{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:07:52Z","timestamp":1791824872328,"version":"4.3.4"},"reference-count":40,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To compare the root development and the growth rate of the mandibular third molar (M3 inf) in individuals where the M3 inf erupted vs individuals exhibiting M3 inf impaction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Serial standardized intraoral radiographs (Eggen technique) were taken annually of the mandibular third molar region from 132 subjects (71 male and 61 female) from 15 to 20\u00a0years of age. Based on the films, 264 lower third molars were classified into an eruption and an impaction group. Root development was recorded according to a quantitative method described by Haavikko (1970), and the eruption status was analyzed using logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In total, 155 (59%) of the M3 inf erupted, and 109 (41%) were impacted at age 20. In 44 (33%) patients both M3 inf were impacted, in 21 (16%) patients one tooth was erupted and the contralateral tooth impacted, and in 67 (51%) patients both M3 inf were erupted. The more mature a tooth was at age 15, the higher was the probability of eruption (odds ratio: 3.89,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001). The growth rate of the root development stage was statistically significantly associated with the probability of eruption (odds ratio: 10.50,\n                      <jats:italic>P<\/jats:italic>\n                      \u200a=\u200a .041).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Delayed mandibular third molar root development is associated with impaction. Radiographs taken at age 15 may predict the risk of impaction and thereby guide decision making for the orthodontist or the oral and maxillofacial surgeon.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2319\/102911-667.1","type":"journal-article","created":{"date-parts":[[2012,6,16]],"date-time":"2012-06-16T00:14:09Z","timestamp":1339805649000},"page":"3-9","source":"Crossref","is-referenced-by-count":26,"title":["Association between third mandibular molar impaction and degree of root development in adolescents"],"prefix":"10.2319","volume":"83","author":[{"given":"S\u00f8ren R\u00f8dsgaard","family":"Lauesen","sequence":"first","affiliation":[{"name":"Private practitioner, Department of Oral and Maxillofacial Surgery, Faculty of Health and Sciences, Institute of Odontology, University of Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens O.","family":"Andreasen","sequence":"additional","affiliation":[{"name":"Associate and Consultant oral maxiofacial surgeon, Senior research, Resource Center for Rare Oral Diseases, University Hospital of Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas Alexander","family":"Gerds","sequence":"additional","affiliation":[{"name":"Associate Professor, Core Biostatistics, Institute of Public Health, Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren Steno Ahrensburg","family":"Christensen","sequence":"additional","affiliation":[{"name":"Research Assistant, Resource Center for Rare Oral Diseases, University Hospital of Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"Borum","sequence":"additional","affiliation":[{"name":"Head, Municipal Dental Service, Hoeje-Taastrup, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"Hillerup","sequence":"additional","affiliation":[{"name":"Professor, Rigshospitalet and Institute of Odontology, Faculty of Health Sciences, University of Copenhagen, Denmark."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"key":"i0003-3219-83-1-3-b01","series-title":"Am J Orthod","first-page":"237","article-title":"Mandibular growth and third molar impaction","volume":"43","author":"Bj\u00f6rk\n              A ,","year":"1957","unstructured":"Bj\u00f6rk\n              A , \n            \n              Jensen\n              E , \n            \n              Palling\n              M . \n          \n          Mandibular growth and third molar impaction . Am J Orthod . 1957 ;43 :237 \u2013218 ."},{"key":"i0003-3219-83-1-3-b02","series-title":"Am J Orthod Dentofacial Orthop","first-page":"57","article-title":"Tooth size, spacing, and crowding in relation to eruption or impaction of third molars","volume":"94","author":"Forsberg\n              CM .","year":"1988","unstructured":"Forsberg\n              CM . \n          \n          Tooth size, spacing, and crowding in relation to eruption or impaction of third molars . Am J Orthod Dentofacial Orthop . 1988 ;94 :57 \u201362 ."},{"key":"i0003-3219-83-1-3-b03","series-title":"Oral Surg Oral Med Oral Pathol","first-page":"688","article-title":"Prognosis of third molar eruption","volume":"76","author":"Ganss\n              C ,","year":"1993","unstructured":"Ganss\n              C , \n            \n              Hochban\n              W , \n            \n              Kielbassa\n              AM , \n            \n              Umstadt\n              HE . \n          \n          Prognosis of third molar eruption . Oral Surg Oral Med Oral Pathol . 1993 ;76 :688 \u2013693 ."},{"key":"i0003-3219-83-1-3-b04","series-title":"Angle Orthod","first-page":"41","article-title":"Transverse dento-skeletal relationships and third molar impaction","volume":"51","author":"Olive\n              RJ ,","year":"1981","unstructured":"Olive\n              RJ , \n            \n              Basford\n              KE . \n          \n          Transverse dento-skeletal relationships and third molar impaction . Angle Orthod . 1981 ;51 :41 \u201347 ."},{"key":"i0003-3219-83-1-3-b05","series-title":"Br J Oral Maxillofac Surg","first-page":"259","article-title":"Assessing the eruption of lower third molars on the basis of radiographic features","volume":"29","author":"Venta\n              I ,","year":"1991","unstructured":"Venta\n              I , \n            \n              Murtomaa\n              H , \n            \n              Turtola\n              L , \n            \n              Meurman\n              J , \n            \n              Ylipaavalniemi\n              P . \n          \n          Assessing the eruption of lower third molars on the basis of radiographic features . Br J Oral Maxillofac Surg . 1991 ;29 :259 \u2013262 ."},{"key":"i0003-3219-83-1-3-b06","series-title":"Angle Orthod","first-page":"155","article-title":"Lower third molar space","volume":"57","author":"Richardson\n              ME .","year":"1987","unstructured":"Richardson\n              ME . \n          \n          Lower third molar space . Angle Orthod . 1987 ;57 :155 \u2013161 ."},{"key":"i0003-3219-83-1-3-b07","series-title":"Am J Orthod Dentofacial Orthop","first-page":"47","article-title":"Prediction of mandibular third-molar impaction in adolescent orthodontic patients","volume":"130","author":"Behbehani\n              F ,","year":"2006","unstructured":"Behbehani\n              F , \n            \n              Artun\n              J , \n            \n              Thalib\n              L . \n          \n          Prediction of mandibular third-molar impaction in adolescent orthodontic patients . Am J Orthod Dentofacial Orthop . 2006 ;130 :47 \u201355 ."},{"key":"i0003-3219-83-1-3-b08","series-title":"Angle Orthod","first-page":"226","article-title":"The early developmental position of the lower third molar relative to certain jaw dimensions","volume":"40","author":"Richardson\n              ME .","year":"1970","unstructured":"Richardson\n              ME . \n          \n          The early developmental position of the lower third molar relative to certain jaw dimensions . Angle Orthod . 1970 ;40 :226 \u2013230 ."},{"key":"i0003-3219-83-1-3-b09","series-title":"Angle Orthod","first-page":"165","article-title":"The etiology and prediction of mandibular third molar impaction","volume":"47","author":"Richardson\n              ME .","year":"1977","unstructured":"Richardson\n              ME . \n          \n          The etiology and prediction of mandibular third molar impaction . Angle Orthod . 1977 ;47 :165 \u2013172 ."},{"key":"i0003-3219-83-1-3-b10","series-title":"Dtsch Monatschr Zahnheik","first-page":"1264","article-title":"Beitr\u00e4ge zur Frage des Durchbruchs der unteren Weisheitz\u00e4hne","volume":"48","author":"Hammer\n              H .","year":"1930","unstructured":"Hammer\n              H . \n          \n          Beitr\u00e4ge zur Frage des Durchbruchs der unteren Weisheitz\u00e4hne . Dtsch Monatschr Zahnheik . 1930 ;48 :1264 \u20131297 ."},{"key":"i0003-3219-83-1-3-b11","series-title":"Ann Anat","first-page":"339","article-title":"Development of wisdom teeth as a criterion of age determination","volume":"176","author":"K\u00f6hler\n              S ,","year":"1994","unstructured":"K\u00f6hler\n              S , \n            \n              Schmelzle\n              R , \n            \n              Loitz\n              C , \n            \n              P\u00fcschel\n              K . \n          \n          Development of wisdom teeth as a criterion of age determination . Ann Anat . 1994 ;176 :339 \u2013345 ."},{"key":"i0003-3219-83-1-3-b12","series-title":"Eur J Orthod","first-page":"1","article-title":"Third molar impaction\u2014a consequence of late M3 mineralization and early physical maturity","volume":"10","author":"Svendsen\n              H ,","year":"1988","unstructured":"Svendsen\n              H , \n            \n              Bj\u00f6rk\n              A . \n          \n          Third molar impaction\u2014a consequence of late M3 mineralization and early physical maturity . Eur J Orthod . 1988 ;10 :1 \u201312 ."},{"key":"i0003-3219-83-1-3-b13","series-title":"Suom Hammasl\u00e4\u00e4k Toim","first-page":"103","article-title":"The formation and the alveolar and clinical eruption of the permanent teeth. An orthopantomographic study","volume":"66","author":"Haavikko\n              K .","year":"1970","unstructured":"Haavikko\n              K . \n          \n          The formation and the alveolar and clinical eruption of the permanent teeth. An orthopantomographic study . Suom Hammasl\u00e4\u00e4k Toim . 1970 ;66 :103 \u2013170 ."},{"key":"i0003-3219-83-1-3-b14","series-title":"Hum Biol","first-page":"211","article-title":"A new system of dental age assessment","volume":"45","author":"Demirjian\n              A ,","year":"1973","unstructured":"Demirjian\n              A , \n            \n              Goldstein\n              H , \n            \n              Tanner\n              JM . \n          \n          A new system of dental age assessment . Hum Biol . 1973 ;45 :211 \u2013227 ."},{"key":"i0003-3219-83-1-3-b15","series-title":"Ann Anat","first-page":"481","article-title":"The influence of wisdom tooth impaction on root formation","volume":"185","author":"Friedrich\n              RE ,","year":"2003","unstructured":"Friedrich\n              RE , \n            \n              Ulbricht\n              C , \n            \n              Ljuba A\n              Baronesse von Maydell . \n          \n          The influence of wisdom tooth impaction on root formation . Ann Anat . 2003 ;185 :481 \u2013492 ."},{"key":"i0003-3219-83-1-3-b16","series-title":"J Clin Periodontol","first-page":"184","article-title":"Measurements of alveolar bone height at tooth and implant abutments on intraoral radiographs. A comparison of reproducibility of Eggen technique utilized with and without a bite impression","volume":"9","author":"Larheim\n              TA ,","year":"1982","unstructured":"Larheim\n              TA , \n            \n              Eggen\n              S . \n          \n          Measurements of alveolar bone height at tooth and implant abutments on intraoral radiographs. A comparison of reproducibility of Eggen technique utilized with and without a bite impression . J Clin Periodontol . 1982 ;9 :184 \u2013192 ."},{"key":"i0003-3219-83-1-3-b17","series-title":"Biometrika","first-page":"13","article-title":"Longitudinal data analysis using generalized linear models","volume":"73","author":"Liang\n              KY ,","year":"1986","unstructured":"Liang\n              KY , \n            \n              Zeger\n              SL . \n          \n          Longitudinal data analysis using generalized linear models . Biometrika . 1986 ;73 :13 \u201322 ."},{"key":"i0003-3219-83-1-3-b18","series-title":"Swed Dent J","first-page":"161","article-title":"Root development of the lower third molar and its relation to chronological age","volume":"16","author":"Kullman\n              L ,","year":"1992","unstructured":"Kullman\n              L , \n            \n              Johanson\n              G , \n            \n              Akesson\n              L . \n          \n          Root development of the lower third molar and its relation to chronological age . Swed Dent J . 1992 ;16 :161 \u2013167 ."},{"issue":"suppl","key":"i0003-3219-83-1-3-b19","series-title":"Forensic Sci Int","first-page":"S9","article-title":"Third mandibular molar radiological development as an indicator of chronological age in a European population","volume":"146","author":"De Salvia\n              A ,","year":"2004","unstructured":"De Salvia\n              A , \n            \n              Calzetta\n              C , \n            \n              Orrico\n              M , \n            \n              De Leo\n              D . \n          \n          Third mandibular molar radiological development as an indicator of chronological age in a European population . Forensic Sci Int . 2004 ;146 (suppl ):S9 \u2013S12 ."},{"key":"i0003-3219-83-1-3-b20","series-title":"Homo","first-page":"209","article-title":"Studies on the progress of third-molar mineralisation in a Black African population","volume":"57","author":"Olze\n              A ,","year":"2006","unstructured":"Olze\n              A , \n            \n              van Niekerk\n              P , \n            \n              Schmidt\n              S , \n            \n              Wernecke\n              KD , \n            \n              R\u00f6sing\n              FW , \n            \n              Geserick\n              G , \n            \n              Schmeling\n              A . \n          \n          Studies on the progress of third-molar mineralisation in a Black African population . Homo . 2006 ;57 :209 \u2013217 ."},{"key":"i0003-3219-83-1-3-b01","series-title":"Am J Orthod","first-page":"237","article-title":"Mandibular growth and third molar impaction","volume":"43","author":"Bj\u00f6rk\n              A ,","year":"1957","unstructured":"Bj\u00f6rk\n              A , \n            \n              Jensen\n              E , \n            \n              Palling\n              M . \n          \n          Mandibular growth and third molar impaction . Am J Orthod . 1957 ;43 :237 \u2013218 ."},{"key":"i0003-3219-83-1-3-b02","series-title":"Am J Orthod Dentofacial Orthop","first-page":"57","article-title":"Tooth size, spacing, and crowding in relation to eruption or impaction of third molars","volume":"94","author":"Forsberg\n              CM .","year":"1988","unstructured":"Forsberg\n              CM . \n          \n          Tooth size, spacing, and crowding in relation to eruption or impaction of third molars . Am J Orthod Dentofacial Orthop . 1988 ;94 :57 \u201362 ."},{"key":"i0003-3219-83-1-3-b03","series-title":"Oral Surg Oral Med Oral Pathol","first-page":"688","article-title":"Prognosis of third molar eruption","volume":"76","author":"Ganss\n              C ,","year":"1993","unstructured":"Ganss\n              C , \n            \n              Hochban\n              W , \n            \n              Kielbassa\n              AM , \n            \n              Umstadt\n              HE . \n          \n          Prognosis of third molar eruption . Oral Surg Oral Med Oral Pathol . 1993 ;76 :688 \u2013693 ."},{"key":"i0003-3219-83-1-3-b04","series-title":"Angle Orthod","first-page":"41","article-title":"Transverse dento-skeletal relationships and third molar impaction","volume":"51","author":"Olive\n              RJ ,","year":"1981","unstructured":"Olive\n              RJ , \n            \n              Basford\n              KE . \n          \n          Transverse dento-skeletal relationships and third molar impaction . Angle Orthod . 1981 ;51 :41 \u201347 ."},{"key":"i0003-3219-83-1-3-b05","series-title":"Br J Oral Maxillofac Surg","first-page":"259","article-title":"Assessing the eruption of lower third molars on the basis of radiographic features","volume":"29","author":"Venta\n              I ,","year":"1991","unstructured":"Venta\n              I , \n            \n              Murtomaa\n              H , \n            \n              Turtola\n              L , \n            \n              Meurman\n              J , \n            \n              Ylipaavalniemi\n              P . \n          \n          Assessing the eruption of lower third molars on the basis of radiographic features . Br J Oral Maxillofac Surg . 1991 ;29 :259 \u2013262 ."},{"key":"i0003-3219-83-1-3-b06","series-title":"Angle Orthod","first-page":"155","article-title":"Lower third molar space","volume":"57","author":"Richardson\n              ME .","year":"1987","unstructured":"Richardson\n              ME . \n          \n          Lower third molar space . Angle Orthod . 1987 ;57 :155 \u2013161 ."},{"key":"i0003-3219-83-1-3-b07","series-title":"Am J Orthod Dentofacial Orthop","first-page":"47","article-title":"Prediction of mandibular third-molar impaction in adolescent orthodontic patients","volume":"130","author":"Behbehani\n              F ,","year":"2006","unstructured":"Behbehani\n              F , \n            \n              Artun\n              J , \n            \n              Thalib\n              L . \n          \n          Prediction of mandibular third-molar impaction in adolescent orthodontic patients . Am J Orthod Dentofacial Orthop . 2006 ;130 :47 \u201355 ."},{"key":"i0003-3219-83-1-3-b08","series-title":"Angle Orthod","first-page":"226","article-title":"The early developmental position of the lower third molar relative to certain jaw dimensions","volume":"40","author":"Richardson\n              ME .","year":"1970","unstructured":"Richardson\n              ME . \n          \n          The early developmental position of the lower third molar relative to certain jaw dimensions . Angle Orthod . 1970 ;40 :226 \u2013230 ."},{"key":"i0003-3219-83-1-3-b09","series-title":"Angle Orthod","first-page":"165","article-title":"The etiology and prediction of mandibular third molar impaction","volume":"47","author":"Richardson\n              ME .","year":"1977","unstructured":"Richardson\n              ME . \n          \n          The etiology and prediction of mandibular third molar impaction . Angle Orthod . 1977 ;47 :165 \u2013172 ."},{"key":"i0003-3219-83-1-3-b10","series-title":"Dtsch Monatschr Zahnheik","first-page":"1264","article-title":"Beitr\u00e4ge zur Frage des Durchbruchs der unteren Weisheitz\u00e4hne","volume":"48","author":"Hammer\n              H .","year":"1930","unstructured":"Hammer\n              H . \n          \n          Beitr\u00e4ge zur Frage des Durchbruchs der unteren Weisheitz\u00e4hne . Dtsch Monatschr Zahnheik . 1930 ;48 :1264 \u20131297 ."},{"key":"i0003-3219-83-1-3-b11","series-title":"Ann Anat","first-page":"339","article-title":"Development of wisdom teeth as a criterion of age determination","volume":"176","author":"K\u00f6hler\n              S ,","year":"1994","unstructured":"K\u00f6hler\n              S , \n            \n              Schmelzle\n              R , \n            \n              Loitz\n              C , \n            \n              P\u00fcschel\n              K . \n          \n          Development of wisdom teeth as a criterion of age determination . Ann Anat . 1994 ;176 :339 \u2013345 ."},{"key":"i0003-3219-83-1-3-b12","series-title":"Eur J Orthod","first-page":"1","article-title":"Third molar impaction\u2014a consequence of late M3 mineralization and early physical maturity","volume":"10","author":"Svendsen\n              H ,","year":"1988","unstructured":"Svendsen\n              H , \n            \n              Bj\u00f6rk\n              A . \n          \n          Third molar impaction\u2014a consequence of late M3 mineralization and early physical maturity . Eur J Orthod . 1988 ;10 :1 \u201312 ."},{"key":"i0003-3219-83-1-3-b13","series-title":"Suom Hammasl\u00e4\u00e4k Toim","first-page":"103","article-title":"The formation and the alveolar and clinical eruption of the permanent teeth. An orthopantomographic study","volume":"66","author":"Haavikko\n              K .","year":"1970","unstructured":"Haavikko\n              K . \n          \n          The formation and the alveolar and clinical eruption of the permanent teeth. An orthopantomographic study . Suom Hammasl\u00e4\u00e4k Toim . 1970 ;66 :103 \u2013170 ."},{"key":"i0003-3219-83-1-3-b14","series-title":"Hum Biol","first-page":"211","article-title":"A new system of dental age assessment","volume":"45","author":"Demirjian\n              A ,","year":"1973","unstructured":"Demirjian\n              A , \n            \n              Goldstein\n              H , \n            \n              Tanner\n              JM . \n          \n          A new system of dental age assessment . Hum Biol . 1973 ;45 :211 \u2013227 ."},{"key":"i0003-3219-83-1-3-b15","series-title":"Ann Anat","first-page":"481","article-title":"The influence of wisdom tooth impaction on root formation","volume":"185","author":"Friedrich\n              RE ,","year":"2003","unstructured":"Friedrich\n              RE , \n            \n              Ulbricht\n              C , \n            \n              Ljuba A\n              Baronesse von Maydell . \n          \n          The influence of wisdom tooth impaction on root formation . Ann Anat . 2003 ;185 :481 \u2013492 ."},{"key":"i0003-3219-83-1-3-b16","series-title":"J Clin Periodontol","first-page":"184","article-title":"Measurements of alveolar bone height at tooth and implant abutments on intraoral radiographs. A comparison of reproducibility of Eggen technique utilized with and without a bite impression","volume":"9","author":"Larheim\n              TA ,","year":"1982","unstructured":"Larheim\n              TA , \n            \n              Eggen\n              S . \n          \n          Measurements of alveolar bone height at tooth and implant abutments on intraoral radiographs. A comparison of reproducibility of Eggen technique utilized with and without a bite impression . J Clin Periodontol . 1982 ;9 :184 \u2013192 ."},{"key":"i0003-3219-83-1-3-b17","series-title":"Biometrika","first-page":"13","article-title":"Longitudinal data analysis using generalized linear models","volume":"73","author":"Liang\n              KY ,","year":"1986","unstructured":"Liang\n              KY , \n            \n              Zeger\n              SL . \n          \n          Longitudinal data analysis using generalized linear models . Biometrika . 1986 ;73 :13 \u201322 ."},{"key":"i0003-3219-83-1-3-b18","series-title":"Swed Dent J","first-page":"161","article-title":"Root development of the lower third molar and its relation to chronological age","volume":"16","author":"Kullman\n              L ,","year":"1992","unstructured":"Kullman\n              L , \n            \n              Johanson\n              G , \n            \n              Akesson\n              L . \n          \n          Root development of the lower third molar and its relation to chronological age . Swed Dent J . 1992 ;16 :161 \u2013167 ."},{"issue":"suppl","key":"i0003-3219-83-1-3-b19","series-title":"Forensic Sci Int","first-page":"S9","article-title":"Third mandibular molar radiological development as an indicator of chronological age in a European population","volume":"146","author":"De Salvia\n              A ,","year":"2004","unstructured":"De Salvia\n              A , \n            \n              Calzetta\n              C , \n            \n              Orrico\n              M , \n            \n              De Leo\n              D . \n          \n          Third mandibular molar radiological development as an indicator of chronological age in a European population . Forensic Sci Int . 2004 ;146 (suppl ):S9 \u2013S12 ."},{"key":"i0003-3219-83-1-3-b20","series-title":"Homo","first-page":"209","article-title":"Studies on the progress of third-molar mineralisation in a Black African population","volume":"57","author":"Olze\n              A ,","year":"2006","unstructured":"Olze\n              A , \n            \n              van Niekerk\n              P , \n            \n              Schmidt\n              S , \n            \n              Wernecke\n              KD , \n            \n              R\u00f6sing\n              FW , \n            \n              Geserick\n              G , \n            \n              Schmeling\n              A . \n          \n          Studies on the progress of third-molar mineralisation in a Black African population . 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