{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T06:29:22Z","timestamp":1782800962477,"version":"3.54.5"},"reference-count":40,"publisher":"American Diabetes Association","issue":"3","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":3122,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,3,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>To examine the association between self-reported physical activity (PA) and diabetes-related quantitative traits.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>The observational cohort was 1,152 Mexican American adults with dual-energy X-ray absorptiometry, oral and intravenous glucose tolerance tests, and self-reported dietary and PA questionnaires. PA was categorized into three mutually exclusive groups according to the U.S. Department of Health and Human Services PA guidelines for Americans: low (vigorous &amp;lt;75 min\/week and moderate &amp;lt;150 min\/week), moderate (vigorous \u226575 min\/week or moderate \u2265150 min\/week), and high (vigorous \u226575 min\/week and moderate \u2265150 min\/week). Trends in PA groups were tested for association with metabolic traits in a cross-sectional analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The participants\u2019 mean age was 35 years (range, 18\u201366 years), mean BMI was 29.6 kg\/m2, and 73% were female. Among them, 501 (43%), 448 (39%), and 203 (18%) were classified as having low, moderate, and high PA, respectively. After adjustment for age, a higher PA was significantly associated with lower 2-h glucose, fasting insulin, and 2-h insulin and greater \u03b2-cell function (P = 0.001, 0.0003, 0.0001, and 0.004, respectively). The association did not differ significantly by sex. Results were similar after further adjustment for age, sex, BMI, or percent body fat.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>An increasing level of PA is associated with a better glucose and insulin profile and enhanced \u03b2-cell function that is not explained by differences in BMI or percent body fat. Our results suggest that PA can be beneficial to \u03b2-cell function and glucose regulation independent of obesity.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc12-1485","type":"journal-article","created":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T03:02:08Z","timestamp":1354762928000},"page":"638-644","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":18,"title":["Self-Reported Physical Activity Is Associated With \u03b2-Cell Function in Mexican American Adults"],"prefix":"10.2337","volume":"36","author":[{"given":"Zhanghua","family":"Chen","sequence":"first","affiliation":[{"name":"Division of Biostatistics, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Helen","family":"Black","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation, 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