{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T16:39:09Z","timestamp":1781109549951,"version":"3.54.1"},"reference-count":74,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec id=\"st1\">\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To identify changes in orthodontic management strategies in patients with hypodontia seen in 2000, 2010, and 2017\/2018 (during a 1-year period).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>An assessment of the panoramic radiographs of 3701 patients from a Western Australian private practice identified 276 individuals demonstrating hypodontia. The location of missing teeth, age, sex, type of malocclusion, and the management strategies (space closure or opening) for each patient were noted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Most hypodontia involved agenesis of three or fewer teeth (90%). Maxillary lateral incisors and mandibular second premolars were the most commonly missing teeth. Female preponderance was noted. When considering treatment, the odds ratio for orthodontic space opening and prosthetic replacement in 2000 was 3.266 (\n                      <jats:italic>P<\/jats:italic>\n                      value = 7e-04; 95% confidence interval [CI], 1.464\u20134.633) compared with patients seen in 2010 and 1.632 (\n                      <jats:italic>P<\/jats:italic>\n                      value = 7e-04; 95% CI, 0.811\u20132.434) compared with patients in 2017\/2018. For patients demonstrating bilateral absence of maxillary lateral incisors, the odds ratio for orthodontic space opening was 3.185 (\n                      <jats:italic>P<\/jats:italic>\n                      value = 0.0215; 95% CI, 1.182\u20139.243) compared with counterparts with unilateral agenesis. None of the factors investigated were significantly associated with the types of treatment planned\/provided for the patients with missing mandibular second premolars.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st4\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Maxillary lateral incisors and mandibular second premolars were the most commonly missing teeth. A trend away from space opening and prosthetic replacement toward orthodontic space closure was observed from 2000 to 2017\/2018. This may reflect a change in attitude toward prosthetic replacement options and\/or greater optimism with biomechanical strategies since the implementation of temporary anchorage devices to assist in space closure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2319\/092320-809.1","type":"journal-article","created":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T14:20:08Z","timestamp":1614781208000},"page":"477-483","source":"Crossref","is-referenced-by-count":25,"title":["Trends in orthodontic management strategies for patients with congenitally missing lateral incisors and premolars"],"prefix":"10.2319","volume":"91","author":[{"given":"Steven","family":"Naoum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zjana","family":"Allan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chee Keong","family":"Yeap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Mike","family":"Razza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berwin","family":"Turlach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mithran S.","family":"Goonewardene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"issue":"(4)","key":"i0003-3219-91-4-477-b01","series-title":"Quintessence Int","first-page":"263","article-title":"Hypodontia\u2014a retrospective review of prevalence and etiology. 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