{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:28:40Z","timestamp":1758817720372},"reference-count":33,"publisher":"American Diabetes Association","issue":"3","license":[{"start":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T00:00:00Z","timestamp":1630022400000},"content-version":"vor","delay-in-days":3483,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,3,1]]},"abstract":"<jats:sec><jats:title \/><jats:p>Short interbirth interval has been associated with maternal complications and childhood autism and leukemia, possibly due to deficiencies in maternal micronutrients at conception or increased exposure to sibling infections. A possible association between interbirth interval and subsequent risk of childhood type 1 diabetes has not been investigated. A secondary analysis of 14 published observational studies of perinatal risk factors for type 1 diabetes was conducted. Risk estimates of diabetes by category of interbirth interval were calculated for each study. Random effects models were used to calculate pooled odds ratios (ORs) and investigate heterogeneity between studies. Overall, 2,787 children with type 1 diabetes were included. There was a reduction in the risk of childhood type 1 diabetes in children born to mothers after interbirth intervals &amp;lt;3 years compared with longer interbirth intervals (OR 0.82 [95% CI 0.72\u20130.93]). Adjustments for various potential confounders little altered this estimate. In conclusion, there was evidence of a 20% reduction in the risk of childhood diabetes in children born to mothers after interbirth intervals &amp;lt;3 years.<\/jats:p><\/jats:sec>","DOI":"10.2337\/db11-1000","type":"journal-article","created":{"date-parts":[[2012,2,9]],"date-time":"2012-02-09T06:22:26Z","timestamp":1328768546000},"page":"702-707","update-policy":"http:\/\/dx.doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":6,"title":["Interbirth Interval Is Associated With Childhood Type 1 Diabetes Risk"],"prefix":"10.2337","volume":"61","author":[{"given":"Chris R.","family":"Cardwell","sequence":"first","affiliation":[{"name":"Centre for Public Health, Queen\u2019s University Belfast, Belfast, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jannet","family":"Svensson","sequence":"additional","affiliation":[{"name":"Pediatric Department, Glostrup University Hospital, Glostrup, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Waldhoer","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Medical University of Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johnny","family":"Ludvigsson","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Diabetes Research Centre, Linkoping University, Linkoping, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaiva","family":"Sadauskait\u0117-Kuehne","sequence":"additional","affiliation":[{"name":"Institute of Endocrinology of Lithuanian University of Health Science, Kaunas, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine L.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Kolling Institute of Medical Research, University of Sydney, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger C.","family":"Parslow","sequence":"additional","affiliation":[{"name":"Paediatric Epidemiology Group, University of Leeds, Leeds, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma J.K.","family":"Wadsworth","sequence":"additional","affiliation":[{"name":"Centre for Occupational and Health Psychology, Cardiff University, Cardiff, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girts","family":"Brigis","sequence":"additional","affiliation":[{"name":"Department of Public Health and Epidemiology, Riga Stradins University, Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brone","family":"Urbonait\u0117","sequence":"additional","affiliation":[{"name":"Institute of Endocrinology, Kaunas University of Medicine, Kaunas, Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edith","family":"Schober","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Medical University of Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Devoti","sequence":"additional","affiliation":[{"name":"Department of Social Sciences and Communication, University of Lecce, Lecce, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constantin","family":"Ionescu-Tirgoviste","sequence":"additional","affiliation":[{"name":"Nutrition and Metabolic Diseases Clinic, N. 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