{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:17:37Z","timestamp":1789690657351,"version":"4.0.1"},"reference-count":15,"publisher":"American Diabetes Association","issue":"6","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":3400,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,6,1]]},"abstract":"<jats:sec>\n                  <jats:title\/>\n                  <jats:sec>\n                     <jats:title>OBJECTIVE<\/jats:title>\n                     <jats:p>To examine demographic, socioeconomic, and biological risk factors for all-cause, cardiovascular, and noncardiovascular mortality in patients with type 2 diabetes over 8 years and to construct mortality prediction equations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                     <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                     <jats:p>Beginning in 2000, survey and medical record information was obtained from 8,334 participants in Translating Research Into Action for Diabetes (TRIAD), a multicenter prospective observational study of diabetes care in managed care. The National Death Index was searched annually to obtain data on deaths over an 8-year follow-up period (2000\u20132007). Predictors examined included age, sex, race, education, income, smoking, age at diagnosis of diabetes, duration and treatment of diabetes, BMI, complications, comorbidities, and medication use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                     <jats:title>RESULTS<\/jats:title>\n                     <jats:p>There were 1,616 (19%) deaths over the 8-year period. In the most parsimonious equation, the predictors of all-cause mortality included older age, male sex, white race, lower income, smoking, insulin treatment, nephropathy, history of dyslipidemia, higher LDL cholesterol, angina\/myocardial infarction\/other coronary disease\/coronary angioplasty\/bypass, congestive heart failure, aspirin, \u03b2-blocker, and diuretic use, and higher Charlson Index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                     <jats:title>CONCLUSIONS<\/jats:title>\n                     <jats:p>Risk of death can be predicted in people with type 2 diabetes using simple demographic, socioeconomic, and biological risk factors with fair reliability. Such prediction equations are essential for computer simulation models of diabetes progression and may, with further validation, be useful for patient management.<\/jats:p>\n                  <\/jats:sec>\n               <\/jats:sec>","DOI":"10.2337\/dc11-2281","type":"journal-article","created":{"date-parts":[[2012,3,20]],"date-time":"2012-03-20T05:11:53Z","timestamp":1332220313000},"page":"1301-1309","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":114,"title":["Predictors of Mortality Over 8 Years in Type 2 Diabetic Patients"],"prefix":"10.2337","volume":"35","author":[{"given":"Laura N.","family":"McEwen","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Karter","sequence":"additional","affiliation":[{"name":"Kaiser Permanente, Division of Research, Oakland, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth E.","family":"Waitzfelder","sequence":"additional","affiliation":[{"name":"Kaiser Permanente, Center for Health Research, Honolulu, Hawaii"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse C.","family":"Crosson","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health, UMDNJ\u2013Robert Wood Johnson Medical School, Somerset, New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G.","family":"Marrero","sequence":"additional","affiliation":[{"name":"Indiana University Diabetes Translational Research Center, Indianapolis, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol M.","family":"Mangione","sequence":"additional","affiliation":[{"name":"University of California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William H.","family":"Herman","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan"},{"name":"Department of Epidemiology, University of Michigan, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2012,5,11]]},"reference":[{"key":"2022031302554521200_B1","unstructured":"National Center for Chronic Disease Prevention and Health Promotion. 2007 National Diabetes Fact Sheet [Internet] 2007. Available from http:\/\/www.cdc.gov\/diabetes\/pubs\/estimates07.htm. Accessed 3 December 2010"},{"key":"2022031302554521200_B2","unstructured":"National Center for Health Statistics. Leading Causes of Death [Internet], 2007. Available from http:\/\/www.cdc.gov\/nchs\/fastats\/lcod.htm. Accessed 3 December 2010"},{"key":"2022031302554521200_B3","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2337\/diacare.29.02.06.dc05-0998","article-title":"Diabetes reporting as a cause of death: results from the Translating Research Into Action for Diabetes (TRIAD) study","volume":"29","author":"McEwen","year":"2006","journal-title":"Diabetes Care"},{"key":"2022031302554521200_B4","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0895-4356(00)00303-6","article-title":"Recording of diabetes on death certificates. 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National Center for Health Statistics: National Death Index (NDI), NDI Plus Searches [Internet]. Available from http:\/\/www.cdc.gov\/nchs\/ndi.htm. 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