{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:12:09Z","timestamp":1787677929319,"version":"build-2784847793"},"reference-count":0,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,16]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the impact of presurgical infant orthopedics (PSIO) on nasolabial appearance among three PSIO methods (modified Grayson\u2019s technique, DynaCleft nasal elevator, OrthoAligner NAM with DynaCleft nasal elevator) and no-PSIO in children with unilateral cleft lip and palate (UCLP) at 4 years\u2019 follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This study took place in an academic and a peripheral center at which patients with UCLP were treated and followed. A total of 48 patients with UCLP were divided into four groups of 12 patients each. Group 1 underwent PSIO using modified Grayson\u2019s technique. Group 2 received PSIO incorporating DynaCleft nasal elevator. Group 3 treatment involved OrthoAligner NAM in combination with DynaCleft nasal elevator, whereas Group 4 did not receive any form of PSIO. Asher-McDade Aesthetic Index (AMAI) and Cleft Aesthetic Rating Scale (CARS) were used to assess nasolabial appearance 4 years post-lip surgery (mean age: 4.3 years \u00b1 6 months) on standardized photographs of the nasolabial region. Kruskal-Wallis test was used to assess nasolabial appearance scores among treatment groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nasolabial appearance showed no significant differences between PSIO and no-PSIO groups across facial esthetic indices regarding nasal form (\n                      <jats:italic>P<\/jats:italic>\n                      = .819), deviation of the nose (\n                      <jats:italic>P<\/jats:italic>\n                      = .403), shape of the vermillion border (\n                      <jats:italic>P<\/jats:italic>\n                      = .801), nasal profile including upper lip (\n                      <jats:italic>P<\/jats:italic>\n                      = .726), nose (\n                      <jats:italic>P<\/jats:italic>\n                      = .973), and lips (\n                      <jats:italic>P<\/jats:italic>\n                      = .72).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with UCLP, there was no significant difference in nasolabial appearance 4 years after lip repair when comparing three different PSIO modalities to no-PSIO group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2319\/082825-729.1","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T01:08:06Z","timestamp":1773623286000},"source":"Crossref","is-referenced-by-count":3,"title":["Impact of three types of presurgical infant orthopedics on nasolabial appearance in unilateral cleft lip and palate: a 4-year follow-up study"],"prefix":"10.2319","author":[{"given":"Puneet","family":"Batra","sequence":"first","affiliation":[{"name":"Dean, Professor and Head, Department of Orthodontics and Dentofacial Orthopedics, Manav Rachna Dental College, Manav Rachna International Institute of Research and Studies, Faridabad, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Kubavat","sequence":"additional","affiliation":[{"name":"Professor and Head, Department of Orthodontics and Dentofacial Orthopedics, Narsinhbhai Patel Dental College, Sankalchand Patel University, Visnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Marie","family":"Kuijpers-Jagtman","sequence":"additional","affiliation":[{"name":"Professor, Department of Orthodontics, University Medical Centre Groningen (UMCG), Groningen, The Netherlands"},{"name":"Professor, Department of Orthodontics and Dentofacial Orthopedics, School of Dental Medicine\/Medical Faculty, University of Bern, Bern, Switzerland"},{"name":"Professor, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno Frazao","family":"Gribel","sequence":"additional","affiliation":[{"name":"Private Practitioner, Compass 3D: Inteligencia e Tecnologia para dentistas, Funcionarios, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhruv","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Orthodontics and Dentofacial Orthopedics, Manav Rachna Dental College, Manav Rachna International Institute of Research and Studies, Faridabad, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","container-title":["The Angle Orthodontist"],"original-title":[],"link":[{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/aop\/article-10.2319-082825-729.1\/article-10.2319-082825-729.1.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/aop\/article-10.2319-082825-729.1\/article-10.2319-082825-729.1.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/aop\/article-10.2319-082825-729.1\/article-10.2319-082825-729.1.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T02:41:05Z","timestamp":1774406465000},"score":1,"resource":{"primary":{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/aop\/article-10.2319-082825-729.1\/article-10.2319-082825-729.1.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,16]]},"references-count":0,"URL":"https:\/\/doi.org\/10.2319\/082825-729.1","relation":{},"ISSN":["1945-7103","0003-3219"],"issn-type":[{"value":"1945-7103","type":"electronic"},{"value":"0003-3219","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,16]]}}}