{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T11:45:22Z","timestamp":1786621522750,"version":"build-2736575974"},"reference-count":24,"publisher":"American Diabetes Association","issue":"2","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":3877,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,2,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>Many studies have reported that periodontal disease is associated with diabetes, but its relation with impaired fasting glucose (IFG) has been understudied. This study investigated the relationship between chronic periodontitis, IFG, and diabetes in the U.S. population.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>Participants in the National Health and Nutrition Examination Survey III, aged \u226520 years, who received periodontal examinations and provided blood samples (n = 12,254) were grouped into quintiles of mean clinical attachment loss (CAL) and pocket depth, with the lowest category being the reference. Plasma fasting glucose was categorized into three groups (normal, &amp;lt;100 mg\/dL; IFG, \u2265100 but &amp;lt;126 mg\/dL; and diabetic, \u2265126 mg\/dL). Sociodemographic factors and other potential risk factors were obtained by interview or examination. SAS 9.1 was used for statistical analysis accounting for the complex weighted sampling.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Participants in the top quintile category of CAL had higher prevalence odds of IFG (odds ratio [OR] 1.55 [95% CI 1.16\u20132.07]) and diabetes (4.77 [2.69\u20138.46]) after adjustment for related confounders, compared with those in the bottom quintile. The highest quintile of pocket depth was positively associated with IFG (1.39 [1.00\u20131.92]) and diabetes (1.63 [1.10\u20132.42]) compared with the lowest quintile. ORs for CAL increased from the lowest to the highest quintile (P value test for trend &amp;lt;0.01) for all outcomes. The ORs for pocket depth also tended to rise across quintiles.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Chronic periodontitis measured by CAL and pocket depth was positively associated in a linear relation with IFG and diabetes in U.S. adults.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc10-1354","type":"journal-article","created":{"date-parts":[[2011,1,8]],"date-time":"2011-01-08T03:05:09Z","timestamp":1294455909000},"page":"381-386","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":89,"title":["Association Between Periodontitis and Impaired Fasting Glucose and Diabetes"],"prefix":"10.2337","volume":"34","author":[{"given":"Youn-Hee","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina"},{"name":"Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, Daegu, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert E.","family":"McKeown","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth J.","family":"Mayer-Davis","sequence":"additional","affiliation":[{"name":"Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela D.","family":"Liese","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina"},{"name":"Center for Research in Nutrition and Health Disparities, University of South Carolina, Columbia, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keun-Bae","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry, School of Dentistry, Kyungpook National University, Daegu, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anwar T.","family":"Merchant","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina"},{"name":"Center for Research in Nutrition and Health Disparities, University of South Carolina, Columbia, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2011,1,20]]},"reference":[{"key":"2022031302095887000_B1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1601-0825.2008.01442.x","article-title":"Periodontal 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