{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:35:46Z","timestamp":1788863746024,"version":"build-2803163510"},"reference-count":11,"publisher":"American Diabetes Association","issue":"8","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":4131,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2010,8,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>To determine whether short-term improvement in pancreas graft survival with simultaneous pancreas-kidney (SPK) transplants translated into improved long-term survival, then to examine the implications of that determination.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>We analyzed data for 14,311 diabetic patients who received a first SPK transplant between October 1987 and November 2007, using Kaplan-Meier analysis for graft survival rates and Cox regression analysis for year-of-transplant effect.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Overall, from 1995 to 2004, 5-year pancreas graft survival stayed about the same (70\u201371%). Limiting analysis to grafts that survived more than 1 year, 5-year survival from 1987 to 2004 ranged from 80 to 84%. With 1987\u20131989 as reference, the adjusted hazard ratio for graft failure by year of transplant increased to 1.49 (95% CI 0.97\u20132.30) in 2000\u20132004.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Long-term pancreas graft survival has remained unchanged despite the dramatic decreases in technical failures and early acute rejection rates that have contributed to prolonged SPK graft survival.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc09-2276","type":"journal-article","created":{"date-parts":[[2010,5,12]],"date-time":"2010-05-12T01:46:25Z","timestamp":1273628785000},"page":"1789-1791","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":32,"title":["Long-Term Pancreas Allograft Survival in Simultaneous Pancreas-Kidney Transplantation by Era"],"prefix":"10.2337","volume":"33","author":[{"given":"Kayo","family":"Waki","sequence":"first","affiliation":[{"name":"Terasaki Foundation Laboratory, Los Angeles, California;"},{"name":"Graduate School of Medicine, University of Tokyo, Department of Metabolic Diseases, Tokyo, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul I.","family":"Terasaki","sequence":"additional","affiliation":[{"name":"Terasaki Foundation Laboratory, Los Angeles, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kadowaki","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, University of Tokyo, Department of Metabolic Diseases, Tokyo, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2010,5,11]]},"reference":[{"key":"2022031302125520800_B1","unstructured":"United Network for Organ Sharing [Internet], 2010. Richmond, VA. Available from http:\/\/www.unos.org\/Data\/. Accessed 16 March 2010"},{"key":"2022031302125520800_B2","unstructured":"International Pancreas Transplant Registry: 2004 Annual Report [Internet], c2010. Minneapolis-St.Paul, MN, University of Minnesota. Available from http:\/\/www.iptr.umn.edu\/annual_reports\/2004_annual_report\/home.html. Accessed 16 March 16 2010"},{"key":"2022031302125520800_B3","first-page":"9","article-title":"An analysis of long-term survival from the OPTN\/UNOS Pancreas Transplant Registry","volume":"l","author":"Waki","year":"2007","journal-title":"Clin Transp"},{"key":"2022031302125520800_B4","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1016\/j.transproceed.2007.07.010","article-title":"Long-term results after pancreas transplantation","volume":"39","author":"Sutherland","year":"2007","journal-title":"Transplant Proc"},{"key":"2022031302125520800_B5","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1399-0012.2005.00378.x","article-title":"Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004","volume":"19","author":"Gruessner","year":"2005","journal-title":"Clin Transplant"},{"key":"2022031302125520800_B6","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1080\/00015458.2008.11680243","article-title":"The history of pancreas transplantation: past, present and future","volume":"108","author":"Squifflet","year":"2008","journal-title":"Acta Chir Belg"},{"key":"2022031302125520800_B7","first-page":"549","article-title":"Metabolic characterization of long-term successful pancreas transplants in type I diabetes","volume":"44","author":"Robertson","year":"1996","journal-title":"J Investig Med"},{"key":"2022031302125520800_B8","first-page":"1868","article-title":"Therapeutic controversy: Pancreas transplantation for type I diabetes","volume":"83","author":"Robertson","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"2022031302125520800_B9","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1097\/01.TP.0000147789.06043.A6","article-title":"Long-term follow-up of 78 simultaneous pancreas-kidney transplants at a single-center institution in Europe","volume":"78","author":"Drognitz","year":"2004","journal-title":"Transplantation"},{"key":"2022031302125520800_B10","doi-asserted-by":"crossref","first-page":"845","DOI":"10.2215\/CJN.02250508","article-title":"Living donor kidney versus simultaneous pancreas-kidney transplant in type I diabetics: an analysis of the OPTN\/UNOS database","volume":"4","author":"Young","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"2022031302125520800_B11","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0140-6736(94)90880-X","article-title":"Pancreas and kidney\/pancreas transplants: experimental medicine or real improvement?","volume":"343","author":"Remuzzi","year":"1994","journal-title":"Lancet"}],"container-title":["Diabetes Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/33\/8\/1789\/607069\/zdc00810001789.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/33\/8\/1789\/607069\/zdc00810001789.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,13]],"date-time":"2022-03-13T06:21:08Z","timestamp":1647152468000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/care\/article\/33\/8\/1789\/39191\/Long-Term-Pancreas-Allograft-Survival-in"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,11]]},"references-count":11,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2010,5,11]]},"published-print":{"date-parts":[[2010,8,1]]}},"URL":"https:\/\/doi.org\/10.2337\/dc09-2276","relation":{},"ISSN":["0149-5992","1935-5548"],"issn-type":[{"value":"0149-5992","type":"print"},{"value":"1935-5548","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,11]]}}}