{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:22:22Z","timestamp":1787793742434,"version":"build-2784847793"},"reference-count":22,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:sec>\n          <jats:title>Objective:<\/jats:title>\n          <jats:p>To quantify the amount of tooth movement and orthodontically induced root resorption (OIRR) in ovariectomized rats.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Materials and Methods:<\/jats:title>\n          <jats:p>Five 10-week-old female Wistar rats undergoing ovariectomy (OVX) were investigated as the experimental group, and the other five without ovariectomy served as the control group. Four weeks after ovariectomy, 25-g nickel-titanium closed-coil springs were applied mesially to the maxillary left first molars. Micro\u2013computed tomography was taken at day 0, 1, 3, 7, 14, 21, and 28. At day 28, the molars were extracted. The surface area of root resorption craters, depth, and volume were measured using electron and laser scanning microscopes.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Results:<\/jats:title>\n          <jats:p>Tooth movement gradually increased with time throughout 28\u00a0days. There was a significant difference in the amount of tooth movement between the control group and the OVX group. For OIRR, the OVX group showed wide and shallow root resorption craters scattered on the mesial root. The deep resorption craters were observed on the distal roots distributed in the cervical, middle, and apical thirds of the roots. Statistically significant differences were found between the control and the OVX groups in the depth and the volume of root resorption craters in the distal roots and the total volume of root resorption craters in all three roots.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Conclusion:<\/jats:title>\n          <jats:p>Ovariectomy affected not only tooth movement but also OIRR. Tooth movement in the OVX group was more rapid than the control group. Furthermore, the amount of OIRR in the OVX group was more severe than the control group.<\/jats:p>\n        <\/jats:sec>","DOI":"10.2319\/101710-607.1","type":"journal-article","created":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T01:10:36Z","timestamp":1299028236000},"page":"570-577","source":"Crossref","is-referenced-by-count":43,"title":["Tooth movement and root resorption; The effect of ovariectomy on orthodontic force application in rats"],"prefix":"10.2319","volume":"81","author":[{"given":"Irin","family":"Sirisoontorn","sequence":"first","affiliation":[{"name":"PhD student, Department of Orthodontics and Dentofacial Orthopedics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan"},{"name":"Dentist, Dental section, Panyananthaphikkhu Chonprathan Medical Center Srinakharinwirot University, Nonthaburi, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Hotokezaka","sequence":"additional","affiliation":[{"name":"Senior Assistant Professor, Department of Orthodontics and Dentofacial Orthopedics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"PhD student, Department of Orthodontics and Dentofacial Orthopedics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Gonzales","sequence":"additional","affiliation":[{"name":"Senior Lecturer, Academic Advisor, Department of Orthodontics, The University of Sydney, Sydney Dental Hospital, South Western Sydney Area Health Service, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suwannee","family":"Luppanapornlarp","sequence":"additional","affiliation":[{"name":"Assistant Professor and Chair, Department of Orthodontics, Faculty of Dentistry, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Ali","family":"Darendeliler","sequence":"additional","affiliation":[{"name":"Professor and Chair, Department of Orthodontics, The University of Sydney, Sydney Dental Hospital, South Western Sydney Area Health Service, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Professor and Chair, Department of Orthodontics and Dentofacial Orthopedics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"key":"i0003-3219-81-4-570-b01","series-title":"Orthod Craniofac Res","first-page":"1","article-title":"Bisphosphonates treatment and orthodontic considerations.","volume":"13","author":"Ghoneima, A. A.","year":"2010","unstructured":"Ghoneima, A. A., E. S.Allam, S. L.Zunt, and L. J.Windsor. 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C.\n          \n          Cytokines and estrogen in bone: antiosteoporotic effects.\n          Science\n          1993. 260:626\u2013627."}],"container-title":["The Angle Orthodontist"],"original-title":[],"link":[{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/81\/4\/article-p570.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/81\/4\/article-p570.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/81\/4\/article-p570.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:52:16Z","timestamp":1747356736000},"score":1,"resource":{"primary":{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/81\/4\/article-p570.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":22,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.2319\/101710-607.1","relation":{},"ISSN":["0003-3219","1945-7103"],"issn-type":[{"value":"0003-3219","type":"print"},{"value":"1945-7103","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}