antimicrobial activity of plant extract Ankaferd Blood Stopper.Fitoterapia2009. 80:48\u201350."},{"key":"i0003-3219-80-3-570-b45","series-title":"Int J Lab Hematol","first-page":"95","article-title":"In vitro anti-bacterial activities of Ankaferd blood stopper.","volume":"30","author":"Akkoc, N.","year":"2008","unstructured":"Akkoc, N., M.Acelik, I. C.Haznedaroglu, H.Goker, S.Aksu, S.Kirazli, and H.Firat. In vitro anti-bacterial activities of Ankaferd blood stopper.Int J Lab Hematol2008. 30:95."}],"container-title":["The Angle Orthodontist"],"original-title":[],"link":[{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/80\/3\/article-p570.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/80\/3\/article-p570.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/80\/3\/article-p570.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:51:19Z","timestamp":1747356679000},"score":1,"resource":{"primary":{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/80\/3\/article-p570.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":45,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.2319\/080809-448.1","relation":{},"ISSN":["0003-3219","1945-7103"],"issn-type":[{"type":"print","value":"0003-3219"},{"type":"electronic","value":"1945-7103"}],"subject":[],"published":{"date-parts":[[2010,5]]}}}