{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T11:07:28Z","timestamp":1791630448896,"version":"4.3.4"},"reference-count":28,"publisher":"American Diabetes Association","issue":"2","license":[{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.diabetesjournals.org\/journals\/pages\/license"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To assess differences in time in range (TIR) between automated insulin delivery (AID) systems in youth with low bolus frequency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                    <jats:p>Youth using Omnipod 5 (OP5) or Tandem Control-IQ (CIQ) averaging \u22643.0 boluses\/day over 90 days were included. Propensity score matching accounted for between-group differences. A multiple linear regression model assessed for differences in TIR by system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A total of 202 youth had low bolus frequency (n = 75 of 290 using CIQ, n = 127 of 535 using OP5; P = 0.5). Propensity score matching paired 98 youth for analyses and eliminated between-group differences, excluding time in AID, which remained higher for CIQ users (80.0% vs. 64.0%; P = 0.01). There was no between-group difference in user-initiated boluses (2.2 boluses\/day). Adjusted TIR was 8.0% higher in CIQ users (54.9% vs. 46.9%; P = 0.002).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Among AID users receiving \u22643.0 boluses\/day, CIQ use was associated with greater TIR, likely due to increased time in AID and AID-initiated boluses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2337\/dc25-2082","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T16:43:26Z","timestamp":1765471406000},"page":"303-307","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Low Bolus Frequency on Automated Insulin Delivery System Performance in Youth With Type 1 Diabetes"],"prefix":"10.2337","volume":"49","author":[{"given":"Prerana","family":"Chatty","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Diabetes, Children\u2019s Hospital of Philadelphia 1 , Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Gera","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes, Children\u2019s Hospital of Philadelphia 1 , Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Rearson","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes, Children\u2019s Hospital of Philadelphia 1 , Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica N.","family":"Mountain","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes, Children\u2019s Hospital of Philadelphia 1 , Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Alicea-Trelles","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes, Children\u2019s Hospital of Philadelphia 1 , Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Gallop","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, University of Pennsylvania 2 , Philadelphia, PA"},{"name":"Department of Mathematics, West Chester University, West Chester 3 , PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4849-9774","authenticated-orcid":false,"given":"Brynn E.","family":"Marks","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes, Children\u2019s Hospital of Philadelphia 1 , Philadelphia, PA"},{"name":"Perelman School of Medicine, University of Pennsylvania 4 , Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"2026061811375305800_B1","doi-asserted-by":"crossref","first-page":"S146","DOI":"10.2337\/dc25-S007","article-title":"7. 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