{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T23:00:19Z","timestamp":1704495619464},"reference-count":10,"publisher":"American Diabetes Association","issue":"3","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":3122,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,3,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>Electrocardiographic indices reflecting left ventricular hypertrophy are associated with incident diabetes in clinical populations at risk for coronary heart disease. We tested whether electrocardiographically determined left ventricular mass was positively associated with incident diabetes in a population sample.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>Coronary Artery Risk Development in Young Adults (CARDIA) study participants (n = 4,739) were followed from 1985\u20131986 to 2010\u20132011 for incident diabetes. Validated sex- and race-specific formulas were applied to standard electrocardiograms to determine left ventricular mass.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Over 25 years, 444 participants developed diabetes (9.4%). After adjustment for demographic, behavioral, and clinical covariates, participants in the highest quartile of left ventricular mass index (LVMI) were twice as likely to develop diabetes than participants in the lower three quartiles (hazard ratio 2.61 [95% CI 2.16\u20133.17]). Neither Cornell voltage nor Cornell voltage product was associated with incident diabetes in fully adjusted models.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Electrocardiographically determined LVMI may be a useful noninvasive marker for identifying adults at risk for diabetes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc12-1359","type":"journal-article","created":{"date-parts":[[2012,11,17]],"date-time":"2012-11-17T04:52:46Z","timestamp":1353127966000},"page":"645-647","update-policy":"http:\/\/dx.doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":5,"title":["Association of Electrocardiographically Determined Left Ventricular Mass With Incident Diabetes, 1985\u20131986 to 2010\u20132011"],"prefix":"10.2337","volume":"36","author":[{"given":"Mercedes R.","family":"Carnethon","sequence":"first","affiliation":[{"name":"Department of Preventive Medicine, Feinberg School of Medicine at Northwestern University, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyan","family":"Ning","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Feinberg School of Medicine at Northwestern University, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elsayed Z.","family":"Soliman","sequence":"additional","affiliation":[{"name":"Division of Public Health Sciences, Department of Epidemiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cora E.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela J.","family":"Schreiner","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Sidney","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Division of Research, Oakland, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald M.","family":"Lloyd-Jones","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Feinberg School of Medicine at Northwestern University, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","published-online":{"date-parts":[[2013,2,13]]},"reference":[{"key":"2022031302060823900_B1","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1161\/HYPERTENSIONAHA.107.096818","article-title":"In-treatment resolution or absence of electrocardiographic left ventricular hypertrophy is associated with decreased incidence of new-onset diabetes mellitus in hypertensive patients: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) Study","volume":"50","author":"Okin","year":"2007","journal-title":"Hypertension"},{"key":"2022031302060823900_B2","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S0140-6736(02)08089-3","article-title":"Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol","volume":"359","author":"Dahl\u00f6f","year":"2002","journal-title":"Lancet"},{"key":"2022031302060823900_B3","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/0895-4356(88)90080-7","article-title":"CARDIA: study design, recruitment, and some characteristics of the examined subjects","volume":"41","author":"Friedman","year":"1988","journal-title":"J Clin Epidemiol"},{"key":"2022031302060823900_B4","first-page":"385.e1","article-title":"Prevalence of electrocardiographic abnormalities in a middle-aged, biracial population: Coronary Artery Risk Development in Young Adults study","volume-title":"J Electrocardiol","year":"2010"},{"key":"2022031302060823900_B5","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1054\/jelc.2000.7667","article-title":"Race- and sex-specific ECG models for left ventricular mass in older populations. 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Coronary Artery Risk Development in Young Adults","volume":"144","author":"Folsom","year":"1996","journal-title":"Am J Epidemiol"},{"key":"2022031302060823900_B8","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1002\/sim.1802","article-title":"Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation","volume":"23","author":"Pencina","year":"2004","journal-title":"Stat Med"},{"key":"2022031302060823900_B9","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1161\/01.HYP.0000125726.92964.ab","article-title":"Adverse prognostic significance of new diabetes in treated hypertensive subjects","volume":"43","author":"Verdecchia","year":"2004","journal-title":"Hypertension"},{"key":"2022031302060823900_B10","first-page":"4284","article-title":"Relation among left ventricular mass, insulin resistance, and blood pressure in nonobese subjects","volume":"83","author":"Phillips","year":"1998","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Diabetes Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/36\/3\/645\/615562\/645.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/36\/3\/645\/615562\/645.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,13]],"date-time":"2022-03-13T06:13:51Z","timestamp":1647152031000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/care\/article\/36\/3\/645\/38062\/Association-of-Electrocardiographically-Determined"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,13]]},"references-count":10,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2013,2,13]]},"published-print":{"date-parts":[[2013,3,1]]}},"URL":"https:\/\/doi.org\/10.2337\/dc12-1359","relation":{},"ISSN":["0149-5992","1935-5548"],"issn-type":[{"value":"0149-5992","type":"print"},{"value":"1935-5548","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,13]]}}}