{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T16:52:42Z","timestamp":1768150362558,"version":"3.49.0"},"reference-count":31,"publisher":"Nihon University School of Dentistry","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Sci"],"published-print":{"date-parts":[[2014]]},"DOI":"10.2334\/josnusd.56.253","type":"journal-article","created":{"date-parts":[[2014,12,11]],"date-time":"2014-12-11T23:23:00Z","timestamp":1418340180000},"page":"253-260","source":"Crossref","is-referenced-by-count":83,"title":["MicroRNA expression in inflamed and noninflamed gingival tissues from Japanese patients"],"prefix":"10.2334","volume":"56","author":[{"given":"Yorimasa","family":"Ogata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sari","family":"Matsui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayako","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liming","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Takai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1160","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Pihlstrom BL, Michalowicz BS, Johnson NW (2005) Periodontal diseases. Lancet 366, 1809-1820.","DOI":"10.1016\/S0140-6736(05)67728-8"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Kato A, Imai K, Ochiai K, Ogata Y (2013) Higher prevalence of Epstein\u2013Barr virus DNA in deeper periodontal pockets of chronic periodontitis in Japanese patients. PLoS One 8, e71990.","DOI":"10.1371\/journal.pone.0071990"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Seymour GJ, Powell RN, Cole KL, Aitken JF, Brooks D, Beckman I et al. (1983) Experimental gingivitis in humans. A histochemical and immunological characterization of the lymphoid cell subpopulations. J Periodontal Res 18, 375-385.","DOI":"10.1111\/j.1600-0765.1983.tb00373.x"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Maqbool R, Hussain MU (2014) MicroRNAs and human diseases: diagnostic and therapeutic potential. Cell Tissue Res DOI 10.1007\/s00441-013-1787-3.","DOI":"10.1007\/s00441-013-1787-3"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Kozomara A, Griffiths-Jones S (2011) miRBase: annotating high confidence microRNAs using deep sequencing data. Nucleic Acids Res 39, D152-157.","DOI":"10.1093\/nar\/gkq1027"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Nakasa T, Miyaki S, Okubo A, Hashimoto M, Nishida K, Ochi M et al. (2008) Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis Rheum 58, 1284-1292.","DOI":"10.1002\/art.23429"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Hung PS, Chen FC, Kuang SH, Kao SY, Lin SC, Chang KW (2010) miR-146a induces differentiation of periodontal ligament cells. J Dent Res 89, 252-257.","DOI":"10.1177\/0022034509357411"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Nahid MA, Rivera M, Lucas A, Chan EKL, Kesavalu L (2011) Polymicrobial infection with periodontal pathogens specifically enhances microRNA miR-146a in ApoE-\/- mice during experimental periodontal disease. Infect Immun 79, 1597-1605.","DOI":"10.1128\/IAI.01062-10"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Park MG, Kim JS, Park SY, Lee SA, Kim HJ, Kim CS et al. (2014) MicroRNA-27 promotes the differentiation of odontoblastic cell by targeting APC and activating Wnt\/\u03b2-catenin signaling. Gene 538, 266-272.","DOI":"10.1016\/j.gene.2014.01.045"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Xie YF, Shu R, Jiang SY, Liu DL, Zhang XL (2011) Comparison of microRNA profiles of human periodontal diseased and healthy gingival tissues. Int J Oral Sci 3, 125-134.","DOI":"10.4248\/IJOS11046"},{"key":"11","unstructured":"11. Lee YH, Hee SN, Jeong SY, Jeong SH, Park HR, Chung J (2011) Comparison of inflammatory microRNA expression in healthy and periodontitis tissues. Biocell 35, 42-49."},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Stoecklin-Wasmer C, Guarnieri P, Celenti R, Demmer RT, Kebschull M, Papapanou PN (2012) MicroRNAs and their target genes in gingival tissues. J Dent Res 91, 934-940.","DOI":"10.1177\/0022034512456551"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Perri R, Nares S, Zhang S, Barros SP, Offenbacher A (2012) MicroRNA modulation in obesity and periodontitis. J Dent Res 91, 33-38.","DOI":"10.1177\/0022034511425045"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Xie Y, Shu R, Jiang S, Liu D, Ni J, Zhang X (2013) MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts. J Inflammation 10, 20.","DOI":"10.1186\/1476-9255-10-20"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Ogata Y, Niisato N, Sakurai T, Furuyama S, Sugiya H (1995) Comparison of the characteristics of human gingival fibroblasts and periodontal ligament cells. J Periodontol 66, 1025-1031.","DOI":"10.1902\/jop.1995.66.12.1025"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Nakao S, Ogata Y, Shimizu E, Yamazaki M, Furuyama S, Sugiya H (2002) Tumor necrosis factor \u03b1 (TNF-\u03b1)-induced prostaglandin E<sub>2<\/sub> release is mediated by the activation of cyclooxygenase-2 (COX-2) transcription via NF\u03baB in human gingival fibroblasts. Mol Cell Biochem 238, 11-18.","DOI":"10.1023\/A:1019927616000"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Nakao S, Ogata Y, Yamamoto Y, Furuyama S, Sugiya H (2004) Platelet-derived growth factor-induced arachidonic acid release for enhancement of prostaglandin E<sub>2<\/sub> synthesis in human gingival fibroblasts pretreated with interleukin-1\u03b2. J Cell Biochem 92, 579-590.","DOI":"10.1002\/jcb.20086"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Sato K, Yoshimura A, Kaneko T, Ukai T, Ozaki Y, Nakamura H et al. (2012) A single nucleotide polymorphism in 3\u2019-untranslated region contributes to the regulation of Toll-like receptor 4 translation. J Biol Chem 287, 25163-25172.","DOI":"10.1074\/jbc.M111.338426"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Sugatani T, Hruska KA (2007) MicroRNA-223 is a key factor in osteoclast differentiation. J Cell Biochem 101, 996-999.","DOI":"10.1002\/jcb.21335"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Eyholzer M, Schmid S, Schardt JA, Haefliger S, Mueller BU, Pabst T (2010) Complexity of miR-223 regulation by CEBPA in human AML. Leuk Res 34, 672-676.","DOI":"10.1016\/j.leukres.2009.11.019"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Fulci V, Scappucci G, Sebastiani GD, Giannitti C, Franceschini D, Meloni F et al. (2010) miR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis. Hum Immunol 71, 206-211.","DOI":"10.1016\/j.humimm.2009.11.008"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Rangrez AY, M\u2019Baya-Moutoula E, Metzinger-Le Meuth V, Henaut L, Djelouat MS, Benchitrit J et al. (2012) Inorganic phosphate accelerates the migration of vascular smooth muscle cells: evidence for the involvement of miR-223. PLoS One 7, e47807.","DOI":"10.1371\/journal.pone.0047807"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Zhuang G, Meng C, Guo X, Cheruku PS, Shi L, Xu H et al. (2012) A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation. Circulation 125, 2892-2903.","DOI":"10.1161\/CIRCULATIONAHA.111.087817"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Pan Y, Liang H, Liu H, Li D, Chen X, Li L et al. (2014) Platelet-secreted microRNA-223 promotes endothelial cell apoptosis induced by advanced glycation end products via targeting the insulin-like growth factor 1 receptor. J Immunol 192, 437-446.","DOI":"10.4049\/jimmunol.1301790"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Laffont B, Corduan A, Pl\u00e9 H, Duchez AC, Cloutier N, Boilard E et al. (2013) Activated platelets can deliver mRNA regulatory Ago2\u2022microRNA complexes to endothelial cells via microparticles. Blood 122, 253-261.","DOI":"10.1182\/blood-2013-03-492801"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Zhou B, Wang S, Mayr C, Bartel DP, Lodish HF (2007) miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proc Natl Acad Sci U S A 104, 7080-7085.","DOI":"10.1073\/pnas.0702409104"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Roderburg C, Luedde M, Cardenas DV, Vucur M, Scholten D, Frey N et al. (2013) Circulating microRNA-150 serum levels predict survival in patients with critical illness and sepsis. PLoS one 8, e54612.","DOI":"10.1371\/journal.pone.0054612"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Bezman NA, Chakraborty T, Bender T, Lanier LL (2011) miR-150 regulates the development of NK and iNKT cells. J Exp Med 208, 2717-2731.","DOI":"10.1084\/jem.20111386"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Kojo S, Adachi Y, Keino H, Taniguchi M, Sumida T (2001) Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases. Arthritis Rheum 44, 1127-1138.","DOI":"10.1002\/1529-0131(200105)44:5<1127::AID-ANR194>3.0.CO;2-W"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Fu Y, Liu X, Zhou N, Du L, Sun Y, Zhang X et al. (2014) MicroRNA-200b stimulates tumour growth in TGFBR2-null colorectal cancers by negatively regulating p27\/kip1. J Cell Physiol 229, 772-782.","DOI":"10.1002\/jcp.24497"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Bai JX, Yan B, Zhao ZN, Xiao X, Qin W, Zhang R et al. (2013) Tamoxifen represses miR-200 microRNAs and promotes epithelial-to-mesenchymal transition by up-regulating c-Myc in endometrial carcinoma cell lines. Endocrinol 154, 635-645.","DOI":"10.1210\/en.2012-1607"}],"container-title":["Journal of Oral Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/josnusd\/56\/4\/56_253\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T01:58:53Z","timestamp":1498183133000},"score":1,"resource":{"primary":{"URL":"http:\/\/jlc.jst.go.jp\/DN\/JST.JSTAGE\/josnusd\/56.253?lang=en&from=CrossRef&type=abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.2334\/josnusd.56.253","relation":{},"ISSN":["1343-4934","1880-4926"],"issn-type":[{"value":"1343-4934","type":"print"},{"value":"1880-4926","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}