{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:53:50Z","timestamp":1790636030970,"version":"4.1.0"},"reference-count":20,"publisher":"American Diabetes Association","issue":"6","license":[{"start":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T00:00:00Z","timestamp":1680220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.diabetesjournals.org\/journals\/pages\/license"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["1UC4DK108612-01"],"award-info":[{"award-number":["1UC4DK108612-01"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Beta Bionics, Inc"},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Eli Lilly"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,6,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>We evaluated the performance of the iLet bionic pancreas (BP) in non-Hispanic White individuals (here referred to as \u201cWhites\u201d) and in Black, Hispanic, and other individuals (here collectively referred to as \u201cMinorities\u201d).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>A multicenter, randomized controlled trial evaluated glycemic management with the BP versus standard of care (SC) in 161 adult and 165 pediatric participants with type 1 diabetes over 13 weeks.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>In Whites (n = 240), the mean baseline-adjusted difference in 13-week HbA1c between the BP and SC groups was \u22120.45% (95% CI \u22120.61 to \u22120.29 [\u22124.9 mmol\/mol; \u22126.6 to \u22123.1]; P &amp;lt; 0.001), while this difference among Minorities (n = 84) was \u22120.53% (\u22120.83 to \u22120.24 [\u22126.0 mmol\/mol; \u22129.2 to \u22122.8]; P &amp;lt; 0.001). In Whites, the mean baseline-adjusted difference in time in range between the BP and SC groups was 10% (95% CI 7\u201312; P &amp;lt; 0.001) and in Minorities was 14% (10\u201318; P &amp;lt; 0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The BP improves glycemic control in both Whites and Minorities and offers promise in decreasing health care disparities.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc22-1478","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T17:08:38Z","timestamp":1680282518000},"page":"1185-1190","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":10,"title":["The Insulin-Only Bionic Pancreas Improves Glycemic Control in Non-Hispanic White and Minority Adults and Children With Type 1 Diabetes"],"prefix":"10.2337","volume":"46","author":[{"given":"Luz E.","family":"Castellanos","sequence":"first","affiliation":[{"name":"1Massachusetts General Hospital, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8423-5891","authenticated-orcid":false,"given":"Steven J.","family":"Russell","sequence":"additional","affiliation":[{"name":"2Beta Bionics, Concord, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward R.","family":"Damiano","sequence":"additional","affiliation":[{"name":"2Beta Bionics, Concord, MA"},{"name":"3Boston University, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy W.","family":"Beck","sequence":"additional","affiliation":[{"name":"4Jaeb Center for Health Research, Tampa, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viral N.","family":"Shah","sequence":"additional","affiliation":[{"name":"5Barbara Davis Center for Diabetes, University of Colorado, Aurora, CO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Bailey","sequence":"additional","affiliation":[{"name":"4Jaeb Center for Health Research, Tampa, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3688-578X","authenticated-orcid":false,"given":"Peter","family":"Calhoun","sequence":"additional","affiliation":[{"name":"4Jaeb Center for Health Research, Tampa, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisha","family":"Bird","sequence":"additional","affiliation":[{"name":"6Nemours Children\u2019s Health, Jacksonville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1175-3852","authenticated-orcid":false,"given":"Nelly","family":"Mauras","sequence":"additional","affiliation":[{"name":"6Nemours Children\u2019s Health, Jacksonville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Bionic Pancreas Research Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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