{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:08:10Z","timestamp":1793052490619,"version":"4.5.0"},"reference-count":26,"publisher":"The Angle Orthodontist (EH Angle Education & Research Foundation)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n To compare vertical and transverse changes in mixed dentition patients treated with the Invisalign First System (IFS) to those treated with a banded hyrax expander with fixed appliances (Hyrax) and control groups, and to assess the efficiency rate of dental arch expansion with IFS.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n The study included 80 mixed dentition patients, with 40 in each group (IFS and Hyrax) and 40 controls from the American Association of Orthodontists Foundation Craniofacial Growth Legacy Collection. Skeletal and dental vertical dimension changes and arch width changes between pretreatment (T1) and posttreatment (T2) were evaluated.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Age at T1, time interval (T1-T2), sex, and Angle class did not significantly differ among the groups. Mandibular plane angle changes showed a similar reduction for the control and IFS groups, with no changes in the Hyrax group. However, the differences among the three groups did not reach statistical significance (\n P<\/jats:italic>\n = .06). The Hyrax group showed significantly greater expansion in maxillary intermolar width compared to the IFS group, 4.4 vs 2.5 mm, respectively. The efficiency of maxillary expansion using IFS ranged from 52.3% to 76.87%.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n During the mixed dentition stage, no significant changes occurred in vertical dimensions among the control, Hyrax, and IFS groups. Although there was a trend suggesting a greater reduction in mandibular plane angle in the IFS group compared to the Hyrax group, this may not be clinically significant given the less than 1\u00b0 difference. IFS can be a viable option for addressing mild arch width deficiencies, with a predictable increase in intermolar width of approximately 2.5 mm.<\/jats:p>\n <\/jats:sec>","DOI":"10.2319\/121023-818.1","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T20:01:34Z","timestamp":1715889694000},"page":"496-503","source":"Crossref","is-referenced-by-count":16,"title":["Vertical and transverse treatment effects of Invisalign First system compared to Hyrax maxillary expanders with fixed appliances in mixed dentition patients"],"prefix":"10.2319","volume":"94","author":[{"given":"Parisa","family":"Moravedje Torbaty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heeyeon","family":"Suh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra Khong","family":"Tai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Baird","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Boyd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heesoo","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1164","reference":[{"key":"i1945-7103-94-5-496-b01","series-title":"Am J Orthod Dentofacial Orthop","first-page":"567","article-title":"Maxillary transverse deficiency","volume":"117","author":"McNamara","year":"2000","unstructured":"McNamara\n JA.\n \n \n Maxillary transverse deficiency. Am J Orthod Dentofacial Orthop. 2000;117:567\u2013570."},{"key":"i1945-7103-94-5-496-b02","series-title":"Contemporary Orthodontics","first-page":"430","author":"Proffit","year":"2019","unstructured":"Proffit\n WR,\n \n \n Fields\n HW,\n \n \n Larson\n BE,\n \n \n Sarver\n DM.\n \n \n \n Contemporary Orthodontics\n . 6th ed. Philadelphia: Elsevier; 2019:430\u2013436."},{"key":"i1945-7103-94-5-496-b03","series-title":"Eur J Paediatr Dent","first-page":"112","article-title":"Efficiency of Invisalign First\u00ae to promote expansion movement in mixed dentition: a retrospective study and systematic review","volume":"24","author":"Gon\u00e7alves","year":"2023","unstructured":"Gon\u00e7alves\n A,\n \n \n Ayache\n S,\n \n \n Monteiro\n F,\n \n \n Silva\n FS,\n \n \n Pinho\n T.\n \n \n Efficiency of Invisalign First\u00ae to promote expansion movement in mixed dentition: a retrospective study and systematic review. Eur J Paediatr Dent. 2023;24:112\u2013123."},{"key":"i1945-7103-94-5-496-b04","series-title":"BMC Oral Health","first-page":"598","article-title":"Treatment effects after maxillary expansion using invisalign first system vs. acrylic splint expander in mixed dentition: a prospective cohort study","volume":"23","author":"Lu","year":"2023","unstructured":"Lu\n L,\n \n \n Zhang\n L,\n \n \n Li\n C,\n \n \n Yi\n F,\n \n \n Lei\n L,\n \n \n Lu\n Y.\n \n \n Treatment effects after maxillary expansion using invisalign first system vs. acrylic splint expander in mixed dentition: a prospective cohort study. BMC Oral Health. 2023;23:598."},{"key":"i1945-7103-94-5-496-b05","series-title":"Life (Basel)","first-page":"1323","article-title":"Evaluation of the upper arch morphological changes after two different protocols of expansion in early mixed dentition: rapid maxillary expansion and Invisalign\u00ae First System","volume":"12","author":"Cretella Lombardo","year":"2022","unstructured":"Cretella Lombardo\n E,\n \n \n Paoloni\n V,\n \n et al.\n Evaluation of the upper arch morphological changes after two different protocols of expansion in early mixed dentition: rapid maxillary expansion and Invisalign\u00ae First System. Life (Basel). 2022;26;12:1323."},{"key":"i1945-7103-94-5-496-b06","series-title":"Angle Orthod","first-page":"524","article-title":"Dimensional changes in the palate associated with Invisalign First System: a pilot study","volume":"93","author":"Wang","year":"2023","unstructured":"Wang\n J,\n \n \n Bukhari\n A,\n \n \n Tai\n SK,\n \n \n Zou\n B.\n \n \n Dimensional changes in the palate associated with Invisalign First System: a pilot study. Angle Orthod. 2023;93:524\u2013530."},{"key":"i1945-7103-94-5-496-b07","series-title":"Am J Orthod Dentofacial Orthop","first-page":"322","article-title":"Biomechanical basis of vertical dimension control during rapid palatal expansion therapy","volume":"106","author":"Majourau","year":"1994","unstructured":"Majourau\n A,\n \n \n Nanda\n R.\n \n \n Biomechanical basis of vertical dimension control during rapid palatal expansion therapy. Am J Orthod Dentofacial Orthop. 1994;106:322\u2013328."},{"key":"i1945-7103-94-5-496-b08","series-title":"Am J Orthod Dentofacial Orthop","first-page":"319","article-title":"Dentoskeletal effects of rapid maxillary expander therapy in early mixed dentition patients with different vertical growing patterns without posterior crossbite: a retrospective study","volume":"163","author":"Rozzi","year":"2023","unstructured":"Rozzi\n M,\n \n \n Alesi\n G,\n \n \n Mucedero\n M,\n \n \n Cozza\n P.\n \n \n Dentoskeletal effects of rapid maxillary expander therapy in early mixed dentition patients with different vertical growing patterns without posterior crossbite: a retrospective study. Am J Orthod Dentofacial Orthop. 2023;163:319\u2013327."},{"issue":"3","key":"i1945-7103-94-5-496-b09","series-title":"Eur J Orthod","first-page":"301","article-title":"Dento-skeletal effects produced by rapid versus slow maxillary expansion using fixed jackscrew expanders: a systematic review and meta-analysis","volume":"43","author":"Rutili","year":"2021","unstructured":"Rutili\n V,\n \n \n Mrakic\n G,\n \n \n Nieri\n M,\n \n et al.\n Dento-skeletal effects produced by rapid versus slow maxillary expansion using fixed jackscrew expanders: a systematic review and meta-analysis. Eur J Orthod. 2021;43(3):301\u2013312."},{"key":"i1945-7103-94-5-496-b10","series-title":"Dental Press J. Orthod","first-page":"62","article-title":"Cephalometric evaluation of vertical and anteroposterior changes associated with the use of bonded rapid maxillary expansion appliance","volume":"15","author":"Rossi","year":"2010","unstructured":"Rossi\n M,\n \n \n Stuani\n M,\n \n \n Silva\n L.\n \n \n Cephalometric evaluation of vertical and anteroposterior changes associated with the use of bonded rapid maxillary expansion appliance. Dental Press J. Orthod. 2010;15:62\u201370."},{"key":"i1945-7103-94-5-496-b11","series-title":"Angle Orthod","first-page":"925","article-title":"Assessment of vertical changes during maxillary expansion using quad-helix or bonded rapid maxillary expander","volume":"86","author":"Conroy-Piskai","year":"2016","unstructured":"Conroy-Piskai\n C,\n \n \n Galang-Boquiren\n MT,\n \n \n Obrez\n A,\n \n et al.\n Assessment of vertical changes during maxillary expansion using quad-helix or bonded rapid maxillary expander. Angle Orthod. 2016;86:925\u2013933."},{"key":"i1945-7103-94-5-496-b12","series-title":"Am J Orthod Dentofacial Orthop","first-page":"774","article-title":"Short-term stability of anterior open bite treatment with clear aligners in adults","volume":"164","author":"Suh","year":"2023","unstructured":"Suh\n H,\n \n \n Garnett\n BS,\n \n \n Mahood\n K,\n \n \n Boyd\n RL,\n \n \n Oh\n H.\n \n \n Short-term stability of anterior open bite treatment with clear aligners in adults. Am J Orthod Dentofacial Orthop. 2023;164:774\u2013782."},{"key":"i1945-7103-94-5-496-b13","series-title":"Am J Orthod Dentofacial Orthop","first-page":"691","article-title":"Management of overbite with the Invisalign appliance","volume":"151","author":"Khosravi","year":"2017","unstructured":"Khosravi\n R,\n \n \n Cohanim\n B,\n \n \n Hujoel\n P,\n \n et al.\n Management of overbite with the Invisalign appliance. Am J Orthod Dentofacial Orthop. 2017;151:691\u2013699."},{"key":"i1945-7103-94-5-496-b01","series-title":"Am J Orthod Dentofacial Orthop","first-page":"567","article-title":"Maxillary transverse deficiency","volume":"117","author":"McNamara","year":"2000","unstructured":"McNamara\n JA.\n \n \n Maxillary transverse deficiency. Am J Orthod Dentofacial Orthop. 2000;117:567\u2013570."},{"key":"i1945-7103-94-5-496-b02","series-title":"Contemporary Orthodontics","first-page":"430","author":"Proffit","year":"2019","unstructured":"Proffit\n WR,\n \n \n Fields\n HW,\n \n \n Larson\n BE,\n \n \n Sarver\n DM.\n \n \n \n Contemporary Orthodontics\n . 6th ed. Philadelphia: Elsevier; 2019:430\u2013436."},{"key":"i1945-7103-94-5-496-b03","series-title":"Eur J Paediatr Dent","first-page":"112","article-title":"Efficiency of Invisalign First\u00ae to promote expansion movement in mixed dentition: a retrospective study and systematic review","volume":"24","author":"Gon\u00e7alves","year":"2023","unstructured":"Gon\u00e7alves\n A,\n \n \n Ayache\n S,\n \n \n Monteiro\n F,\n \n \n Silva\n FS,\n \n \n Pinho\n T.\n \n \n Efficiency of Invisalign First\u00ae to promote expansion movement in mixed dentition: a retrospective study and systematic review. Eur J Paediatr Dent. 2023;24:112\u2013123."},{"key":"i1945-7103-94-5-496-b04","series-title":"BMC Oral Health","first-page":"598","article-title":"Treatment effects after maxillary expansion using invisalign first system vs. acrylic splint expander in mixed dentition: a prospective cohort study","volume":"23","author":"Lu","year":"2023","unstructured":"Lu\n L,\n \n \n Zhang\n L,\n \n \n Li\n C,\n \n \n Yi\n F,\n \n \n Lei\n L,\n \n \n Lu\n Y.\n \n \n Treatment effects after maxillary expansion using invisalign first system vs. acrylic splint expander in mixed dentition: a prospective cohort study. BMC Oral Health. 2023;23:598."},{"key":"i1945-7103-94-5-496-b05","series-title":"Life (Basel)","first-page":"1323","article-title":"Evaluation of the upper arch morphological changes after two different protocols of expansion in early mixed dentition: rapid maxillary expansion and Invisalign\u00ae First System","volume":"12","author":"Cretella Lombardo","year":"2022","unstructured":"Cretella Lombardo\n E,\n \n \n Paoloni\n V,\n \n et al.\n Evaluation of the upper arch morphological changes after two different protocols of expansion in early mixed dentition: rapid maxillary expansion and Invisalign\u00ae First System. Life (Basel). 2022;26;12:1323."},{"key":"i1945-7103-94-5-496-b06","series-title":"Angle Orthod","first-page":"524","article-title":"Dimensional changes in the palate associated with Invisalign First System: a pilot study","volume":"93","author":"Wang","year":"2023","unstructured":"Wang\n J,\n \n \n Bukhari\n A,\n \n \n Tai\n SK,\n \n \n Zou\n B.\n \n \n Dimensional changes in the palate associated with Invisalign First System: a pilot study. Angle Orthod. 2023;93:524\u2013530."},{"key":"i1945-7103-94-5-496-b07","series-title":"Am J Orthod Dentofacial Orthop","first-page":"322","article-title":"Biomechanical basis of vertical dimension control during rapid palatal expansion therapy","volume":"106","author":"Majourau","year":"1994","unstructured":"Majourau\n A,\n \n \n Nanda\n R.\n \n \n Biomechanical basis of vertical dimension control during rapid palatal expansion therapy. Am J Orthod Dentofacial Orthop. 1994;106:322\u2013328."},{"key":"i1945-7103-94-5-496-b08","series-title":"Am J Orthod Dentofacial Orthop","first-page":"319","article-title":"Dentoskeletal effects of rapid maxillary expander therapy in early mixed dentition patients with different vertical growing patterns without posterior crossbite: a retrospective study","volume":"163","author":"Rozzi","year":"2023","unstructured":"Rozzi\n M,\n \n \n Alesi\n G,\n \n \n Mucedero\n M,\n \n \n Cozza\n P.\n \n \n Dentoskeletal effects of rapid maxillary expander therapy in early mixed dentition patients with different vertical growing patterns without posterior crossbite: a retrospective study. Am J Orthod Dentofacial Orthop. 2023;163:319\u2013327."},{"issue":"3","key":"i1945-7103-94-5-496-b09","series-title":"Eur J Orthod","first-page":"301","article-title":"Dento-skeletal effects produced by rapid versus slow maxillary expansion using fixed jackscrew expanders: a systematic review and meta-analysis","volume":"43","author":"Rutili","year":"2021","unstructured":"Rutili\n V,\n \n \n Mrakic\n G,\n \n \n Nieri\n M,\n \n et al.\n Dento-skeletal effects produced by rapid versus slow maxillary expansion using fixed jackscrew expanders: a systematic review and meta-analysis. Eur J Orthod. 2021;43(3):301\u2013312."},{"key":"i1945-7103-94-5-496-b10","series-title":"Dental Press J. Orthod","first-page":"62","article-title":"Cephalometric evaluation of vertical and anteroposterior changes associated with the use of bonded rapid maxillary expansion appliance","volume":"15","author":"Rossi","year":"2010","unstructured":"Rossi\n M,\n \n \n Stuani\n M,\n \n \n Silva\n L.\n \n \n Cephalometric evaluation of vertical and anteroposterior changes associated with the use of bonded rapid maxillary expansion appliance. Dental Press J. Orthod. 2010;15:62\u201370."},{"key":"i1945-7103-94-5-496-b11","series-title":"Angle Orthod","first-page":"925","article-title":"Assessment of vertical changes during maxillary expansion using quad-helix or bonded rapid maxillary expander","volume":"86","author":"Conroy-Piskai","year":"2016","unstructured":"Conroy-Piskai\n C,\n \n \n Galang-Boquiren\n MT,\n \n \n Obrez\n A,\n \n et al.\n Assessment of vertical changes during maxillary expansion using quad-helix or bonded rapid maxillary expander. Angle Orthod. 2016;86:925\u2013933."},{"key":"i1945-7103-94-5-496-b12","series-title":"Am J Orthod Dentofacial Orthop","first-page":"774","article-title":"Short-term stability of anterior open bite treatment with clear aligners in adults","volume":"164","author":"Suh","year":"2023","unstructured":"Suh\n H,\n \n \n Garnett\n BS,\n \n \n Mahood\n K,\n \n \n Boyd\n RL,\n \n \n Oh\n H.\n \n \n Short-term stability of anterior open bite treatment with clear aligners in adults. Am J Orthod Dentofacial Orthop. 2023;164:774\u2013782."},{"key":"i1945-7103-94-5-496-b13","series-title":"Am J Orthod Dentofacial Orthop","first-page":"691","article-title":"Management of overbite with the Invisalign appliance","volume":"151","author":"Khosravi","year":"2017","unstructured":"Khosravi\n R,\n \n \n Cohanim\n B,\n \n \n Hujoel\n P,\n \n et al.\n Management of overbite with the Invisalign appliance. Am J Orthod Dentofacial Orthop. 2017;151:691\u2013699."}],"container-title":["The Angle Orthodontist"],"original-title":[],"link":[{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/94\/5\/article-p496.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/meridian.allenpress.com\/angle-orthodontist\/article-pdf\/94\/5\/496\/3426747\/i1945-7103-94-5-496.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/94\/5\/article-p496.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/downloadpdf\/journals\/angl\/94\/5\/article-p496.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T14:19:43Z","timestamp":1780064383000},"score":1,"resource":{"primary":{"URL":"https:\/\/angle-orthodontist.kglmeridian.com\/view\/journals\/angl\/94\/5\/article-p496.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":26,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.2319\/121023-818.1","relation":{},"ISSN":["1945-7103","0003-3219"],"issn-type":[{"value":"1945-7103","type":"electronic"},{"value":"0003-3219","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]}}}