{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:38:21Z","timestamp":1790091501835,"version":"4.0.1"},"reference-count":31,"publisher":"American Diabetes Association","issue":"11","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,11,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>Effective treatment algorithms are needed to guide diabetes care at hospital discharge in general medicine and surgery patients with type 2 diabetes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>This was a prospective, multicenter open-label study aimed to determine the safety and efficacy of a hospital discharge algorithm based on admission HbA1c. Patients with HbA1c &amp;lt;7% (53.0 mmol\/mol) were discharged on their preadmission diabetes therapy, HbA1c between 7 and 9% (53.0\u201374.9 mmol\/mol) were discharged on a preadmission regimen plus glargine at 50% of hospital daily dose, and HbA1c &amp;gt;9% were discharged on oral antidiabetes agents (OADs) plus glargine or basal bolus regimen at 80% of inpatient dose. The primary outcome was HbA1c concentration at 12 weeks after hospital discharge.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>A total of 224 patients were discharged on OAD (36%), combination of OAD and glargine (27%), basal bolus (24%), glargine alone (9%), and diet (4%). The admission HbA1c was 8.7 \u00b1 2.5% (71.6 mmol\/mol) and decreased to 7.3 \u00b1 1.5% (56 mmol\/mol) at 12 weeks of follow-up (P &amp;lt; 0.001). The change of HbA1c from baseline at 12 weeks after discharge was \u22120.1 \u00b1 0.6, \u22120.8 \u00b1 1.0, and \u22123.2 \u00b1 2.4 in patients with HbA1c &amp;lt;7%, 7\u20139%, and &amp;gt;9%, respectively (P &amp;lt; 0.001). Hypoglycemia (&amp;lt;70 mg\/dL) was reported in 22% of patients discharged on OAD only, 30% on OAD plus glargine, 44% on basal bolus, and 25% on glargine alone and was similar in patients with admission HbA1c \u22647% (26%) compared with those with HbA1c &amp;gt;7% (31%, P = 0.54).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Measurement of HbA1c on admission is beneficial in tailoring treatment regimens at discharge in general medicine and surgery patients with type 2 diabetes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc14-0479","type":"journal-article","created":{"date-parts":[[2014,8,29]],"date-time":"2014-08-29T05:38:44Z","timestamp":1409290724000},"page":"2934-2939","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":109,"title":["Hospital Discharge Algorithm Based on Admission HbA1c for the Management of Patients With Type 2 Diabetes"],"prefix":"10.2337","volume":"37","author":[{"given":"Guillermo E.","family":"Umpierrez","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Emory University, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Reyes","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Emory University, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn","family":"Smiley","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Emory University, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathie","family":"Hermayer","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Medical University of South Carolina, Charleston, SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amna","family":"Khan","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Tulane Medical Center, New Orleans, LA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darin E.","family":"Olson","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Emory University, Atlanta, GA"},{"name":"Atlanta Veterans Affairs Medical Center, Decatur, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Pasquel","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Emory University, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sol","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Emory University, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Newton","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Emory University, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Limin","family":"Peng","sequence":"additional","affiliation":[{"name":"Rollins School of Public Health, Emory University, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, Tulane Medical Center, New Orleans, LA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2014,10,10]]},"reference":[{"key":"2022031220273990800_B1","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.2337\/diacare.26.5.1421","article-title":"Multiple hospitalizations for patients with diabetes","volume":"26","author":"Jiang","year":"2003","journal-title":"Diabetes Care"},{"key":"2022031220273990800_B2","unstructured":"Fraze TK, Jiang HJ, Burgess J. 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