{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:18:46Z","timestamp":1782602326371,"version":"3.54.5"},"reference-count":30,"publisher":"Japanese Society of Allergology","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,4,29]],"date-time":"2015-04-29T00:00:00Z","timestamp":1430265600000},"content-version":"vor","delay-in-days":483,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergology International"],"published-print":{"date-parts":[[2014]]},"DOI":"10.2332\/allergolint.13-oa-0635","type":"journal-article","created":{"date-parts":[[2014,5,25]],"date-time":"2014-05-25T22:53:43Z","timestamp":1401058423000},"page":"29-35","source":"Crossref","is-referenced-by-count":8,"special_numbering":"S1","title":["Selective Suppression of Th2 Cell-Mediated Lung Eosinophilic Inflammation by Anti-Major Facilitator Super Family Domain Containing 10 Monoclonal Antibody"],"prefix":"10.2332","volume":"63","author":[{"given":"Tomoe","family":"Nishimura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayumi","family":"Saeki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Motoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Kitamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Kaminuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takachika","family":"Hiroi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1154","reference":[{"key":"10.2332\/allergolint.13-OA-0635_bb0005","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1600-065X.2011.01032.x","article-title":"Human asthma phenotypes: from the clinic, to cytokines, and back again","volume":"242","author":"Bhakta","year":"2011","journal-title":"Immunol Rev"},{"key":"10.2332\/allergolint.13-OA-0635_bb0010","doi-asserted-by":"crossref","first-page":"32883","DOI":"10.1074\/jbc.R110.197046","article-title":"Allergic asthma: influence of genetic and environmental factors","volume":"286","author":"Mukherjee","year":"2011","journal-title":"J Biol Chem"},{"key":"10.2332\/allergolint.13-OA-0635_bb0015","doi-asserted-by":"crossref","first-page":"3236","DOI":"10.1182\/blood-2011-11-391532","article-title":"Asthma and coagulation","volume":"119","author":"de Boer","year":"2012","journal-title":"Blood"},{"key":"10.2332\/allergolint.13-OA-0635_bb0020","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1600-065X.2011.01026.x","article-title":"Eosinophils: multifaceted biological properties and roles in health and disease","volume":"242","author":"Kita","year":"2011","journal-title":"Immunol Rev"},{"key":"10.2332\/allergolint.13-OA-0635_bb0025","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1016\/S0140-6736(00)03496-6","article-title":"Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and late asthmatic response","volume":"356","author":"Leckie","year":"2000","journal-title":"Lancet"},{"key":"10.2332\/allergolint.13-OA-0635_bb0030","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1164\/rccm.200208-789OC","article-title":"Eosinophil\u2019s role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway","volume":"167","author":"Flood-Page","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"key":"10.2332\/allergolint.13-OA-0635_bb0035","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1056\/NEJMoa0808991","article-title":"Mepolizumab and exacerbations of refractory eosinophilic asthma","volume":"360","author":"Haldar","year":"2009","journal-title":"N Engl J Med"},{"key":"10.2332\/allergolint.13-OA-0635_bb0040","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1056\/NEJMoa0805435","article-title":"Mepolizumab for prednisone-dependent asthma with sputum eosinophilia","volume":"360","author":"Nair","year":"2009","journal-title":"N Engl J Med"},{"key":"10.2332\/allergolint.13-OA-0635_bb0045","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1111\/j.1398-9995.2011.02638.x","article-title":"Dose-response effects of TPI ASM8 in asthmatics after allergen","volume":"66","author":"Gauvreau","year":"2011","journal-title":"Allergy"},{"key":"10.2332\/allergolint.13-OA-0635_bb0050","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1074\/jbc.270.3.1462","article-title":"Identification and characterization of a functional promoter region in the human eosinophil IL-5 receptor alpha subunit gene","volume":"270","author":"Sun","year":"1995","journal-title":"J Biol Chem"},{"key":"10.2332\/allergolint.13-OA-0635_bb0055","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1002\/eji.200324723","article-title":"The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils","volume":"34","author":"Zhang","year":"2004","journal-title":"Eur J immunol"},{"key":"10.2332\/allergolint.13-OA-0635_bb0060","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1084\/jem.183.6.2437","article-title":"Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils","volume":"183","author":"Ponath","year":"1996","journal-title":"J Exp Med"},{"key":"10.2332\/allergolint.13-OA-0635_bb0065","doi-asserted-by":"crossref","first-page":"5333","DOI":"10.4049\/jimmunol.0801421","article-title":"Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling","volume":"183","author":"Song","year":"2009","journal-title":"J Immunol"},{"key":"10.2332\/allergolint.13-OA-0635_bb0070","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1111\/j.1398-9995.2008.01709.x","article-title":"Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils","volume":"63","author":"Zimmermann","year":"2008","journal-title":"Allergy"},{"key":"10.2332\/allergolint.13-OA-0635_bb0075","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1152\/ajplung.00260.2002","article-title":"Ablation of eosinophils leads to a reduction of allergen-induced pulmonary pathology","volume":"284","author":"Justice","year":"2003","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.2332\/allergolint.13-OA-0635_bb0080","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1097\/01.LAB.0000020417.13757.05","article-title":"CCR3-blocking antibody inhibits allergen-induced eosinophil recruitment in human skin xenografts from allergic patients","volume":"82","author":"S\u00e9n\u00e9chal","year":"2002","journal-title":"Lab Invest"},{"key":"10.2332\/allergolint.13-OA-0635_bb0085","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.jaci.2010.04.004","article-title":"MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function","volume":"125","author":"Kolbeck","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.2332\/allergolint.13-OA-0635_bb0090","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/j.febslet.2007.03.001","article-title":"Identification of the TPO1 gene in yeast, and its human orthologue TETRAN, which cause resistance to NSAIDs","volume":"581","author":"Mima","year":"2007","journal-title":"FEBS Lett"},{"key":"10.2332\/allergolint.13-OA-0635_bb0095","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.bbrc.2008.07.034","article-title":"Expression and function of TETRAN, a new type of membrane transporter","volume":"374","author":"Ushijima","year":"2008","journal-title":"Biochem Biophys Res Commun"},{"key":"10.2332\/allergolint.13-OA-0635_bb0100","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.imlet.2012.07.001","article-title":"Establishment of monoclonal antibodies against a novel eosinophil-specific cell surface molecule, major facilitator super family domain containing 10","volume":"147","author":"Motoi","year":"2012","journal-title":"Immunol Lett"},{"key":"10.2332\/allergolint.13-OA-0635_bb0105","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1165\/ajrcmb.16.4.9115756","article-title":"Successful transfer of late phase eosinophil infiltration in the lung by infusion of helper T cell clones","volume":"16","author":"Kaminuma","year":"1997","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.2332\/allergolint.13-OA-0635_bb0110","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/intimm\/dxm049","article-title":"Selective suppression of Th2-mediated airway eosinophil infiltration by low-molecular weight CCR3 antagonists","volume":"19","author":"Mori","year":"2007","journal-title":"Int Immunol"},{"key":"10.2332\/allergolint.13-OA-0635_bb0115","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1365-2222.2011.03847.x","article-title":"Selective down-regulation of Th2 cell-mediated airway inflammation in mice by pharmacological intervention of CCR4","volume":"42","author":"Kaminuma","year":"2012","journal-title":"Clin Exp Allergy"},{"key":"10.2332\/allergolint.13-OA-0635_bb0120","doi-asserted-by":"crossref","first-page":"4280","DOI":"10.1182\/blood-2006-08-039255","article-title":"Defining the in vivo function of Siglec-F, a CD33- related Siglec expressed on mouse eosinophils","volume":"109","author":"Zhang","year":"2007","journal-title":"Blood"},{"key":"10.2332\/allergolint.13-OA-0635_bb0125","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1056\/NEJM199201303260504","article-title":"Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma","volume":"30","author":"Robinson","year":"1992","journal-title":"N Engl J Med"},{"key":"10.2332\/allergolint.13-OA-0635_bb0130","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1165\/ajrcmb.12.5.7742012","article-title":"Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects","volume":"12","author":"Ying","year":"1995","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.2332\/allergolint.13-OA-0635_bb0135","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1002\/1521-4141(200109)31:9<2669::AID-IMMU2669>3.0.CO;2-Y","article-title":"Dynamics of antigen-specific helper T cells at the initiation of airway eosinophilic inflammation","volume":"31","author":"Kaminuma","year":"2001","journal-title":"Eur J Immunol"},{"key":"10.2332\/allergolint.13-OA-0635_bb0140","doi-asserted-by":"crossref","first-page":"5014","DOI":"10.1182\/blood-2002-10-3058","article-title":"Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis","volume":"101","author":"Nutku","year":"2003","journal-title":"Blood"},{"key":"10.2332\/allergolint.13-OA-0635_bb0145","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.bbrc.2005.08.202","article-title":"Mechanism of Siglec-8-induced human eosinophil apoptosis: role of caspases and mitochondrial injury","volume":"336","author":"Nutku","year":"2005","journal-title":"Biochem Biophys Res Commun"},{"key":"10.2332\/allergolint.13-OA-0635_bb0150","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.jaci.2007.01.023","article-title":"Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies","volume":"119","author":"von Gunten","year":"2007","journal-title":"J Allergy Clin Immunol"}],"container-title":["Allergology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1323893015300812?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1323893015300812?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,10]],"date-time":"2019-08-10T23:52:31Z","timestamp":1565481151000},"score":1,"resource":{"primary":{"URL":"http:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1323893015300812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":30,"alternative-id":["S1323893015300812"],"URL":"https:\/\/doi.org\/10.2332\/allergolint.13-oa-0635","relation":{},"ISSN":["1323-8930"],"issn-type":[{"value":"1323-8930","type":"print"}],"subject":[],"published":{"date-parts":[[2014]]}}}