{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T09:21:17Z","timestamp":1792401677112,"version":"4.4.0"},"reference-count":44,"publisher":"American Diabetes Association","issue":"3","license":[{"start":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T00:00:00Z","timestamp":1613692800000},"content-version":"vor","delay-in-days":42,"URL":"https:\/\/www.diabetesjournals.org\/content\/license"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","award":["T32 HL007024"],"award-info":[{"award-number":["T32 HL007024"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K24 DK106414"],"award-info":[{"award-number":["K24 DK106414"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,3,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>To assess the prevalence of and trends in complications among U.S. adults with newly diagnosed diabetes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>We included 1,486 nonpregnant adults (aged \u226520 years) with newly diagnosed diabetes (diagnosed within the past 2 years) from the 1988\u20131994 and 1999\u20132018 National Health and Nutrition Examination Survey. We estimated trends in albuminuria (albumin-to-creatinine ratio \u226530 mg\/g), reduced estimated glomerular filtration rate (eGFR &amp;lt;60 mL\/min\/1.73 m2), retinopathy (any retinal microaneurysms or blot hemorrhages), and self-reported cardiovascular disease (history of congestive heart failure, heart attack, or stroke).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>From 1988\u20131994 to 2011\u20132018, there was a significant decrease in the prevalence of albuminuria (38.9 to 18.7%, P for trend &amp;lt;0.001) but no change in the prevalence of reduced eGFR (7.5 to 9.9%, P for trend = 0.30), retinopathy (1988\u20131994 to 1999\u20132008 only; 13.2 to 12.1%, P for trend = 0.86), or self-reported cardiovascular disease (19.0 to 16.5%, P for trend = 0.64). There were improvements in glycemic, blood pressure, and lipid control in the population, and these partially explained the decline in albuminuria. Complications were more common at the time of diabetes diagnosis for adults who were older, lower income, less educated, and obese.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Over the past three decades, there have been encouraging reductions in albuminuria and risk factor control in adults with newly diagnosed diabetes. However, the overall burden of complications around the time of the diagnosis remains high.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc20-2304","type":"journal-article","created":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T23:58:06Z","timestamp":1610150286000},"page":"699-706","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":56,"title":["Thirty-Year Trends in Complications in U.S. Adults With Newly Diagnosed Type 2 Diabetes"],"prefix":"10.2337","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2849-1780","authenticated-orcid":false,"given":"Michael","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Epidemiology and the Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6923-7151","authenticated-orcid":false,"given":"Elizabeth","family":"Selvin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and the Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2021,1,8]]},"reference":[{"key":"2022031309511157500_B1","doi-asserted-by":"crossref","first-page":"815","DOI":"10.2337\/diacare.15.7.815","article-title":"Onset of NIDDM occurs at least 4-7 yr before clinical diagnosis","volume":"15","author":"Harris","year":"1992","journal-title":"Diabetes Care"},{"key":"2022031309511157500_B2","doi-asserted-by":"crossref","first-page":"769","DOI":"10.7326\/M17-1272","article-title":"Identifying trends in undiagnosed diabetes in U.S. adults by using a confirmatory definition: a cross-sectional study","volume":"167","author":"Selvin","year":"2017","journal-title":"Ann Intern Med"},{"key":"2022031309511157500_B3","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.2337\/diacare.23.10.1563","article-title":"Screening for type 2 diabetes","volume":"23","author":"Engelgau","year":"2000","journal-title":"Diabetes Care"},{"key":"2022031309511157500_B4","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.2337\/dc16-2442","article-title":"Declines in the incidence of diabetes in the U.S.\u2014real progress or artifact","volume":"40","author":"Selvin","year":"2017","journal-title":"Diabetes Care"},{"key":"2022031309511157500_B5","doi-asserted-by":"crossref","first-page":"212","DOI":"10.7326\/0003-4819-138-3-200302040-00014","article-title":"Screening for type 2 diabetes mellitus in adults: recommendations and rationale","volume":"138","author":"U.S. Preventive Services Task Force","year":"2003","journal-title":"Ann Intern Med"},{"key":"2022031309511157500_B6","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.2337\/diacare.20.7.1183","article-title":"Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. 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