{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:33:58Z","timestamp":1780482838227,"version":"3.54.1"},"reference-count":24,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,11]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective:<\/jats:title>\n To analyze the effect of low-level laser on bone remodeling during induced tooth movement in rats.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n A diode laser (808\u00a0nm, 100\u00a0mW, 54\u00a0J on an area of 0.0028\u00a0cm2<\/jats:sup>) was used. The application was continuous, punctual, and with contact. Forty-two 70-day-old Wistar rats had the maxillary left first molar moved using a force level of 25\u00a0g. In two experimental subgroups the movement was performed over 7\u00a0days and in three subgroups the movement occurred over 14\u00a0days. In the 7-day movement subgroups, one subgroup received laser irradiation on day 1 only; the other subgroup received laser irradiation on days 1, 3, and 5. In the 14-day movement subgroups, one subgroup received laser irradiation on day 1 only; the second on days 1, 3, and 5; and the third on days 1, 3, 5, 7, 9, 11, and 13. The control group was also divided into two subgroups, and movement occurred over two different periods of treatment (7\u00a0days and 14\u00a0days) without laser application; these were used as controls for the respective experimental subgroups. Inter-subgroup comparison was performed with Kruskal-Wallis, followed by Mann-Whitney and analysis of variance, followed by Tukey tests within the 7- and 14-day subgroups.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The subgroup with three laser applications showed significantly greater osteoclastic activity and bone resorption than the other subgroups in the 7-day movement subgroups.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Low-level laser application significantly increased the osteoclastic but not the osteoblastic activity during the initial phases of tooth movement. In addition, the osteoclastic activity was dose-dependent.<\/jats:p>\n <\/jats:sec>","DOI":"10.2319\/100812-789.1","type":"journal-article","created":{"date-parts":[[2013,5,14]],"date-time":"2013-05-14T15:22:30Z","timestamp":1368544950000},"page":"1015-1021","source":"Crossref","is-referenced-by-count":15,"title":["Influence of low-level laser on bone remodeling during induced tooth movement in rats"],"prefix":"10.2319","volume":"83","author":[{"given":"Eliziane","family":"Cossetin","sequence":"first","affiliation":[{"name":"Graduate student, Department of Orthodontics, Bauru Dental School, University of S\u00e3o Paulo, Bauru, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme","family":"Janson","sequence":"additional","affiliation":[{"name":"Professor, Department of Orthodontics, Bauru Dental School, University of S\u00e3o Paulo, Bauru, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Goretti F.","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Professor, College of Medicine, Potiguar University, Natal, Rio Grande do Norte, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rejane A.","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Professor, Department of Operatory Dentistry, Potiguar University, Natal, Rio Grande do Norte, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Fernando Castanha","family":"Henriques","sequence":"additional","affiliation":[{"name":"Professor, Department of Orthodontics, Bauru Dental School, University of S\u00e3o Paulo, Bauru, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Garib","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Orthodontics, Bauru Dental School, University of S\u00e3o Paulo, Bauru, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"key":"i0003-3219-83-6-1015-b01","series-title":"Am J Orthod Dentofacial Orthop","first-page":"662","article-title":"Low-level laser therapy for pain caused by placement of the first orthodontic archwire: a randomized clinical trial","volume":"136","author":"Tortamano\n A,","year":"2009","unstructured":"Tortamano\n A, \n \n Lenzi\n DC, \n \n Haddad\n AC, \n \n Bottino\n MC, \n \n Dominguez\n GC, \n \n Vigorito\n JW. \n \n Low-level laser therapy for pain caused by placement of the first orthodontic archwire: a randomized clinical trial. 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St Louis, Mo: Mosby; 2000: 128\u201339."}],"container-title":["The Angle Orthodontist"],"original-title":[],"link":[{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/83\/6\/article-p1015.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/angle-orthodontist\/article-pdf\/83\/6\/1015\/1396539\/100812-789_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/83\/6\/article-p1015.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/83\/6\/article-p1015.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T01:00:56Z","timestamp":1747357256000},"score":1,"resource":{"primary":{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/83\/6\/article-p1015.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":24,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.2319\/100812-789.1","relation":{},"ISSN":["0003-3219","1945-7103"],"issn-type":[{"value":"0003-3219","type":"print"},{"value":"1945-7103","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11]]}}}