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American Society of Anesthesiologists Task Force on Sedation and Analgesia by Non-Anesthesiologists (2002) Practice guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology 96, 1004-1017.","DOI":"10.1097\/00000542-200204000-00031"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Eichhorn V, Henzler D, Murphy MF (2010) Standardizing care and monitoring for anesthesia or procedural sedation delivered outside the operating room. Curr Opin Anaesthesiol 23, 494-499.","DOI":"10.1097\/ACO.0b013e32833b9c9f"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Southerland JH, Brown LR (2016) Conscious intravenous sedation in dentistry: a review of current therapy. Dent Clin North Am 60, 309-346.","DOI":"10.1016\/j.cden.2015.11.009"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Frank LR, Strote J, Hauff SR, Bigelow SK, Fay K (2006) Propofol by infusion protocol for ed procedural sedation. 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Steiner C, Steurer MP, Mueller D, Zueger M, Dullenkopf A (2016) Midazolam plasma concentration after anesthesia premedication in clinical routine - an observational study: midazolam plasma concentration after anesthesia premedication. BMC Anesthesiol 16, 105.","DOI":"10.1186\/s12871-016-0262-6"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Borkett KM, Riff DS, Schwartz HI, Winkle PJ, Pambianco DJ, Lees JP et al. (2015) A phase IIa, randomized, double-blind study of remimazolam (CNS 7056) versus midazolam for sedation in upper gastrointestinal endoscopy. Anesth Analg 120, 771-780.","DOI":"10.1213\/ANE.0000000000000548"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Keam SJ (2020) Remimazolam: first approval. Drugs 80, 625-633.","DOI":"10.1007\/s40265-020-01299-8"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Masui K (2020) Remimazolam besilate, a benzodiazepine, has been approved for general anesthesia!! 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(2020) The efficacy and safety of remimazolam tosylate versus propofol in patients undergoing colonoscopy: a multicentered, randomized, positive-controlled, phase III clinical trial. Am J Transl Res 12, 4594-4603."},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Chen SH, Yuan TM, Zhang J, Bai H, Tian M, Pan CX et al. (2020) Remimazolam tosilate in upper gastrointestinal endoscopy: a multicenter, randomized, non-inferiority, phase III trial. J Gastroenterol Hepatol 36, 474-481.","DOI":"10.1111\/jgh.15188"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Johnson KB (2012) New horizons in sedative hypnotic drug development: fast, clean, and soft. Anesth Analg 115, 220-222.","DOI":"10.1213\/ANE.0b013e31825ef8d7"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Chitilian HV, Eckenhoff RG, Raines DE (2013) Anesthetic drug development: novel drugs and new approaches. 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