{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T17:09:23Z","timestamp":1782493763302,"version":"3.54.5"},"reference-count":31,"publisher":"American Diabetes Association","issue":"12","license":[{"start":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T00:00:00Z","timestamp":1633305600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.diabetesjournals.org\/content\/license"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,12,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>To examine short-term mortality and cause of death among youth and young adults (YYAs) with youth-onset diabetes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>We included 19,717 YYAs newly diagnosed with diabetes before 20 years of age from 1 January 2002 to 31 December 2015 enrolled in the SEARCH for Diabetes in Youth Study. Of these, 14,721 had type 1; 4,141 type 2; and 551 secondary and 304 other\/unknown diabetes type. Cases were linked with the National Death Index through 31 December 2017. We calculated standardized mortality ratios (SMRs) and 95% CIs based on age, sex, and race\/ethnicity for state and county population areas and examined underlying causes of death.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>During 170,148 person-years (PY) (median follow-up 8.5 years), 283 individuals died: 133 with type 1 (103.0\/100,000 PY), 55 with type 2 (161.5\/100,000 PY), 87 with secondary (1,952\/100,000 PY), and 8 with other\/unknown diabetes type (312.3\/100,000 PY). SMRs (95% CI) for the first three groups were 1.5 (1.2\u20131.8), 2.3 (1.7\u20133.0), and 28.0 (22.4\u201334.6), respectively. Diabetes was the underlying cause of death for 42.1%, 9.1%, and 4.6% of deaths, respectively. The SMR was greater for type 2 than for type 1 diabetes (P &amp;lt; 0.001). SMRs were significantly higher for individuals with type 1 diabetes who were &amp;lt;20 years of age, non-Hispanic White and Hispanic, and female and for individuals with type 2 diabetes who were &amp;lt;25 years of age, from all race\/ethnic minority groups, and from both sexes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Excess mortality was observed among YYAs for each type of diabetes with differences in risk associated with diabetes type, age, race\/ethnicity, and sex. The root causes of excess mortality among YYAs with diabetes merit further study.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc21-0728","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T18:21:52Z","timestamp":1633371712000},"page":"2691-2698","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":24,"title":["Demographic Correlates of Short-Term Mortality Among Youth and Young Adults With Youth-Onset Diabetes Diagnosed From 2002 to 2015: The SEARCH for Diabetes in Youth Study"],"prefix":"10.2337","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2480-8480","authenticated-orcid":false,"given":"Jean M.","family":"Lawrence","sequence":"first","affiliation":[{"name":"Division of Epidemiologic Research, Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA"},{"name":"Division of Diabetes, Endocrinology, and Metabolic Diseases, National 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