{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T19:13:27Z","timestamp":1790795607893,"version":"4.1.0"},"reference-count":25,"publisher":"American Diabetes Association","issue":"1","license":[{"start":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T00:00:00Z","timestamp":1545264000000},"content-version":"vor","delay-in-days":31,"URL":"http:\/\/www.diabetesjournals.org\/content\/license"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021728","name":"Bundy Academy","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100021728","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Folksam Research Foundation"},{"DOI":"10.13039\/100018870","name":"Swedish Heart and Lung Association","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100018870","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Anna Lisa and Sven Erik Lundgren\u2019s Foundation"},{"name":"Hulda and E Conrad Mossfelt\u2019s Foundation"},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["T32HL098048"],"award-info":[{"award-number":["T32HL098048"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["F31HL131222"],"award-info":[{"award-number":["F31HL131222"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UM1 CA176726"],"award-info":[{"award-number":["UM1 CA176726"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,1,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>To study the extent to which BMI after pregnancy adds to the elevated risk of postpregnancy type 2 diabetes in women with a history of hypertensive disorders of pregnancy (HDP) (preeclampsia or gestational hypertension).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>We used data from the Nurses\u2019 Health Study II, a prospective cohort study. In women aged 45\u201354 years without prior gestational diabetes mellitus, we investigated the interaction between BMI and HDP history on the risk of type 2 diabetes. For clinical and public health relevance, we focused on additive interaction. The main outcome measure was the relative excess risk due to interaction calculated from multivariable Cox proportional hazards models using normal weight as the reference group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>In total, 6,563 (11.7%) of 56,159 participants had a history of HDP and 1,341 women developed type 2 diabetes during 436,333 person-years. BMI was a strong risk factor for type 2 diabetes regardless of HDP history. However, there was evidence of an additive interaction between BMI and HDP for the risk of type 2 diabetes (P = 0.004). The attributable proportion of risk due to the interaction ranged from 0.12 (95% CI \u22120.22, 0.46) in women who were overweight to 0.36 (95% CI 0.13, 0.59) in women with obesity class I.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Maintaining a healthy weight may be of even greater importance in women with a history of HDP, compared with other women with a history of only normotensive pregnancies, to reduce midlife risk of type 2 diabetes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc18-1532","type":"journal-article","created":{"date-parts":[[2018,11,19]],"date-time":"2018-11-19T16:25:20Z","timestamp":1542644720000},"page":"44-49","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":9,"title":["Postpregnancy BMI in the Progression From Hypertensive Disorders of Pregnancy to Type 2 Diabetes"],"prefix":"10.2337","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7445-7212","authenticated-orcid":false,"given":"Simon","family":"Timpka","sequence":"first","affiliation":[{"name":"Connors Center for Women\u2019s Health and Gender Biology, Division of Women\u2019s Health, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, MA"},{"name":"Harvard Medical School, Boston, MA"},{"name":"Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences Malm\u00f6, Lund University, Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer J.","family":"Stuart","sequence":"additional","affiliation":[{"name":"Connors Center for Women\u2019s Health and Gender Biology, Division of Women\u2019s Health, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, MA"},{"name":"Harvard Medical School, Boston, MA"},{"name":"Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren J.","family":"Tanz","sequence":"additional","affiliation":[{"name":"Connors Center for Women\u2019s Health and Gender Biology, Division of Women\u2019s Health, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, MA"},{"name":"Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank B.","family":"Hu","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Boston, MA"},{"name":"Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA"},{"name":"Channing Division of Network Medicine, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0520-7604","authenticated-orcid":false,"given":"Paul W.","family":"Franks","sequence":"additional","affiliation":[{"name":"Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences Malm\u00f6, Lund University, Malm\u00f6, Sweden"},{"name":"Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet W.","family":"Rich-Edwards","sequence":"additional","affiliation":[{"name":"Connors Center for Women\u2019s Health and Gender Biology, Division of Women\u2019s Health, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, MA"},{"name":"Harvard Medical School, Boston, MA"},{"name":"Department of Epidemiology, Harvard T.H. 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