{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T22:00:25Z","timestamp":1791669625485,"version":"4.3.4"},"reference-count":42,"publisher":"American Diabetes Association","issue":"1","license":[{"start":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T00:00:00Z","timestamp":1698969600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.diabetesjournals.org\/journals\/pages\/license"}],"funder":[{"DOI":"10.13039\/100007028","name":"Leona M. and Harry B. Helmsley Charitable Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007028","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>Data from the Type 1 Diabetes Exercise Initiative Pediatric (T1DEXIP) study were evaluated to understand glucose changes during activity and identify factors that may influence changes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>In this real-world observational study, adolescents with type 1 diabetes self-reported physical activity, food intake, and insulin dosing (multiple-daily injection users) using a smartphone application. Heart rate and continuous glucose monitoring data were collected, as well as pump data downloads.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Two hundred fifty-one adolescents (age 14 \u00b1 2 years [mean \u00b1 SD]; HbA1c 7.1 \u00b1 1.3% [54 \u00b1 14.2 mmol\/mol]; 42% female) logged 3,738 activities over \u223c10 days of observation. Preactivity glucose was 163 \u00b1 66 mg\/dL (9.1 \u00b1 3.7 mmol\/L), dropping to 148 \u00b1 66 mg\/dL (8.2 \u00b1 3.7 mmol\/L) by end of activity; median duration of activity was 40 min (20, 75 [interquartile range]) with a mean and peak heart rate of 109 \u00b1 16 bpm and 130 \u00b1 21 bpm. Drops in glucose were greater in those with lower baseline HbA1c levels (P = 0.002), shorter disease duration (P = 0.02), less hypoglycemia fear (P = 0.04), and a lower BMI (P = 0.05). Event-level predictors of greater drops in glucose included self-classified \u201cnoncompetitive\u201d activities, insulin on board &amp;gt;0.05 units\/kg body mass, glucose already dropping prior to the activity, preactivity glucose &amp;gt;150 mg\/dL (&amp;gt;8.3 mmol\/L) and time 70\u2013180 mg\/dL &amp;gt;70% in the 24 h before the activity (all P &amp;lt; 0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Participant-level and activity event-level factors can help predict the magnitude of drop in glucose during real-world physical activity in youth with type 1 diabetes. A better appreciation of these factors may improve decision support tools and self-management strategies to reduce activity-induced dysglycemia in active adolescents living with the disease.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/dc23-1548","type":"journal-article","created":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T17:51:13Z","timestamp":1699033873000},"page":"132-139","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":44,"title":["The Acute Effects of Real-World Physical Activity on Glycemia in Adolescents With Type 1 Diabetes: The Type 1 Diabetes Exercise Initiative Pediatric (T1DEXIP) Study"],"prefix":"10.2337","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6556-7559","authenticated-orcid":false,"given":"Michael C.","family":"Riddell","sequence":"first","affiliation":[{"name":"1School of Kinesiology and Health Science, Muscle Health Research Centre, York University, Toronto, 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