{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T15:01:06Z","timestamp":1791126066887,"version":"4.1.0"},"reference-count":43,"publisher":"American Diabetes Association","issue":"7","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2007,7,1]]},"abstract":"<jats:p>OBJECTIVE\u2014 The aim of this study was to examine the relationship between type 1 and type 2 diabetes and risk of stroke subtypes in women.<\/jats:p>\n               <jats:p>RESEARCH DESIGN AND METHODS\u2014 We followed 116,316 women aged 30\u201355 years in 1976 through 2002 for incidence of stroke. At baseline and through biennial follow-up, women were asked about their history and treatment of diabetes and other potential risk factors for stroke.<\/jats:p>\n               <jats:p>RESULTS\u2014 During 2.87 million person-years of follow-up, 3,463 incident strokes occurred. In multivariate analyses, the incidence of total stroke was fourfold higher in women with type 1 diabetes (relative risk [RR] 4.7 [95% CI 3.3\u20136.6]) and twofold higher among women with type 2 diabetes (1.8 [1.7\u20132.0]) than for nondiabetic women. The multivariate RR of ischemic stroke was increased sixfold (6.3 [4.0\u20139.8]) in type 1 diabetes and twofold (2.3 [2.0\u20132.6]) in type 2 diabetes. Risks for large-artery infarction and lacunar stroke were similar. Type 1 diabetes was also significantly associated with the risk of hemorrhagic stroke (3.8 [1.2\u201311.8]), but type 2 diabetes was not (1.0 [0.7\u20131.4]).<\/jats:p>\n               <jats:p>CONCLUSIONS\u2014 Both type 1 and type 2 diabetes are associated with substantially increased risks of total and most subtypes of stroke.<\/jats:p>","DOI":"10.2337\/dc06-2363","type":"journal-article","created":{"date-parts":[[2007,6,27]],"date-time":"2007-06-27T17:28:10Z","timestamp":1182965290000},"page":"1730-1735","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":178,"title":["Prospective Study of Type 1 and Type 2 Diabetes and Risk of Stroke Subtypes"],"prefix":"10.2337","volume":"30","author":[{"given":"Mohsen","family":"Janghorbani","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran"},{"name":"Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank B.","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts"},{"name":"Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter C.","family":"Willett","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts"},{"name":"Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts"},{"name":"Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tricia Y.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joann E.","family":"Manson","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts"},{"name":"Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"},{"name":"Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giancarlo","family":"Logroscino","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn M.","family":"Rexrode","sequence":"additional","affiliation":[{"name":"Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"},{"name":"Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","reference":[{"key":"2022031217382523100_R1","doi-asserted-by":"crossref","unstructured":"Jorgensen H, Nakayama H, Raaschou HO, Olsen TS: Stroke in patients with diabetes: the Copenhagen Stroke Study. 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