{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T23:57:34Z","timestamp":1789516654675,"version":"build-2803163510"},"reference-count":9,"publisher":"American Diabetes Association","issue":"5","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2008,5,1]]},"abstract":"<jats:p>OBJECTIVES\u2014To measure left ventricular mass (LVM), left ventricular volumes, and left ventricular function (LVF) in a cohort of type 1 diabetic patients and to correlate measures of imaging to NH2-terminal pro-brain natriuretic peptide (NT-proBNP).<\/jats:p>\n               <jats:p>RESEARCH DESIGN AND METHODS\u2014In a cross-sectional study, all patients with type 1 diabetes underwent cardiovascular magnetic resonance imaging. We included 63 patients with diabetic nephropathy and 73 patients with normoalbuminuria.<\/jats:p>\n               <jats:p>RESULTS\u2014All patients had normal global LVF. LVM was increased in patients with diabetic nephropathy compared with patients with persistent normoalbuminuria. Patients with nephropathy had smaller left ventricular volumes and increased levels of NT-proBNP. Linear regression analysis in patients with diabetic nephropathy showed that NT-proBNP and creatinine were associated with LVM.<\/jats:p>\n               <jats:p>CONCLUSIONS\u2014Increased LVM is identified in asymptomatic type 1 diabetic patients with nephropathy compared with normoalbuminuric patients. Elevated levels of NT-proBNP were associated with increased LVM, which are both markers of increased cardiovascular risk.<\/jats:p>","DOI":"10.2337\/dc07-1536","type":"journal-article","created":{"date-parts":[[2008,4,29]],"date-time":"2008-04-29T16:06:21Z","timestamp":1209485181000},"page":"968-970","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":6,"title":["Relation of Left Ventricular Function, Mass, and Volume to NT-proBNP in Type 1 Diabetic Patients"],"prefix":"10.2337","volume":"31","author":[{"given":"Anne Sofie","family":"Astrup","sequence":"first","affiliation":[{"name":"Steno Diabetes Center, Gentofte, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Yong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Skejby Hospital, Aarhus University Hospital, Aarhus, Denmark"},{"name":"MR-Center, Skejby Hospital, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Tarnow","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center, Gentofte, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rene\u0301 M.","family":"Botnar","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Technical University Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Simonsen","sequence":"additional","affiliation":[{"name":"MR-Center, Skejby Hospital, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lau","family":"Brix","sequence":"additional","affiliation":[{"name":"MR-Center, Skejby Hospital, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lotte","family":"Pietraszek","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center, Gentofte, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Riis","family":"Hansen","sequence":"additional","affiliation":[{"name":"Gentofte Hospital, Gentofte, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren J.","family":"Manning","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cardiovascular Division, and the Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Henrik","family":"Parving","sequence":"additional","affiliation":[{"name":"Department of Medical Endocrinology, Rigshospitalet, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","reference":[{"key":"2022031219413229400_R1","doi-asserted-by":"crossref","unstructured":"Astrup AS, Tarnow L, Rossing P, Pietraszek L, Hansen PR, Parving HH: Improved prognosis in type 1 diabetic patients with nephropathy: a prospective follow-up study. Kidney Int\u200868:1250\u20131257, 2005","DOI":"10.1111\/j.1523-1755.2005.00521.x"},{"key":"2022031219413229400_R2","doi-asserted-by":"crossref","unstructured":"Kim WY, Astrup AS, Stuber M, Tarnow L, Falk E, Botnar RM, Simonsen C, Pietraszek L, Hansen PR, Manning WJ, Andersen NT, Parving HH: Subclinical coronary and aortic atherosclerosis detected by magnetic resonance imaging in type 1 diabetes with and without diabetic nephropathy. Circulation\u2008115:228\u2013235, 2007","DOI":"10.1161\/CIRCULATIONAHA.106.633339"},{"key":"2022031219413229400_R3","doi-asserted-by":"crossref","unstructured":"Tarnow L, Hildebrandt P, Hansen BV, Borch-Johnsen K, Parving HH: Plasma N-terminal pro-brain natriuretic peptide as an independent predictor of mortality in diabetic nephropathy. 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