{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T23:39:28Z","timestamp":1792885168679,"version":"4.5.0"},"reference-count":16,"publisher":"American Diabetes Association","issue":"4","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.diabetesjournals.org\/journals\/pages\/license"}],"funder":[{"DOI":"10.13039\/100013322","name":"EFPIA","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100013322","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Obesity Action Coalition"},{"name":"Breakthrough T1D"},{"name":"T1D Exchange"},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Innovative Medicines Initiative 2 Joint Undertaking","award":["875534"],"award-info":[{"award-number":["875534"]}]}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To assess the effect of metabolic bariatric surgery (MBS) in people living with type 1 diabetes (T1D) and obesity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                    <jats:p>From retrospective multicenter data, total weight loss, daily insulin requirement, HbA1c, and cardiometabolic parameters were assessed before and after surgery. Longitudinal models were used to identify response determinants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>This study included 162 people living with T1D and obesity. One year after surgery, mean total weight loss percentage was 29.7% (interquartile range [IQR] = 29.4, 30.3). Insulin requirements dropped from 0.75 (IQR = 0.58, 1.00) units\/kg\/day to 0.32 (IQR = 0.23, 0.43) units\/kg\/day (P &amp;lt; 0.001), and HbA1c dropped from 64.0 (IQR = 57.0, 74.0) mmol\/mol to 60.0 (IQR = 53.4, 68.0) mmol\/mol (P &amp;lt; 0.001). LDL, HDL, total cholesterol, and triglyceride levels significantly improved after surgery (P &amp;lt; 0.001). Greater total weight loss was associated with reduced insulin requirements, and higher baseline HbA1c was associated with poorer postsurgery glycemic control.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>MBS was associated with substantial metabolic improvement in people with T1D and obesity, in particular in those with high HbA1c and insulin need at baseline.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2337\/dc25-2295","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T15:57:43Z","timestamp":1771430263000},"page":"658-663","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":3,"title":["Impact of Metabolic Bariatric Surgery on Weight Loss and Glycemic Control in Adults With Type 1 Diabetes: A Multicenter Retrospective Cohort Study"],"prefix":"10.2337","volume":"49","author":[{"given":"Rieneke","family":"van der Meer","sequence":"first","affiliation":[{"name":"Nederlandse Obesitas Kliniek, Huis ter Heide 1 , the Netherlands"},{"name":"Department of Endocrinology & Metabolism, Amsterdam Institute for Gastroenterology, Endocrinology and Metabolism, Amsterdam University Medical Center 2 , Amsterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Pazmino","sequence":"additional","affiliation":[{"name":"Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism 3 , KU Leuven, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nele","family":"Steenackers","sequence":"additional","affiliation":[{"name":"Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism 3 , KU Leuven, Leuven, Belgium"},{"name":"Department of Nutrition and Movement Sciences, School for Nutrition and 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