{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:00:21Z","timestamp":1760101221245,"version":"3.37.3"},"reference-count":62,"publisher":"Nihon University School of Dentistry","issue":"2","funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP17K11775"],"award-info":[{"award-number":["JP17K11775"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Sci","Journal of Oral Science"],"published-print":{"date-parts":[[2020]]},"DOI":"10.2334\/josnusd.19-0408","type":"journal-article","created":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T22:05:23Z","timestamp":1585346723000},"page":"156-159","source":"Crossref","is-referenced-by-count":9,"title":["Evaluation of the association between orofacial pain and dysphagia"],"prefix":"10.2334","volume":"62","author":[{"given":"Takanori","family":"Tsujimura","sequence":"first","affiliation":[{"name":"Division of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Inoue","sequence":"additional","affiliation":[{"name":"Division of Dysphagia Rehabilitation, Niigata University Graduate School of Medical and Dental Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1160","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Miyashita N, Yamauchi Y (2018) Bacterial pneumonia in elderly Japanese populations. Jpn Clin Med 9, 1179670717751433.","DOI":"10.1177\/1179670717751433"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Teramoto S, Fukuchi Y, Sasaki H, Sato K, Sekizawa K, Matsuse T et al. (2008) High incidence of aspiration pneumonia in community- and hospital-acquired pneumonia in hospitalized patients: a multicenter, prospective study in Japan. J Am Geriatr Soc 56, 577-579.","DOI":"10.1111\/j.1532-5415.2008.01597.x"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Marik PE, Kaplan D (2003) Aspiration pneumonia and dysphagia in the elderly. Chest 124, 328-336.","DOI":"10.1378\/chest.124.1.328"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Teramoto S, Yoshida K, Hizawa N (2015) Update on the pathogenesis and management of pneumonia in the elderly-roles of aspiration pneumonia. Respir Investig 53, 178-184.","DOI":"10.1016\/j.resinv.2015.01.003"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Manabe T, Teramoto S, Tamiya N, Okochi J, Hizawa N (2015) Risk factors for aspiration pneumonia in older adults. PLoS One 10, e0140060.","DOI":"10.1371\/journal.pone.0140060"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Kulkarni DP, Kamath VD, Stewart JT (2017) Swallowing disorders in schizophrenia. Dysphagia 32, 467-471.","DOI":"10.1007\/s00455-017-9802-6"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Leibovitz A, Baumoehl Y, Lubart E, Yaina A, Platinovitz N, Segal R (2007) Dehydration among long-term care elderly patients with oropharyngeal dysphagia. Gerontology 53, 179-183.","DOI":"10.1159\/000099144"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Serra-Prat M, Palomera M, Gomez C, Sar-Shalom D, Saiz A, Montoya JG et al. (2012) Oropharyngeal dysphagia as a risk factor for malnutrition and lower respiratory tract infection in independently living older persons: a population-based prospective study. Age Ageing 41, 376-381.","DOI":"10.1093\/ageing\/afs006"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Lautenbacher S (2012) Experimental approaches in the study of pain in the elderly. Pain Med 13 Suppl 2, S44-50.","DOI":"10.1111\/j.1526-4637.2012.01326.x"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Momosaki R, Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Abo M (2015) Effect of dysphagia rehabilitation on oral intake in elderly patients with aspiration pneumonia. Geriatr Gerontol Int 15, 694-699.","DOI":"10.1111\/ggi.12333"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Tominaga M, Tominaga T (2005) Structure and function of TRPV1. Pflugers Arch 451, 143-150.","DOI":"10.1007\/s00424-005-1457-8"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Ebihara T, Takahashi H, Ebihara S, Okazaki T, Sasaki T, Watando A et al. (2005) Capsaicin troche for swallowing dysfunction in older people. J Am Geriatr Soc 53, 824-828.","DOI":"10.1111\/j.1532-5415.2005.53261.x"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Jin Y, Sekizawa K, Fukushima T, Morikawa M, Nakazawa H, Sasaki H (1994) Capsaicin desensitization inhibits swallowing reflex in guinea pigs. Am J Respir Crit Care Med 149, 261-263.","DOI":"10.1164\/ajrccm.149.1.7509247"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Ebihara S, Maruyama Y, Ebihara T, Oshiro T, Kohzuki M (2010) Red wine polyphenols and swallowing reflex in dysphagia. Geriatr Gerontol Int 10, 329-330.","DOI":"10.1111\/j.1447-0594.2010.00636.x"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Tsujimura T, Udemgba C, Inoue M, Canning BJ (2013) Laryngeal and tracheal afferent nerve stimulation evokes swallowing in anaesthetized guinea pigs. J Physiol 591, 4667-4679.","DOI":"10.1113\/jphysiol.2013.256024"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Ebihara T, Ebihara S, Watando A, Okazaki T, Asada M, Ohrui T et al. (2006) Effects of menthol on the triggering of the swallowing reflex in elderly patients with dysphagia. Br J Clin Pharmacol 62, 369-371.","DOI":"10.1111\/j.1365-2125.2006.02666.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Rofes L, Arreola V, Martin A, Clav\u00e9 P (2014) Effect of oral piperine on the swallow response of patients with oropharyngeal dysphagia. J Gastroenterol 49, 1517-1523.","DOI":"10.1007\/s00535-013-0920-0"},{"key":"18","doi-asserted-by":"publisher","unstructured":"18. Alvarez-Berdugo D, Rofes L, Arreola V, Martin A, Molina L, Clav\u00e9 P (2018) A comparative study on the therapeutic effect of TRPV1, TRPA1, and TRPM8 agonists on swallowing dysfunction associated with aging and neurological diseases. Neurogastroenterol Motil 30, doi: 10.1111\/nmo.13185.","DOI":"10.1111\/nmo.13185"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. B\u00fclow M, Olsson R, Ekberg O (2003) Videoradiographic analysis of how carbonated thin liquids and thickened liquids affect the physiology of swallowing in subjects with aspiration on thin liquids. Acta Radiol 44, 366-372.","DOI":"10.1034\/j.1600-0455.2003.00100.x"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Pelletier CA, Lawless HT (2003) Effect of citric acid and citric acid-sucrose mixtures on swallowing in neurogenic oropharyngeal dysphagia. Dysphagia 18, 231-241.","DOI":"10.1007\/s00455-003-0013-y"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Sdravou K, Walshe M, Dagdilelis L (2012) Effects of carbonated liquids on oropharyngeal swallowing measures in people with neurogenic dysphagia. Dysphagia 27, 240-250.","DOI":"10.1007\/s00455-011-9359-8"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Tsujimura T, Ueha R, Yoshihara M, Takei E, Nagoya K, Shiraishi N et al. (2019) Involvement of the epithelial sodium channel in initiation of mechanically evoked swallows in anaesthetized rats. J Physiol 597, 2949-2963.","DOI":"10.1113\/JP277895"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Ding P, Campbell-Malone R, Holman SD, Lukasik SL, Fukuhara T, Gierbolini-Norat EM et al. (2013) Unilateral superior laryngeal nerve lesion in an animal model of dysphagia and its effect on sucking and swallowing. Dysphagia 28, 404-412.","DOI":"10.1007\/s00455-013-9448-y"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Jafari S, Prince RA, Kim DY, Paydarfar D (2003) Sensory regulation of swallowing and airway protection: a role for the internal superior laryngeal nerve in humans. J Physiol 550, 287-304.","DOI":"10.1113\/jphysiol.2003.039966"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Jean A (2001) Brain stem control of swallowing: neuronal network and cellular mechanisms. Physiol Rev 81, 929-969.","DOI":"10.1152\/physrev.2001.81.2.929"},{"key":"26","unstructured":"26. Wang YT, Bieger D (1991) Role of solitarial GABAergic mechanisms in control of swallowing. Am J Physiol 261, R639-646."},{"key":"27","unstructured":"27. Jean A, Kessler JP, Tell F (1994) Nucleus tractus solitarii and deglutition: Monoamines, excitatory amino acids, and cellular properties. Nucleus of the solitary tract, 361-375."},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Kern MK, Jaradeh S, Arndorfer RC, Shaker R (2001) Cerebral cortical representation of reflexive and volitional swallowing in humans. Am J Physiol Gastrointest Liver Physiol 280, G354-360.","DOI":"10.1152\/ajpgi.2001.280.3.G354"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Suzuki M, Asada Y, Ito J, Hayashi K, Inoue H, Kitano H (2003) Activation of cerebellum and basal ganglia on volitional swallowing detected by functional magnetic resonance imaging. Dysphagia 18, 71-77.","DOI":"10.1007\/s00455-002-0088-x"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Satow T, Ikeda A, Yamamoto J, Begum T, Thuy DH, Matsuhashi M et al. (2004) Role of primary sensorimotor cortex and supplementary motor area in volitional swallowing: a movement-related cortical potential study. Am J Physiol Gastrointest Liver Physiol 287, G459-470.","DOI":"10.1152\/ajpgi.00323.2003"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Humbert IA, Robbins J (2007) Normal swallowing and functional magnetic resonance imaging: a systematic review. Dysphagia 22, 266-275.","DOI":"10.1007\/s00455-007-9080-9"},{"key":"32","unstructured":"32. Singh A, Kate MP, Nair MD, Kesavadas C, Kapilamoorthy TR (2011) Bilateral perisylvian infarct: a rare cause and a rare occurrence. Singapore Med J 52, e62-65."},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. S\u00f6r\u00f6s P, Al-Otaibi F, Wong SW, Shoemaker JK, Mirsattari SM, Hachinski V et al. (2011) Stuttered swallowing: electric stimulation of the right insula interferes with water swallowing. A case report. BMC Neurol 11, 20.","DOI":"10.1186\/1471-2377-11-20"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Tsujimura T, Tsuji K, Magara J, Sakai S, Suzuki T, Nakamura Y et al. (2016) Differential response properties of peripherally and cortically evoked swallows by electrical stimulation in anesthetized rats. Brain Res Bull 122, 12-18.","DOI":"10.1016\/j.brainresbull.2016.02.015"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Tsujimura T, Suzuki T, Yoshihara M, Sakai S, Koshi N, Ashiga H et al. (2018) Involvement of hypoglossal and recurrent laryngeal nerves on swallowing pressure. J Appl Physiol (1985) 124, 1148-1154.","DOI":"10.1152\/japplphysiol.00944.2017"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Zoungrana OR, Amri M, Car A, Roman C (1997) Intracellular activity of motoneurons of the rostral nucleus ambiguus during swallowing in sheep. J Neurophysiol 77, 909-922.","DOI":"10.1152\/jn.1997.77.2.909"},{"key":"37","unstructured":"37. Spieker MR (2000) Evaluating dysphagia. Am Fam Physician 61, 3639-3648."},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Sim\u00f5es J, Rom\u00e3o J, Cunha A, Paiva S, Migu\u00e9is A (2017) Neck pain and acute dysphagia. Dysphagia 32, 123-125.","DOI":"10.1007\/s00455-016-9764-0"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Ariji Y, Gotoh M, Kimura Y, Naitoh M, Kurita K, Natsume N et al. (2002) Odontogenic infection pathway to the submandibular space: imaging assessment. Int J Oral Maxillofac Surg 31, 165-169.","DOI":"10.1054\/ijom.2001.0190"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Fornari F, Farr\u00e9 R, van Malenstein H, Blondeau K, Callegari-Jacques SM, Barros SG (2008) Nutcracker oesophagus: association with chest pain and dysphagia controlling for gastro-oesophageal reflux. Dig Liver Dis 40, 717-722.","DOI":"10.1016\/j.dld.2008.02.018"},{"key":"41","unstructured":"41. Katz PO, Gerson LB, Vela MF (2013) Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol 108, 308-328; quiz 329."},{"key":"42","doi-asserted-by":"crossref","unstructured":"42. Gilheaney \u00d3, B\u00e9chet S, Kerr P, Kenny C, Smith S, Kouider R et al. (2018) The prevalence of oral stage dysphagia in adults presenting with temporomandibular disorders: a systematic review and meta-analysis. Acta Odontol Scand 76, 448-458.","DOI":"10.1080\/00016357.2018.1424936"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43. Fassicollo CE, Machado BCZ, Garcia DM, de Fel\u00edcio CM (2019) Swallowing changes related to chronic temporomandibular disorders. Clin Oral Investig 23, 3287-3296.","DOI":"10.1007\/s00784-018-2760-z"},{"key":"44","unstructured":"44. Goldstein LB, Last FC, Salerno VM (1997) Prevalence of hyperactive digastric muscles during swallowing as measured by electromyography in patients with myofascial pain dysfunction syndrome. Funct Orthod 14, 18-22, 24."},{"key":"45","doi-asserted-by":"crossref","unstructured":"45. Vaiman M, Nahlieli O, Eliav E (2006) Oynophagia in patients after dental extraction: surface electromyography study. Head Face Med 2, 34.","DOI":"10.1186\/1746-160X-2-34"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46. Wang K, Arendt-Nielsen L, Svensson P (2002) Capsaicin-induced muscle pain alters the excitability of the human jaw-stretch reflex. J Dent Res 81, 650-654.","DOI":"10.1177\/154405910208100915"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47. Cairns BE, Sessle BJ, Hu JW (1998) Evidence that excitatory amino acid receptors within the temporomandibular joint region are involved in the reflex activation of the jaw muscles. J Neurosci 18, 8056-8064.","DOI":"10.1523\/JNEUROSCI.18-19-08056.1998"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48. Peddireddy A, Wang K, Svensson P, Arendt-Nielsen L (2005) Effect of experimental posterior temporalis muscle pain on human brainstem reflexes. Clin Neurophysiol 116, 1611-1620.","DOI":"10.1016\/j.clinph.2005.02.022"},{"key":"49","doi-asserted-by":"crossref","unstructured":"49. Zoungrana OR, Lamkadem M, Amri M, Car A, Roman C (2000) Effects of lingual nerve afferents on swallowing in sheep. Exp Brain Res 132, 500-509.","DOI":"10.1007\/s002210000361"},{"key":"50","doi-asserted-by":"crossref","unstructured":"50. Tsujimura T, Kitagawa J, Ueda K, Iwata K (2009) Inhibition of swallowing reflex following phosphorylation of extracellular signal-regulated kinase in nucleus tractus solitarii neurons in rats with masseter muscle nociception. Neurosci Lett 450, 361-364.","DOI":"10.1016\/j.neulet.2008.12.008"},{"key":"51","doi-asserted-by":"crossref","unstructured":"51. Tsujimura T, Kondo M, Kitagawa J, Tsuboi Y, Saito K, Tohara H et al. (2009) Involvement of ERK phosphorylation in brainstem neurons in modulation of swallowing reflex in rats. J Physiol 587, 805-817.","DOI":"10.1113\/jphysiol.2008.165324"},{"key":"52","doi-asserted-by":"crossref","unstructured":"52. Ji RR, Baba H, Brenner GJ, Woolf CJ (1999) Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat Neurosci 2, 1114-1119.","DOI":"10.1038\/16040"},{"key":"53","doi-asserted-by":"crossref","unstructured":"53. Imbe H, Dubner R, Ren K (1999) Masseteric inflammation-induced Fos protein expression in the trigeminal interpolaris\/caudalis transition zone: contribution of somatosensory-vagal-adrenal integration. Brain Res 845, 165-175.","DOI":"10.1016\/S0006-8993(99)01913-7"},{"key":"54","doi-asserted-by":"crossref","unstructured":"54. Boscan P, Paton JF (2002) Integration of cornea and cardiorespiratory afferents in the nucleus of the solitary tract of the rat. Am J Physiol Heart Circ Physiol 282, H1278-1287.","DOI":"10.1152\/ajpheart.00678.2001"},{"key":"55","doi-asserted-by":"crossref","unstructured":"55. Yamazaki Y, Ren K, Shimada M, Iwata K (2008) Modulation of paratrigeminal nociceptive neurons following temporomandibular joint inflammation in rats. Exp Neurol 214, 209-218.","DOI":"10.1016\/j.expneurol.2008.08.005"},{"key":"56","doi-asserted-by":"crossref","unstructured":"56. Chun YH, Ro JY (2010) Electrophysiological characterization of the rat trigeminal caudalis (Vc)neurons following intramuscular injection of capsaicin. Neurosci Lett 469, 289-293.","DOI":"10.1016\/j.neulet.2009.10.012"},{"key":"57","doi-asserted-by":"crossref","unstructured":"57. Clements JR, Magnusson KR, Hautman J, Beitz AJ (1991) Rat tooth pulp projections to spinal trigeminal subnucleus caudalis are glutamate-like immunoreactive. J Comp Neurol 309, 281-288.","DOI":"10.1002\/cne.903090209"},{"key":"58","doi-asserted-by":"crossref","unstructured":"58. Sugimoto T, Fujiyoshi Y, He YF, Xiao C, Ichikawa H (1997) Trigeminal primary projection to the rat brain stem sensory trigeminal nuclear complex and surrounding structures revealed by anterograde transport of cholera toxin B subunit-conjugated and Bandeiraea simplicifolia isolectin B4-conjugated horseradish peroxidase. Neurosci Res 28, 361-371.","DOI":"10.1016\/S0168-0102(97)00064-3"},{"key":"59","unstructured":"59. Kessler JP, Jean A (1985) Identification of the medullary swallowing regions in the rat. Exp Brain Res 57, 256-263."},{"key":"60","doi-asserted-by":"crossref","unstructured":"60. de Sousa Buck H, Caous CA, Lindsey CJ (2001) Projections of the paratrigeminal nucleus to the ambiguus, rostroventrolateral and lateral reticular nuclei, and the solitary tract. Auton Neurosci 87, 187-200.","DOI":"10.1016\/S1566-0702(00)00259-9"},{"key":"61","doi-asserted-by":"crossref","unstructured":"61. Foster AC, Kemp JA (2006) Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol 6, 7-17.","DOI":"10.1016\/j.coph.2005.11.005"},{"key":"62","doi-asserted-by":"crossref","unstructured":"62. Tsujimura T, Inoue M, Iwata K (2011) Neural mechanisms of swallowing inhibition following noxious orofacial stimulation. J Oral Biosci 53, 137-142.","DOI":"10.1016\/S1349-0079(11)80016-2"}],"container-title":["Journal of Oral Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/josnusd\/62\/2\/62_19-0408\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,28]],"date-time":"2020-03-28T03:50:26Z","timestamp":1585367426000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/josnusd\/62\/2\/62_19-0408\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":62,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.2334\/josnusd.19-0408","relation":{},"ISSN":["1343-4934","1880-4926"],"issn-type":[{"type":"print","value":"1343-4934"},{"type":"electronic","value":"1880-4926"}],"subject":[],"published":{"date-parts":[[2020]]}}}