{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:52:50Z","timestamp":1789624370614,"version":"build-2803163510"},"reference-count":34,"publisher":"American Diabetes Association","issue":"10","license":[{"start":{"date-parts":[[2021,8,28]],"date-time":"2021-08-28T00:00:00Z","timestamp":1630108800000},"content-version":"vor","delay-in-days":2905,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,10,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>To describe the prevalence of physical function limitations among a nationally representative sample of adults with prediabetes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>We performed a cross-sectional analysis of 5,991 respondents \u226553 years of age from the 2006 wave of the Health and Retirement Study. All respondents self-reported physical function limitations and comorbidities (chronic diseases and geriatric conditions). Respondents with prediabetes reported no diabetes and had a measured glycosylated hemoglobin (HbA1c) of 5.7\u20136.4%. Descriptive analyses and logistic regressions were used to compare respondents with prediabetes versus diabetes (diabetes history or HbA1c \u22656.5%) or normoglycemia (no diabetes history and HbA1c &amp;lt;5.7%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Twenty-eight percent of respondents \u226553 years of age had prediabetes; 32% had mobility limitations (walking several blocks and\/or climbing a flight of stairs); 56% had lower-extremity limitations (getting up from a chair and\/or stooping, kneeling, or crouching); and 33% had upper-extremity limitations (pushing or pulling heavy objects and\/or lifting &amp;gt;10 lb). Respondents with diabetes had the highest prevalence of comorbidities and physical function limitations, followed by those with prediabetes, and then normoglycemia (P &amp;lt; 0.05). Compared with respondents with normoglycemia, respondents with prediabetes had a higher odds of having functional limitations that affected mobility (odds ratio [OR] 1.48), the lower extremities (OR 1.35), and the upper extremities (OR 1.37) (all P &amp;lt; 0.01). The higher odds of having lower-extremity limitations remained after adjusting for age, sex, and body mass index (OR 1.21, P &amp;lt; 0.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Comorbidities and physical function limitations are prevalent among middle-aged and older adults with prediabetes. Effective lifestyle interventions to prevent diabetes must accommodate physical function limitations.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc13-0412","type":"journal-article","created":{"date-parts":[[2013,6,12]],"date-time":"2013-06-12T01:10:55Z","timestamp":1370999455000},"page":"3076-3083","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":42,"title":["Physical Function Limitations Among Middle-Aged and Older Adults With Prediabetes"],"prefix":"10.2337","volume":"36","author":[{"given":"Pearl G.","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan"},{"name":"Veterans Affairs Ann Arbor Healthcare System, Geriatrics Research, Education and Clinical Center, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine T.","family":"Cigolle","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan"},{"name":"Veterans Affairs Ann Arbor Healthcare System, Geriatrics Research, Education and Clinical Center, Ann Arbor, Michigan"},{"name":"Department of Family Medicine, University of Michigan, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinkyung","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian","family":"Min","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan"},{"name":"Veterans Affairs Ann Arbor Healthcare System, Geriatrics Research, Education and Clinical Center, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Veterans Affairs Ann Arbor Healthcare System, Geriatrics Research, Education and Clinical Center, Ann Arbor, Michigan"},{"name":"Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline S.","family":"Blaum","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, New York University, New York, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William H.","family":"Herman","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Michigan, Ann Arbor, 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