{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:51:12Z","timestamp":1791496272818,"version":"4.3.4"},"reference-count":0,"publisher":"American Diabetes Association","license":[{"start":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:00:00Z","timestamp":1791417600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.diabetesjournals.org\/journals\/pages\/license"}],"funder":[{"name":"AVAD"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To evaluate whether a continuous glucose monitoring (CGM) system (CGMS)\u2013guided insulin optimization can improve glucose control and nutritional status in insulin-treated patients receiving long-term nocturnal parenteral nutrition (PN).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                    <jats:p>In this prospective single-center study, 12 insulin-treated adults with chronic intestinal failure undergoing nocturnal cyclic PN underwent 30-day CGM assessment before and after a diabetologist-led optimization of insulin therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Glucose profiles improved after the intervention: less time &amp;gt;250 mg\/dL (27% to 17%; \u2212139 \u00b1 113 min\/day; P = 0.02), more time in range (44% to 59%; +206 \u00b1 118 min\/day; P = 0.002), and without more hypoglycemia. HbA1c decreased by \u22120.7% (\u22128 mmol\/mol; P = 0.04), and glycosuria resolved in all affected patients (P = 0.03). Body weight increased by +5 kg (interquartile range 4\u20137.75; P = 0.006), as did serum albumin (+8 g\/L; P = 0.006). Malnutrition resolved among 8 of 11 participants (P &amp;lt; 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>CGMS-guided insulin optimization was associated with improvements in glucose control and nutritional status.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2337\/dc26-0936","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:25:55Z","timestamp":1791494755000},"update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":0,"title":["Continuous Glucose Monitoring\u2013Guided Insulin Optimization in Patients Receiving Nocturnal Parenteral Nutrition"],"prefix":"10.2337","author":[{"given":"Laurianne","family":"Kerlogot","sequence":"first","affiliation":[{"name":"1Service de Gastroent\u00e9rologie et nutrition clinique, H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Rigalleau","sequence":"additional","affiliation":[{"name":"2Service de Diab\u00e9tologie, H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gauthier","family":"Pellet","sequence":"additional","affiliation":[{"name":"1Service de Gastroent\u00e9rologie et nutrition clinique, H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance","family":"Chevrier","sequence":"additional","affiliation":[{"name":"1Service de Gastroent\u00e9rologie et nutrition clinique, H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coraline","family":"Bald\u00e9","sequence":"additional","affiliation":[{"name":"1Service de Gastroent\u00e9rologie et nutrition clinique, H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Wilsius","sequence":"additional","affiliation":[{"name":"1Service de Gastroent\u00e9rologie et nutrition clinique, H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Pidoux","sequence":"additional","affiliation":[{"name":"1Service de Gastroent\u00e9rologie et nutrition clinique, H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Jeamart","sequence":"additional","affiliation":[{"name":"1Service de Gastroent\u00e9rologie et nutrition clinique, H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0478-4258","authenticated-orcid":false,"given":"Florian","family":"Poullenot","sequence":"additional","affiliation":[{"name":"1Service de Gastroent\u00e9rologie et nutrition clinique, H\u00f4pital Haut-L\u00e9v\u00eaque, CHU de Bordeaux, Pessac, France"},{"name":"3Immunology from Concept and Experiments to Translation (ImmunoConcEpT), CNRS, UMR 5164, University of Bordeaux, Bordeaux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2026,10,8]]},"container-title":["Diabetes Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/doi\/10.2337\/dc26-0936\/898046\/dc260936.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/doi\/10.2337\/dc26-0936\/898046\/dc260936.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:25:56Z","timestamp":1791494756000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/care\/article\/doi\/10.2337\/dc26-0936\/172753\/Continuous-Glucose-Monitoring-Guided-Insulin"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,8]]},"references-count":0,"URL":"https:\/\/doi.org\/10.2337\/dc26-0936","relation":{},"ISSN":["0149-5992","1935-5548"],"issn-type":[{"value":"0149-5992","type":"print"},{"value":"1935-5548","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,8]]},"article-number":"dc260936"}}