{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:48:58Z","timestamp":1767984538124,"version":"3.49.0"},"reference-count":20,"publisher":"American Diabetes Association","issue":"5","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,5,1]]},"DOI":"10.2337\/db14-0003","type":"journal-article","created":{"date-parts":[[2014,4,22]],"date-time":"2014-04-22T19:50:11Z","timestamp":1398196211000},"page":"1448-1450","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":4,"title":["Amyloid and the Macrophage: It\u2019s All About Local Production of IL-1\u03b2"],"prefix":"10.2337","volume":"63","author":[{"given":"Katarzyna A.","family":"Broniowska","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Corbett","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","published-online":{"date-parts":[[2014,4,12]]},"reference":[{"key":"2022031223181108700_B1","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1126\/science.3086977","article-title":"Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans","volume":"232","author":"Bendtzen","year":"1986","journal-title":"Science"},{"key":"2022031223181108700_B2","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1111\/j.1398-9995.1986.tb02025.x","article-title":"Mechanisms of pancreatic islet cell destruction. Dose-dependent cytotoxic effect of soluble blood mononuclear cell mediators on isolated islets of Langerhans","volume":"41","author":"Mandrup-Poulsen","year":"1986","journal-title":"Allergy"},{"key":"2022031223181108700_B3","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1042\/bj2870229","article-title":"Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction","volume":"287","author":"Corbett","year":"1992","journal-title":"Biochem J"},{"key":"2022031223181108700_B4","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1172\/JCI116129","article-title":"Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide","volume":"90","author":"Corbett","year":"1992","journal-title":"J Clin Invest"},{"key":"2022031223181108700_B5","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/0014-5793(90)80502-A","article-title":"Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism","volume":"276","author":"Southern","year":"1990","journal-title":"FEBS Lett"},{"key":"2022031223181108700_B6","doi-asserted-by":"crossref","first-page":"3167","DOI":"10.1210\/endo-129-6-3167","article-title":"Interleukin-1 beta-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase","volume":"129","author":"Welsh","year":"1991","journal-title":"Endocrinology"},{"key":"2022031223181108700_B7","doi-asserted-by":"crossref","first-page":"21351","DOI":"10.1016\/S0021-9258(18)54642-1","article-title":"Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion","volume":"266","author":"Corbett","year":"1991","journal-title":"J Biol Chem"},{"key":"2022031223181108700_B8","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0168-8227(89)90006-5","article-title":"In vivo administration of interleukin-1 inhibits glucose-stimulated insulin release","volume":"7","author":"Wang","year":"1989","journal-title":"Diabetes Res Clin Pract"},{"key":"2022031223181108700_B9","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/BF00401200","article-title":"Repetitive in vivo treatment with human recombinant interleukin-1 beta modifies beta-cell function in normal rats","volume":"35","author":"Wogensen","year":"1992","journal-title":"Diabetologia"},{"key":"2022031223181108700_B10","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1073\/pnas.87.3.968","article-title":"Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1","volume":"87","author":"Jacob","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"key":"2022031223181108700_B11","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1074\/jbc.273.5.2493","article-title":"Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic beta cells develop insulin-dependent diabetes without insulitis","volume":"273","author":"Takamura","year":"1998","journal-title":"J Biol Chem"},{"key":"2022031223181108700_B12","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/nri2925","article-title":"Type 2 diabetes as an inflammatory disease","volume":"11","author":"Donath","year":"2011","journal-title":"Nat Rev Immunol"},{"key":"2022031223181108700_B13","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1172\/JCI200215318","article-title":"Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets","volume":"110","author":"Maedler","year":"2002","journal-title":"J Clin Invest"},{"key":"2022031223181108700_B14","doi-asserted-by":"crossref","DOI":"10.2337\/db13-0863","article-title":"Resident macrophages mediate islet amyloid polypeptide\u2013induced islet IL-1\u03b2 production and \u03b2-cell dysfunction","author":"Westwell-Roper","year":"2014;63:1698\u20131711","journal-title":"Diabetes"},{"key":"2022031223181108700_B15","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1038\/ni.1935","article-title":"Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1\u03b2 in type 2 diabetes","volume":"11","author":"Masters","year":"2010","journal-title":"Nat Immunol"},{"key":"2022031223181108700_B16"},{"key":"2022031223181108700_B17"},{"key":"2022031223181108700_B18","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1172\/JCI844","article-title":"IL-1 produced and released endogenously within human islets inhibits beta cell function","volume":"102","author":"Arnush","year":"1998","journal-title":"J Clin Invest"},{"key":"2022031223181108700_B19","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.4049\/jimmunol.160.6.2684","article-title":"Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes","volume":"160","author":"Arnush","year":"1998","journal-title":"J Immunol"},{"key":"2022031223181108700_B20","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1084\/jem.181.2.559","article-title":"Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase","volume":"181","author":"Corbett","year":"1995","journal-title":"J Exp Med"}],"container-title":["Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.org\/diabetes\/diabetes\/article-pdf\/63\/5\/1448\/577617\/1448.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article-pdf\/63\/5\/1448\/577617\/1448.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T09:39:59Z","timestamp":1689154799000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article\/63\/5\/1448\/34128\/Amyloid-and-the-Macrophage-It-s-All-About-Local"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,12]]},"references-count":20,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2014,4,12]]},"published-print":{"date-parts":[[2014,5,1]]}},"URL":"https:\/\/doi.org\/10.2337\/db14-0003","relation":{},"ISSN":["0012-1797","1939-327X"],"issn-type":[{"value":"0012-1797","type":"print"},{"value":"1939-327X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,12]]}}}