{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T16:02:26Z","timestamp":1790524946549,"version":"4.1.0"},"reference-count":61,"publisher":"American Diabetes Association","issue":"12","license":[{"start":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T00:00:00Z","timestamp":1634860800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.diabetesjournals.org\/content\/license"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,12,1]]},"abstract":"<jats:p>The coronavirus disease 2019 (COVID-19) global pandemic continues to spread worldwide with approximately 216 million confirmed cases and 4.49 million deaths to date. Intensive efforts are ongoing to combat this disease by suppressing viral transmission, understanding its pathogenesis, developing vaccination strategies, and identifying effective therapeutic targets. Individuals with preexisting diabetes also show higher incidence of COVID-19 illness and poorer prognosis upon infection. Likewise, an increased frequency of diabetes onset and diabetes complications has been reported in patients following COVID-19 diagnosis. COVID-19 may elevate the risk of hyperglycemia and other complications in patients with and without prior diabetes history. It is unclear whether the virus induces type 1 or type 2 diabetes or instead causes a novel atypical form of diabetes. Moreover, it remains unknown if recovering COVID-19 patients exhibit a higher risk of developing new-onset diabetes or its complications going forward. The aim of this review is to summarize what is currently known about the epidemiology and mechanisms of this bidirectional relationship between COVID-19 and diabetes. We highlight major challenges that hinder the study of COVID-19\u2013induced new-onset of diabetes and propose a potential framework for overcoming these obstacles. We also review state-of-the-art wearables and microsampling technologies that can further study diabetes management and progression in new-onset diabetes cases. We conclude by outlining current research initiatives investigating the bidirectional relationship between COVID-19 and diabetes, some with emphasis on wearable technology.<\/jats:p>","DOI":"10.2337\/dbi21-0029","type":"journal-article","created":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T15:35:24Z","timestamp":1634916924000},"page":"2733-2744","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":73,"title":["COVID-19\u2013Induced New-Onset Diabetes: Trends and Technologies"],"prefix":"10.2337","volume":"70","author":[{"given":"Ahmed A.","family":"Metwally","sequence":"first","affiliation":[{"name":"Department of Genetics, Stanford University, Stanford, CA"},{"name":"Illumina Artificial Intelligence Laboratory, Illumina Inc., San Diego, CA"},{"name":"Systems and Biomedical Engineering Department, Faculty of Engineering, Cairo University, Giza, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pranav","family":"Mehta","sequence":"additional","affiliation":[{"name":"Rice University, Houston, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian S.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Genetics, Stanford University, Stanford, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anvith","family":"Nagarjuna","sequence":"additional","affiliation":[{"name":"Department of Genetics, Stanford University, Stanford, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0784-7987","authenticated-orcid":false,"given":"Michael P.","family":"Snyder","sequence":"additional","affiliation":[{"name":"Department of Genetics, Stanford University, Stanford, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2021,10,22]]},"reference":[{"key":"2022031310174144600_B1","unstructured":"World Health Organization\n          . 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