{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T10:48:27Z","timestamp":1781088507608,"version":"3.54.1"},"reference-count":39,"publisher":"American Diabetes Association","issue":"1","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"vor","delay-in-days":243,"URL":"http:\/\/www.diabetesjournals.org\/site\/license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81900268"],"award-info":[{"award-number":["81900268"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970257"],"award-info":[{"award-number":["81970257"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science and Technology Innovation Plan of Hubei Province","award":["2016ACA151"],"award-info":[{"award-number":["2016ACA151"]}]},{"DOI":"10.13039\/501100003397","name":"Huazhong University of Science and Technology","doi-asserted-by":"crossref","award":["2016JCTD107"],"award-info":[{"award-number":["2016JCTD107"]}],"id":[{"id":"10.13039\/501100003397","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People\u2019s Republic of China","doi-asserted-by":"crossref","award":["2016 YFA0101100"],"award-info":[{"award-number":["2016 YFA0101100"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":["Diabetes"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.2337\/db19-0635","type":"journal-article","created":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T23:25:17Z","timestamp":1572650717000},"page":"99-111","update-policy":"https:\/\/doi.org\/10.2337\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":25,"title":["CTRP13 Preserves Endothelial Function by Targeting GTP Cyclohydrolase 1 in Diabetes"],"prefix":"10.2337","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7185-2671","authenticated-orcid":false,"given":"Cheng","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuelin","family":"Chao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minglu","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donghong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2019,11,1]]},"reference":[{"key":"2019122019451296000_69.1.99.1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.10.1134"},{"key":"2019122019451296000_69.1.99.2","doi-asserted-by":"crossref","first-page":"653789","DOI":"10.1155\/2013\/653789","article-title":"Impact of diabetes on cardiovascular disease: an update","volume":"2013","author":"Matheus","year":"2013","journal-title":"Int J Hypertens"},{"key":"2019122019451296000_69.1.99.3","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-s239"},{"key":"2019122019451296000_69.1.99.4","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2015.30.9.1213"},{"key":"2019122019451296000_69.1.99.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2013.08.006"},{"key":"2019122019451296000_69.1.99.6","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.1.25"},{"key":"2019122019451296000_69.1.99.7","doi-asserted-by":"crossref","first-page":"1935S","DOI":"10.1093\/jn\/136.7.1935S","article-title":"Adipose tissue and adipokines--energy regulation from the human perspective","volume":"136","author":"Trayhurn","year":"2006","journal-title":"J Nutr"},{"key":"2019122019451296000_69.1.99.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2012.12.029"},{"key":"2019122019451296000_69.1.99.9","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/648239"},{"key":"2019122019451296000_69.1.99.10","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/ijo.2009.205","article-title":"Adiponectin directly improves endothelial dysfunction in obese rats through the AMPK-eNOS pathway","volume":"34","author":"Deng","year":"2010","journal-title":"Int J Obes"},{"key":"2019122019451296000_69.1.99.11","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.112.251140"},{"key":"2019122019451296000_69.1.99.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2004.12.046"},{"key":"2019122019451296000_69.1.99.13","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00431.2009"},{"key":"2019122019451296000_69.1.99.14","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-013-9255-7"},{"key":"2019122019451296000_69.1.99.15","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.201087"},{"key":"2019122019451296000_69.1.99.16","doi-asserted-by":"crossref","first-page":"9627","DOI":"10.1096\/fj.201900293RRR","article-title":"CTRP13 attenuates vascular calcification by regulating Runx2","volume":"33","author":"Li","year":"2019","journal-title":"FASEB J"},{"key":"2019122019451296000_69.1.99.17","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1096\/fj.201801267RR","article-title":"CTRP13 inhibits atherosclerosis via autophagy-lysosome-dependent degradation of CD36","volume":"33","author":"Wang","year":"2019","journal-title":"FASEB J"},{"key":"2019122019451296000_69.1.99.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.05.009"},{"key":"2019122019451296000_69.1.99.19","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.109.212530"},{"key":"2019122019451296000_69.1.99.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.01.005"},{"key":"2019122019451296000_69.1.99.21","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1038\/s41467-019-09174-1","article-title":"Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2","volume":"10","author":"Wang","year":"2019","journal-title":"Nat Commun"},{"key":"2019122019451296000_69.1.99.22","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00160-13"},{"key":"2019122019451296000_69.1.99.23","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.602532"},{"key":"2019122019451296000_69.1.99.24","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00124.2004"},{"key":"2019122019451296000_69.1.99.25","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2013.5566"},{"key":"2019122019451296000_69.1.99.26","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M809295200"},{"key":"2019122019451296000_69.1.99.27","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2011.03.010"},{"key":"2019122019451296000_69.1.99.28","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M807959200"},{"key":"2019122019451296000_69.1.99.29","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2007.04.018"},{"key":"2019122019451296000_69.1.99.30","doi-asserted-by":"publisher","DOI":"10.1210\/me.14.12.1962"},{"key":"2019122019451296000_69.1.99.31","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.03089"},{"key":"2019122019451296000_69.1.99.32","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13728"},{"key":"2019122019451296000_69.1.99.33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.12.062"},{"key":"2019122019451296000_69.1.99.34","doi-asserted-by":"publisher","DOI":"10.2337\/db13-0751"},{"key":"2019122019451296000_69.1.99.35","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.017949"},{"key":"2019122019451296000_69.1.99.36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.10.039"},{"key":"2019122019451296000_69.1.99.37","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000118682.58708.78"},{"key":"2019122019451296000_69.1.99.38","doi-asserted-by":"crossref","first-page":"728494","DOI":"10.1155\/2015\/728494","article-title":"Restoration of endothelial function in Ppar\u03b1 (-\/-) mice by tempol","volume":"2015","author":"Silswal","year":"2015","journal-title":"PPAR Res"},{"key":"2019122019451296000_69.1.99.39","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.21.12481"}],"container-title":["Diabetes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/diabetes.diabetesjournals.org\/syndication\/doi\/10.2337\/db19-0635","content-type":"unspecified","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.2337\/db19-0635","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T04:56:32Z","timestamp":1590123392000},"score":1,"resource":{"primary":{"URL":"http:\/\/diabetes.diabetesjournals.org\/lookup\/doi\/10.2337\/db19-0635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,1]]},"references-count":39,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,12,20]]},"published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.2337\/db19-0635"],"URL":"https:\/\/doi.org\/10.2337\/db19-0635","relation":{},"ISSN":["0012-1797","1939-327X"],"issn-type":[{"value":"0012-1797","type":"print"},{"value":"1939-327X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,1]]}}}