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Schalk-van der Weide Y, Beemer FA, Faber JA, Bosman F (1994) Symptomatology of patients with oligodontia. J Oral Rehabil 21, 247-261.","DOI":"10.1111\/j.1365-2842.1994.tb01141.x"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Neal JJ, Bowden DE (1988) The diagnostic value of panoramic radiographs in children aged nine to ten years. Br J Orthod 15, 193-197.","DOI":"10.1179\/bjo.15.3.193"},{"key":"19","unstructured":"19. Borzabadi-Farahani A, Borzabadi-Farahani A, Eslamipour F (2009) Orthodontic treatment needs in an urban Iranian population, an epidemiological study of 11-14 year old children. Eur J Paediatr Dent 10, 69-74."},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Wisth PJ, Thunold K, B&ouml;e OE (1974) Frequency of hypodontia in relation to tooth size and dental arch width. Acta Odontol Scand 32, 201-206.","DOI":"10.3109\/00016357409002548"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. 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